Clinical trials: Clear Aligner Therapy
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Patient Comfort, Malocclusion
Comparison of Patient-Reported Comfort Between Two Clear Aligner Trimming-Line Designs: A Split-Mouth Study
The trimming-line design of clear aligners (supragingival versus juxtagingival) is a routine clinical decision whose influence on patient-reported comfort has not been established; available evidence on aligner comfort derives…
- Conditions
- Patient Comfort, Malocclusion, Oral Health
- Trial name
- COMFORT-ALIGN (NCT07660809)
- Testing
- Supragingival trimming-line design, Juxtagingival festooned trimming-line design
- Where
- Romania
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Root Resorption, Pain
Side Effects of Different Treatment Methods
this study aimed to compare the effects of fixed orthodontic treatment and clear aligner therapy on root resorption, periodontal status, pain experience and chewing performance.
- Conditions
- Root Resorption, Pain, Chewing Function
- Trial name
- NCT06709287
- Testing
- clear aligners, orthodontic metal bracket
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Endocrine Disruptors
A Comparison of Direct 3D Printed Clear Aligner System and Indirect Clear Aligner Systems With Fixed Orthodontic Treatment in Terms of Endocrine Disrupting Monomer Release, Treatment Effectiveness and Efficiency
The aim of this study is to evaluate the release of endocrine disrupting monomers from clear aligners as a result of exposure to intraoral factors by measuring their concentration in saliva and to evaluate their reliability of…
- Trial name
- NCT06685029
- Testing
- Clear aligner treatment, Fixed Orthodontic Appliance Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ahmet Yağcı
Clear Aligner Therapy, Aligner Attachment Wear
Clinical Evaluation of Customized Attachment Composites in Clear Aligner Therapy
This prospective observational clinical study aims to evaluate the three-dimensional surface wear and clinical survival of orthodontic attachments fabricated with customized composite materials used in clear aligner therapy.
- Trial name
- NCT07261735
- Testing
- GC G-ænial A'Chord Universal Composite, Spectra ST HV (High Viscosity), Spectra ST LV (Low Viscosity)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Composite Resins, Clear Aligner Therapy
Surface Wear of Clear Aligner Attachment Composites
The aim of this study is to investigate the amount of surface wear that may occur during treatment with different composite materials used for clear aligner attachments.
- Trial name
- NCT07812220
- Testing
- GC Aligner Connect, VOCO AlignerFlow LC
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Marmara University
Skeletal Class III Malocclusion
Skeletal and Dentoalveolar Effects of Functional Clear Aligner Therapy in Growing Patient With Skeletal Class III Malocclusion
The purpose of this study is to evaluate the skeletal, dentoalveolar \& soft tissue effects of functional clear aligner therapy in growing patient with Skeletal class III malocclusion.
- Trial name
- NCT07703007
- Testing
- Functional Clear Aligner
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Mansoura University
Juvenile Idiopathic Arthritis, Malocclusion, Angle Class II
Mandibular Advancement Clear Aligner Treatment in Juvenile Idiopathic Arthritis Subjects
There is currently no information on how mandibular advancement therapy could influence three-dimensionally the condylar and mandibular morphology in growing patients affected by Juvenile Idiopathic Arthritis (JIA).
- Trial name
- NCT05467579
- Testing
- Device: orthodontic - mandibular advancement clear aligner
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Genova
Malocclusion, Esthetics, Dental
Effect of Finishing Clear Aligner Marginal Termination Design (Supragingival vs Juxtagingival) on Aligner Color Stability After 14 Days of Wear: A Split-Mouth Study
The goal of this clinical study is to learn whether the gumline edge design of a finishing orthodontic clear aligner affects how much the aligner's color changes after 14 days of wear.
- Trial name
- SPECTRO-ALIGN (NCT07628491)
- Testing
- Tri-layer thermoplastic finishing clear aligner
- Where
- Romania
- Volunteers
- 50 people
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Composite Resins, Clear Aligner Therapy
Color Stability and Fluorescence Properties of Two Aligner Attachment Composites
This split mouth study aims to evaluate whether 2 different composite materials used for making clear aligner attachments change color over time and do they have different fluorescent characteristics when illuminated with…
- Trial name
- NCT07806214
- Testing
- GC Aligner Connect, VOCO AlignerFlow LC
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Marmara University
Distalization, Class II Malocclusion
Comparison of Distalization of Maxillary First and Second Molars Between a Miniscrew Implant Supported Device and Clear Aligners.
The goal of this randomized clinical trial is to compare distalization of maxillary first and second molars achieved with a device supported with mini screw implants in the palate (Advanced Molar Distalization Appliance, AMDA®)…
- Conditions
- Distalization, Class II Malocclusion, Aligner Therapy, Distalization by Miniscrews
- Trial name
- NCT07040176
- Testing
- Upper molar distalization
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki