Clinical trials: Citrate
Enhanced Recovery After Surgery in a Pediatric Population
Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population
Dexmedetomidine (Dex), a selective α2-adrenergic receptor agonist, is the most used sedative for procedural sedation in children and in pediatric Intensive Care Unit (PICU) because it is associated with less respiratory…
- Trial name
- NCT06538584
- Testing
- Caffeine citrate 15mg/kg, 0.9% Sodium Citrate
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Osteoporosis, Osteopenia
Melatonin-Micronutrients for Osteopenia Treatment Study
The investigators' long-term goal is to employ novel methods to improve bone formation and bone density in women (and men) with osteopenia or osteoporosis while also decreasing signs and symptoms of degenerative joint and disc…
- Trial name
- MOTS (NCT01870115)
- Testing
- Fiber Pill, Melatonin, Strontium citrate, Vitamins D3 and K2
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Endometrial Carcinoma, Recurrent Uterine Corpus Carcinoma
Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer
This randomized phase II trial studies how well temsirolimus with or without megestrol acetate and tamoxifen citrate works in treating patients with endometrial cancer that has spread to other places in the body and usually…
- Conditions
- Endometrial Carcinoma, Recurrent Uterine Corpus Carcinoma, Stage IIIA Uterine Corpus Cancer, Stage IIIB Uterine Corpus Cancer
- Trial name
- NCT00729586
- Testing
- Laboratory Biomarker Analysis, Megestrol Acetate, Tamoxifen Citrate
- Where
- 108 sites in United States
- Volunteers
- 73 people
- Sponsor
- National Cancer Institute (NCI)
Cancer, Breakthrough Pain
Efficacy/Safety Study of ACTIQ® for Opioid-Tolerant Children and Adolescents With Breakthrough Pain (BTP)
The primary objective of the study is to evaluate the efficacy of ACTIQ treatment for the management of breakthrough pain (BTP) compared to placebo treatment in children with cancer and non-cancer pain who are receiving…
- Trial name
- NCT00236041
- Testing
- ACTIQ®
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 38 people
- Sponsor
- Cephalon
Hyperphosphatemia Related to Chronic Kidney Disease
Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease
This study will be conducted to assess the safety and tolerability of ferric citrate in pediatric participants with hyperphosphatemia related to chronic kidney disease (CKD).
- Trial name
- NCT04523727
- Testing
- ferric citrate
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Keryx Biopharmaceuticals
Hyperuricosuria, Hypocitraturia
Comparison of Different Methods for Measuring Urinary Oxalate and Citrate: An Observational Study
This observational study aims to compare three different laboratory methods for measuring urine oxalate and citrate concentrations.
- Trial name
- Comparison of (NCT06916559)
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease
Study to Evaluate the Safety and Tolerability of KRX-0502 (Ferric Citrate) in Children With Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease
This study will be conducted to evaluate the safety and tolerability of ferric citrate in pediatric participants with iron deficiency anemia (IDA) associated with non-dialysis dependent chronic kidney disease (NDD-CKD).
- Trial name
- NCT04649411
- Testing
- ferric citrate, standard of care
- Sponsor
- Keryx Biopharmaceuticals
Secondary Hypothyroidism
Thyroid Function in Critically Ill Patients With Acute Kidney Injury
The objective of this study was to assess the changes in thyroid hormones and its activity during CRRT in patients with Acute Kidney Injury.
- Trial name
- NCT04767763
- Testing
- Assessment of TSH, fT3, fT4,TRH, TT3, TT4, rT3 in patients with CVVHDF
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Gdansk
Glucose Transporter Type 1 Deficiency Syndrome, GLUT1 Deficiency Syndrome
Treatment Development for Glucose Transporter Type I Deficiency Syndrome (G1D)
The purpose of this trial is to determine if an alternative energy source will impact brain metabolism in a disorder characterized by glucose metabolism failure in the brain.
- Trial name
- NCT02018315
- Testing
- Triheptanoin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Juan Pascual
Complication of Dialysis
Observational Study of Citrate Based Dialysis in Pediatric Patients Receiving Hemodialysis
Providing hemodialysis requires the use of an extracorporeal circuit which must be anticoagulated. Inadequate anticoagulation can result in the dialyzer clotting with decreased circuit blood flows, inefficient dialysis and even…
- Trial name
- NCT01590550
- Testing
- Use of citrate based dialysate
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Loma Linda University
Infertility, Female
Different Induction Protocols in PCOS After Clomiphene Citrate Failed Pregnancy in Non-IVF Cycles
The aim of this study will be to compare between 4 different induction protocols in women who: 1. Failed to achieve ovulation after clomiphene citrate treatment at a dose of 150mg daily (if the patient can tolerate this dose) for…
- Trial name
- NCT05362799
- Testing
- Letrozol (Femara, Novartis), Letrozol (Femara, Novartis) combined with Metformin (Cidophage 500 mg, Cid Pharmaceuticals, Egypt), highly purified lyophilized Uroffollitropin (Fostimon, IBSA Institut Biochimique SA, Lugano, Switzerland)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Acute Kidney Injury, Renal Failure
Analysis of Continuous Kidney Replacement Therapy (CKRT) Treatments With multiFlux Hemofilters Using Regional Citrate Anticoagulation (RCA) or Systemic Heparin Anticoagulation
The goal of this observational study is to assess the performance of the multiFlux hemofilterwith regional or systemic anticoagulation during CKRT treatments.
