Clinical trials: Cleft Palate Repair
Cleft Palate
Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials
Investigator initiated retrospective chart review to study the effects of changing suture material on the healing and outcome of cleft palate surgery were.
- Trial name
- NCT00584272
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Davis
Nasoalveolar Fistula (Defect)
Clinical Assessment of Usage of Cleft Margin Flap With Anterior Palatal Closure in Closure of Naso-alveolar Defect.
During primary cleft lip repair in patients who were born with cleft lip and palate, usage of cleft margin flap with anterior palatal closure will be done in an attempt to close the Naso-alveolar fistula (defect) that usually…
- Trial name
- NCT03922438
- Testing
- usage of cleft margin flap with anterior palatal closure during primary cleft lip repair.
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Palate
Furlow With Buccinator and Fistula Formation
Furlow with buccal myomucosal flap (group 1) Local anesthesia with a vasoconstrictor will be injected at the beginning of the surgery after Z- flap outline marking.
- Trial name
- NCT07840911
- Testing
- furlow with buccinator, two flap palatoplasty
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Cleft Palate
Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair
The primary objective of this study is to evaluate the efficacy of administering intravenous dexmedetomidine as a single preemptive dose to placebo in reducing the total 24 hour dose of opioids as measured on a weight adjusted…
- Trial name
- NCT02915042
- Testing
- Dexmedetomidine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Cleft Lip Palate
Quadratus Lumborum Block for Iliac Bone Harvest in Pediatric Cleft Alveolus Repair
This prospective, randomized, double-blinded controlled trial will investigate the effectiveness of a lateral quadratus lumborum (QL) block in 50 children aged 6-14 years undergoing iliac crest bone grafting for cleft alveolus…
- Trial name
- NCT07846761
- Testing
- Lateral quadratus lumborum block
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Cleft Palate
Optic Nerve Sheath Diameter Measurement in Cleft Palate Repair
The aim of this study is to evaluate the effect of the Boyle-Davis mouth opener, which is routinely used in cleft palate surgery, on intracranial pressure by USG-guided optic nerve sheath diameter measurement, which is a…
- Trial name
- NCT04718558
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karadeniz Technical University
Cleft Palate
Sleep and Behavior in Children With Cleft Palate
The purpose of this study is to determine whether cleft palate repair increases the risk for obstructive sleep apnea in children and whether sleep apnea could explain learning and behavior difficulties that are often observed.
- Trial name
- NCT01046591
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cleft Palate, Jaw Abnormalities
Improving Informed Consent for Cleft Palate Repair
To determine if providing a written document in addition to the standard oral discussion of surgical risks improves risk recall for the parents/guardians of a child seen in consultation for cleft palate surgery, and if this has…
- Conditions
- Cleft Palate, Jaw Abnormalities, Maxillofacial Abnormalities, Mouth Abnormalities
- Trial name
- NCT02595307
- Testing
- Pamphlet
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- IWK Health Centre
Cleft Palate
The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency Repair
Cleft Lip and Palate surgical repair is one of the most common procedures performed by Plastic and Reconstructive Surgeons in the World.
- Trial name
- Cleft Palate (NCT02688634)
- Testing
- Amoxicillin
- Where
- 2 sites in United States
- Sponsor
- University of Florida
Cleft Palate
A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation
The hypothesis of this study is to investigate and compare the efficacy between the administrations of single intravenous (IV) dose of dexmedetomidine versus normal saline in preventing immediate postoperative agitation in…
- Trial name
- NCT04928391
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cleft Palate, Cleft Palate, Unilateral, Complete
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair.
- Conditions
- Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair
- Trial name
- NCT07514091
- Testing
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Palate, Fistula of Soft Palate (Disorder)
LIMA Protocol Towards Palatal Fistula and Maxillary Growth in Cleft Palate
This randomized controlled trial compared palatoplasty outcomes using the LIMA protocol (Hybrid and one-flap techniques) versus the RSCM protocol (two-flap technique) in patients with unilateral Veau III-IV cleft palate at Cipto…
- Conditions
- Cleft Palate, Fistula of Soft Palate (Disorder), Maxillar Hypoplasia
- Trial name
- NCT07137169
- Testing
- LIMA protocol, RSCM Protocol
- Where
- Indonesia
- Volunteers
- 35 people
- Sponsor
- Universitas Indonesia
Cleft Palate
Effect of Furlow Palatoplasty With Buccal Myomucosal Flap on the Speech Development
About 20 patient will be collected according to the eligibility criteria and grouped into Group I : 10 patients were treated with furlow with buccinators flap Group II : 10 patients were treated with 2 flap palatoplasty All…
- Trial name
- NCT06856330
- Testing
- furlow with buccal myomucosal flap, two flap palatoplasty
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Fayoum University
Cleft Palate
IV Acetaminophen in Children Undergoing Palatoplasty
This project is being used to assess the utility of intravenous acetaminophen in the pediatric population undergoing palate repairs. This study is a prospective randomized double blinded placebo controlled study.
- Trial name
- NCT01760330
- Testing
- IV acetaminophen
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
Velopharyngeal Insufficiency
Buccinator Myomucosal Flap With Furlow Palatoplasty and VPI
Nasopharyngoscopic examination of the 20 patients with secondary VPI following 2 flap palatoplasty will be done for visualization of the velopharyngeal port, allowing assessment of the pattern and grade of velopharyngeal closure…
- Trial name
- NCT05626933
- Testing
- Buccinator myomucosal flap with Furlow palatoplasty
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Complication Following Peripheral Nerve Block
Nalbuphine as Adjuvant During Bilateral Suprazygomatic Maxillary Nerve Block for Pediatric Cleft Palate Repair
The aim of this study is to evaluate the efficacy of adding nalbuphine to bupivacaine via suprazygomatic nerve block for postoperative pain control and emergence agitation management in pediatrics aged from to 1 to 7 years who…
- Trial name
- NCT06100315
- Testing
- Nalbuphine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cleft Lip and Palate
Unilateral Cleft Repair in One Surgery With Pure Primary Healing
Retrospective analysis of the current surgical method to repair unilateral cleft lip and palate malformations at our centre
- Trial name
- NCT04108416
- Testing
- Cleft lip and palate repair
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University Hospital, Basel, Switzerland
Cleft Palates
Preventing Complications in Cleft Palate Repair With Antibiotics
The primary objective of this study is to determine the efficacy of administering a single dose of preoperative antibiotics to prevent complications in patients undergoing primary closure of a cleft secondary palate.
- Trial name
- NCT00760006
- Testing
- Unasyn, saline solution
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Joseph Losee
Mouth Abnormalities, Cleft Palate
Evaluation of Trigeminal Nerve Blockade
Cleft palate repair requires high doses of opioids for pain control postop. An alternative approach is placement of nerve blocks in the pterygopalatine fossa bilaterally, blocking the maxillary nerve \& covering the entire…
- Conditions
- Mouth Abnormalities, Cleft Palate, Birth Defect
- Trial name
- NCT03632044
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Cleft Lip, Cleft Palate +/- Lip
Comparative Study of Regional Nerve Blocks in Primary Cleft Palate Repair
This study will evaluate whether adding a suprazygomatic maxillary nerve block to the standard palatal nerve block improves pain control after cleft palate repair surgery in children.
- Conditions
- Cleft Lip, Cleft Palate +/- Lip, Pain Management, Wound Dehiscence, Surgical
- Trial name
- NCT07892963
- Testing
- Palatal Nerve Block, Suprazygomatic Maxillary Nerve Block
- Volunteers
- 144 people
- Sponsor
- Children's National Research Institute