Clinical trials: Cleft Palate Repair
Cleft Palate
Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient
36 cleft palate patients had residual oronasal fistula included in this study divided randomly to two groups group I (control group): the fistula was repaired using two layers (oral and nasal layers) group II (study group): The…
- Trial name
- NCT06807450
- Testing
- closure of oro-nasal fistula in cleft palate patients
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cleft Palate
Optic Nerve Sheath Diameter in Patients Undergoing Palatoplasty
The purpose of this study is to evaluate the change of the optic nerve sheath diameter according to the change of the neck position in pediatric patients undergoing palatoplasty.
- Trial name
- NCT03585608
- Testing
- Neck extension
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Cleft Palate, Plasma Rich in Growth Factors
Role of Plasma Rich Growth Factor in Repair Primary Cleft Palate
Does the plasma-rich growth factor (PRGF) with primary cleft palate repair accelerate wound healing and prevent post-operative oronasal fistula occurrence?
- Trial name
- PRGF (NCT06889181)
- Testing
- Plasma Rich in Growth Factors (PRGF)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Palate
Furlow With Buccinator and Fistula Formation
Furlow with buccal myomucosal flap (group 1) Local anesthesia with a vasoconstrictor will be injected at the beginning of the surgery after Z- flap outline marking.
- Trial name
- NCT07840911
- Testing
- furlow with buccinator, two flap palatoplasty
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Cleft Palate
An Investigation for the Optimal Timing of a Cleft Palate Repair
The effect of timing of cleft palate repair on speech development, velopharyngeal functioning, and facial growth remains unknown.
- Trial name
- NCT00779961
- Testing
- Palatoplasty
- Where
- Canada
- Volunteers
- 320 people
- Sponsor
- The Hospital for Sick Children
Cleft Palate
Fistiulation Rate Following Primary Cleft Repair≤
Aim : The aim of present study was to evaluate the buccinator flap utilization in primary cleft palatoplasty on fistulation rate.
- Trial name
- NCT05166408
- Testing
- Buccinator myomucosal flap, Bardach two flap palatoplasty
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fistula of Soft Palate (Disorder)
Evaluation of the Incidence of Palatal Fistula in Furlow Double-opposing Z-plasty vs. Two-flap Palatoplasty for Cleft Palate Repair
Evaluation of the incidence of palatal fistula in Furlow double-opposing z-plasty versus two-flap palatoplasty for cleft palate repair.
- Trial name
- NCT03055637
- Testing
- Furlow double opposing z-plasty, Two flap palatoplasty
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sarah Moustafa Mahmoud Fahmy El-Youtti
Cleft Palate, Cleft Palate, Unilateral, Complete
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair.
- Conditions
- Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair
- Trial name
- NCT07514091
- Testing
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Lip and Palate, Cleft Palate
Three-dimensional Cleft Lip and Palate Morphology Prior to One-stage Cleft Repair
This is a prospective observational cohort study of consecutive patients with cleft lip and palate deformity undergoing cleft repair at the Institute of Mother and Child in Warsaw.
- Conditions
- Cleft Lip and Palate, Cleft Palate, Craniofacial Deformity
- Trial name
- NCT04616690
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Cleft Lip, Cleft Palate
Cleft Palate Surgery and Speech Development
Compare the outcome of two primary surgeries techniques (von Langenbeck and Furlow double z-plasty) performed on children with cleft lip/palate to determine if one results in significantly better velopharyngeal competency for…
- Trial name
- NCT00004639
- Testing
- Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
- Where
- 2 sites in United States, Brazil
- Volunteers
- 475 people
- Sponsor
- University of Florida
Cleft Palate
Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials
Investigator initiated retrospective chart review to study the effects of changing suture material on the healing and outcome of cleft palate surgery were.
- Trial name
- NCT00584272
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Davis
Cleft Lip and Palate
Tissue Engineered Constructs for Alveolar Cleft Repair
Description of the research question In children undergoing unilateral alveolar cleft reconstruction, would stem cells carried on collagen scaffold provide bone of a good quality and quantity if compared to autogenous bone…
- Trial name
- NCT03563495
- Testing
- tissue engineered group, autogenous bone graft group
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Palate, Pain
Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
- Conditions
- Cleft Palate, Pain, Postoperative Care, Perioperative Care
- Trial name
- OPAL-Cleft (NCT06962306)
- Testing
- Methadone hydrochloride, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Cleft Lip Palate
Safety and Efficacy of Bone Bioengineering Kit With Stem Cells for Alveolar Cleft Repair
The objective of this study is to compare the safety and efficacy of a bone tissue engineering kit - composed of 10⁶ autologous mesenchymal stem cells derived from deciduous dental pulp combined with Bio-Oss® Collagen - with…
- Trial name
- NCT07305623
- Testing
- Bioengineering kit composed of stem cells from deciduous teeth and biomaterial., iliac crest bone graft surgery
- Where
- 2 sites in Brazil
- Volunteers
- 205 people
- Sponsor
- Instituto de Tecnologia do Paraná
Pierre Robin Syndrome, Cleft Palate
Postoperative Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative Considerations
In cleft surgery there is no current general agreement on the treatment strategy of patients with the Pierre Robin Sequence. The timing of surgery and the surgical approach depends on the treating physician or the hospital…
- Trial name
- NCT02658318
- Where
- Belgium
- Volunteers
- 92 people
- Sponsor
- AZ Sint-Jan AV
Cleft Palate, Unilateral, Complete
Palatal Lengthening Using Buccinator Myomucosal Flaps with Furlow Z-plasty Technique for Primary Cleft Palate Repair
: Cleft palate is a congenital deformity caused by abnormal facial development during intra-uterine life. Worldwide, the prevalence of cleft lip/palate is about 1:1000 live births.
- Trial name
- NCT04346173
- Testing
- furlow z plasty with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Mahmoud Akram
Cleft Palate
Effect of Neck Extension on Intraocular Pressure in Patients Undergoing Palatoplasty
The purpose of this study is to investigate the change in intraocular pressure according to the neck extension during palatoplasty in pediatric patients.
- Trial name
- NCT04683978
- Testing
- Position
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Asan Medical Center
Cleft Palate
Mordified Restoration of Tensor Veli Palatini in Cleft Palate Repair
to study the benefical audiological and/or otological effect by mordified restoration of tensor veli palatini in cleft palate repair compared to traditional Langenbeck's repair and merely levator veli palatini restoration.
- Trial name
- NCT04366674
- Testing
- cleft palate repair
- Volunteers
- 71 people
- Sponsor
- Peking Union Medical College Hospital
Cleft Palate Children, Laser
Low Level Laser in Isolated Cleft Palate Repair Versus Surgical Correction Without LLL in Healing Process
Does the use of low level laser (LLL) after surgical correction of cleft palate improve healing and decrease incidence of oronasal fistula?
- Trial name
- NCT03688737
- Testing
- low level laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Palate
A Single Bolus of Dexmedetomidine Versus Normal Saline in Postoperative Agitation
The hypothesis of this study is to investigate and compare the efficacy between the administrations of single intravenous (IV) dose of dexmedetomidine versus normal saline in preventing immediate postoperative agitation in…
- Trial name
- NCT04928391
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University