- Trial name
- RCA-Flux (NCT07679568)
- Testing
- multiFlux 160 hemofilter with regional heparin anticoagulation, multiFlux 160 hemofilter with RCA with regional citrate anticoagulation, multiFlux 130 hemofilter with regional heparin anticoagulation
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Separation Anxiety
Effects on Recovery of Children of Intravenous Formulation of Fentanyl Citrate and Midazolam Orally for Premedication
To study and compare the efficacy of intravenous formula of fentanyl citrate and midazolam administered orally for premedication in paediatric surgical patients.
- Trial name
- NCT05500599
- Testing
- Fentanyl Citrate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Sodium Picosulfate Overdose, Magnesium Sulfate Overdose
Picoprep Split-dose Before Colonoscopy in Children
Before having a colonoscopy, it is necessary to clean the intestine well in order to have a complete view of the intestinal mucosa.
- Conditions
- Sodium Picosulfate Overdose, Magnesium Sulfate Overdose, Children, Only, Bowel Disease
- Trial name
- NCT04767633
- Testing
- split dose vs standard dose of sodium pico sulfate plus magnesium sulfate in children for bowel cleansing
- Volunteers
- 590 people
- Sponsor
- Azienda Ospedaliera "Sant'Andrea"
Cognitive Function, Anxiety
A Virtual Clinical Trial to Examine the Effect of Magnesium Choline Citrate on Cognitive Function and Anxiety in Healthy Adolescents and Adults
The goal of this clinical trial is to examine the effect of Magnesium Choline Citrate on cognitive function and anxiety in healthy adolescents and adults.
- Trial name
- NCT07685613
- Testing
- Magnesium Choline Citrate
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nutrisol, LLC
Preterm Birth
Effect of Early Use of Caffeine Citrate in Preterm Neonates
This work is designed to study the effect of the early use of caffeine citrate in preterm neonates who need respiratory support on morbidity and short term neonatal outcome.
- Trial name
- NCT04001712
- Testing
- Caffeine Citrate
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Ain Shams University
Breast Cancer
Study of Estrogen Levels in Premenopausal Women Who Have Undergone Surgery for Breast Cancer and Are Receiving Triptorelin and Tamoxifen Citrate or Exemestane on Clinical Trial IBCSG 24-02
RATIONALE: Studying samples of blood from patients with breast cancer in the laboratory may help doctors learn how well triptorelin given together with tamoxifen citrate or exemestane works in lowering estrogen levels.
- Trial name
- SOFT-EST (NCT00975676)
- Testing
- gas chromatography / tandem mass spectometry
- Where
- 24 sites in France, Hungary and 6 more
- Volunteers
- 123 people
- Sponsor
- ETOP IBCSG Partners Foundation
Apnea of Prematurity, Premature Birth
The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate
The goal of this clinical trial is to answer whether the use of a single loading dose (20 mg/kg) of caffeine citrate one hour before extubation has an impact on the success rate of extubation among preterm neonates.
- Conditions
- Apnea of Prematurity, Premature Birth, Respiratory Failure
- Trial name
- NEOKOFF22 (NCT06401083)
- Testing
- Caffeine citrate
- Where
- 2 sites in Hungary
- Volunteers
- 226 people
- Sponsor
- Semmelweis University
Pulmonary Arterial Hypertension, Pulmonary Hypertension
Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety
As sitaxsentan is the agent most highly selective for ETA (Endothelin Type A (receptor)), and does not significantly impact sildenafil pharmacokinetics the combination of most promise for pulmonary arterial hypertension (PAH)…
- Trial name
- NCT00796510
- Testing
- Sitaxsentan, Sitaxsentan and Sildenafil
- Where
- 3 sites in United States, Romania and 1 more
- Volunteers
- 3 people
- Sponsor
- Pfizer
Cardiopulmonary Bypass
Does Sildenafil Protect Against Pulmonary Related Complications Following Cardiopulmonary Bypass?
Does pre-operative administration of Sildenafil (Viagra, Pfizer) reduce the lung injury associated with cardiopulmonary bypass in children undergoing corrective surgical repair of congenital heart disease.
- Trial name
- NCT00350441
- Testing
- Sildenafil Citrate
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- NHS Greater Glasgow Yorkhill Division