Clinical trials: Clinical Practice Guideline
Overweight, Obesity
Meta-analyses of the Effect of Liquid Meal Replacements on Cardiometabolic Risk
Obesity is a major risk factor for cardiovascular disease and diabetes. Weight loss is an important therapeutic goal for overweight and obese patients to reduce their risk of developing cardiovascular disease and diabetes.
- Conditions
- Overweight, Obesity, Type 2 Diabetes
- Trial name
- NCT02779790
- Testing
- Liquid Meal Replacements
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Airway Assessment
Airway Survey - International Airway Assessment Practices (2023-2028)
This international, multicenter, observational survey study aims to assess current clinical practices in preoperative airway assessment in Germany, Austria, and Switzerland at both the institutional and individual…
- Trial name
- AirwaySurvey (NCT07886060)
- Testing
- Structured Survey on Preoperative Airway Assessment
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Clinical Decision Support, Clinical Practice Guidelines
Professional Development in Emergency Medical Services
The ProDEms-trial focuses on nurses and ambulance drivers working in prehospital care, taking care on the one hand of patients suffering from time-sensitive critical conditions like STEMI, acute stroke or severe traumatic brain…
- Conditions
- Clinical Decision Support, Clinical Practice Guidelines, Emergency Medical Services
- Trial name
- ProDEms (NCT02365792)
- Testing
- Clinical Decision Support Tool for Prehospital Care
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- KU Leuven
Diabetes Mellitus, Chronic Disease
Meta-analyses of Liquid Versus Solid Calories and Body Weight
Consumption of sugar-sweetened beverages (SSBs) has been linked to rising rates of overweight and obesity. The most prominent mechanism to explain the link between SSBs and obesity is that liquid calories are not perceived by the…
- Conditions
- Diabetes Mellitus, Chronic Disease, Cardiovascular Diseases, Prediabetic State
- Trial name
- NCT02702440
- Testing
- Liquid calories from sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Dyslipidemia, Diabetes
Meta-analyses of Dietary Pulses and Cardiometabolic Risk
Dietary pulses, more commonly known as "legumes", are generally recognized as healthy components of the diet. Canada's Food Guide encourages consumptions of meat alternatives, such as beans "more often"; and the dietary…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01594567
- Testing
- Dietary pulses
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Premature Infants
The Effect of Using Clinical Guidelines on Kangaroo Care on Newborn and Maternal Outcomes
The aim of this study was to determine the effect of the use of clinical guidelines in kangaroo care (KB) practice on neonatal and maternal outcomes in premature infants.
- Trial name
- NCT05807191
- Testing
- Kangaroo care based on kangaroo care guide
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Ventilator Associated Pneumonia
Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia
The purpose of this prospective, multicentre, time-series study is to develop, implement, refine, and evaluate a sustainable behaviour change strategy in the intensive care unit (ICU).
- Trial name
- ABATEVAP (NCT00434460)
- Testing
- Education
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,320 people
- Sponsor
- Canadian Critical Care Trials Group
Neonatal Hyperbilirubinemia
Bilicurves: Using Information Technology to Improve the Management of Neonatal Hyperbilirubinemia
We will use information technology to integrate the 2004 American Academy of Pediatrics guidelines for management of neonatal hyperbilirubinemia with laboratory reporting of newborn bilirubin test results to improve physician…
- Trial name
- NCT00801619
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypertension
Guidelines for Drug Therapy of Hypertension: Multi-Site Implementation
Clinical trial of implementation of clinical practice guidelines for managing hypertension in primary care clinics.
- Trial name
- NCT00122161
- Testing
- ATHENA Decision Support System, An Automated Clinical Decision Support System for Health Care Providers, Profiling performance
- Where
- 3 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Smoking Cessation
ISTAPS: A Stepped Primary Care Smoking Cessation Intervention
Primary care centers can play a very important role in helping people to stop smoking. There is a large body of research on the effectiveness of specific interventions especially addressed to people who want to stop smoking.
- Trial name
- NCT00125905
- Testing
- Advice, Motivational Interviewing, Nicotine Gum and Patch
- Where
- Spain
- Volunteers
- 3,012 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Child Health, Clinical Practice Guidelines
An Evaluation of the Effectiveness of e-IMCI Implementation in Primary Health Care Clinics in South Africa.
The research hypothesis is that sick children attending primary health care (PHC) clinics who are managed by IMCI-trained health workers (HWs) using electronic Integrated Management of Childhood Illness guidelines (e-IMCI)…
- Conditions
- Child Health, Clinical Practice Guidelines, Primary Health Care
- Trial name
- NCT04074083
- Testing
- electronic IMCI, paper IMCI
- Where
- South Africa
- Volunteers
- 291 people
- Sponsor
- University of KwaZulu
Suicide Prevention, Social Media Users
Exploring The Effect of TikTok Trigger Warnings in a Clinical Sample of Youth at Risk of Suicide
Rates of suicide among Canadian youth have risen steadily over the past two decades, alongside rapid growth in social media use-especially TikTok.
- Trial name
- NCT07913854
- Testing
- Trigger Warning
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Disease, Diabetes
Meta-Analyses of Low-risk Lifestyle Behaviours and Patient Important Outcomes
Public health policy is universal in recommending the adoption of low risk low-risk lifestyle behaviors for health promotion and prevention of chronic or non-communicable diseases (NCDs).These behaviors generally include…
- Conditions
- Cardiovascular Disease, Diabetes, Cancer, Mortality
- Trial name
- NCT03234101
- Testing
- Low-risk lifestyle behaviours
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Infection Due to Indwelling Urinary Catheter, Asymptomatic Bacteriuria
Asymptomatic Bacteriuria Guideline Implementation Study
Overtreatment of asymptomatic bacteriuria (ABU) is a quality, safety, and cost issue, particularly as unnecessary antibiotics lead to emergence of resistant pathogens.
- Trial name
- ABU (NCT01052545)
- Testing
- Audit-Feedback
- Where
- United States
- Volunteers
- 1,598 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Coronary Heart Disease
Meta-analysis of Oat Fiber and Cardiovascular Risk Reduction
Oat fibre has been shown to lower cholesterol and may have cardioprotective effects. However, whether this translates to actual cardiovascular risk reduction is unclear, as there is a lack of controlled human trials.
- Trial name
- NCT05171283
- Testing
- Oats or Oat Fibre
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension, Cardiovascular Disease
Meta-analyses of the Effect of Legumes on Blood Pressure
Legumes are generally recognized as healthy dietary components, and although beans and legumes are recommended in food guidelines in North America, guidelines vary in regards to how much and how often these foods should be…
- Conditions
- Hypertension, Cardiovascular Disease, Dyslipidemia, Diabetes
- Trial name
- NCT02600338
- Testing
- Legumes
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Tobacco Use Cessation, Tobacco Smoking
EHR-Based and Fax-Based Referral to a Tobacco Quitline: A Comparative Study
This study is designed to assess whether completely electronic, HIPAA-compliant, EHR-based, closed-loop referrals for tobacco cessation from primary care clinics to a state telephone tobacco quitline service can increase the…
- Trial name
- NCT02735382
- Testing
- Tobacco quitline EHR referral, Tobacco quitline Fax referral
- Where
- United States
- Volunteers
- 14,930 people
- Sponsor
- University of Wisconsin, Madison
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto