Clinical trials: Clinical Practice Guidelines
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pediatric Obesity, Rural Health
iAmHealthy Clinical Practice Guideline (CPG)
The current study is a multilevel factorial design RCT with interventions at the clinic (Healthy Clinic intervention period vs. Control period) and individual patient levels (iAmHealthy vs. Newsletter).
- Conditions
- Pediatric Obesity, Rural Health, Clinical Practice Guideline
- Trial name
- NCT06888011
- Testing
- Participants: iAmHealthy, Participants: Newsletter
- Where
- 4 sites in United States
- Volunteers
- 1,024 people
- Sponsor
- University of Kansas Medical Center
Guidelines, Diabetes Mellitus Type 2
Adherence to Clinical Guidelines for Management of Patients With Type 2 Diabetes Mellitus and Obesity
Observational study in physicians regarding their adherence to clinical guidelines (by American Diabetes Association 2025) for the management of type 2 diabetes mellitus and obesity via questionnaire
- Conditions
- Guidelines, Diabetes Mellitus Type 2, Obesity Type 2 Diabetes Mellitus, Obesity (BMI > 35) and Diabetes Mellitus
- Trial name
- NCT07839546
- Testing
- Questionnaire regarding the adherence to American Diabetes Association
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Obesity, PreDiabetes
Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk
Intermittent fasting is a method of restricting calories over a defined period of time and includes regimens such as whole-day fasting, alternate-day fasting, and time-restricted feeding.
- Conditions
- Obesity, PreDiabetes, Diabetes, Hypertension
- Trial name
- NCT05309057
- Testing
- Intermittent Fasting
- Where
- 2 sites in Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Opioid Use
Nudging Providers to Curtail Dangerous Opioid Prescribing: A Trial to Investigate Mechanisms
Despite an enormous policy response, opioid prescribing remains well above historical levels and harms from opioids continue to mount.
- Trial name
- NCT04628832
- Testing
- PMP Use Mandate Letter, Prescribing Information Letter, Prescribing Information + PMP Use Mandate Letter
- Where
- 2 sites in United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes, Prediabetes
Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios and walnuts) are an important source of unsaturated fatty acids, vegetable protein, and fibre, as well as minerals, vitamins, and…
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01630980
- Testing
- Tree nuts
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Dyslipidemia, Diabetes
Meta-analyses of Dietary Pulses and Cardiometabolic Risk
Dietary pulses, more commonly known as "legumes", are generally recognized as healthy components of the diet. Canada's Food Guide encourages consumptions of meat alternatives, such as beans "more often"; and the dietary…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01594567
- Testing
- Dietary pulses
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Cardiovascular Diseases, Coronary Heart Disease
Meta-analysis of Oat Fiber and Cardiovascular Risk Reduction
Oat fibre has been shown to lower cholesterol and may have cardioprotective effects. However, whether this translates to actual cardiovascular risk reduction is unclear, as there is a lack of controlled human trials.
- Trial name
- NCT05171283
- Testing
- Oats or Oat Fibre
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Breastfeeding
Implementation Strategy for a Breastfeeding Guideline in Primary Care
The purpose of this study is to determine whether an implementation strategy for a breastfeeding guide is more effective than the usual practice (simple circulation of the guide) in terms of increasing the percentage of children…
- Trial name
- NCT01474096
- Testing
- implementation strategy of Breastfeeding
- Where
- Spain
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Noninvasive Ventilation
Development, Implementation and Evaluation of a Clinical Practice Guideline for Care of Preterm Infants Receiving Non-invasive Ventilation (NIV)
Non-invasive ventilation (NIV) is increasingly used for supporting preterm infants with respiratory distress in the Neonatal Intensive Care Unit (NICU), and the incidence for nasal injury including skin redness or breakdown…
- Trial name
- NCT04165382
- Testing
- Interventions in the guideline to infants receiving NIV, Usual care to infants receiving NIV
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong
Overweight, Obesity
Network Meta-analyses of Artificially Sweetened Beverages and Cardiometabolic Risk
Sugars especially in form or sugar-sweetened beverages (SSBs) have been singled out as one of the prime culprits in the dual epidemics of obesity and diabetes.
- Trial name
- NCT02879500
- Testing
- Diet beverages
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases
There is an urgent need for stronger evidence to support recommendations for the role of sugars in diabetes and related cardiometabolic diseases.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Hypertension, Cardiovascular Diseases
- Trial name
- NCT02702375
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dyslipidemia, Diabetes
Meta-analyses of Fructose and Cardiometabolic Risk
Diabetes and heart associations continue to discourage high intakes of dietary fructose, a constituent part of the sucrose molecule that is found in fruits and vegetables as a natural sugar and in some processed foods and…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01363791
- Testing
- Dietary fructose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Cardiovascular Disease, Diabetes
Meta-Analyses of Low-risk Lifestyle Behaviours and Patient Important Outcomes
Public health policy is universal in recommending the adoption of low risk low-risk lifestyle behaviors for health promotion and prevention of chronic or non-communicable diseases (NCDs).These behaviors generally include…
- Conditions
- Cardiovascular Disease, Diabetes, Cancer, Mortality
- Trial name
- NCT03234101
- Testing
- Low-risk lifestyle behaviours
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ventilator Associated Pneumonia
Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia
The purpose of this prospective, multicentre, time-series study is to develop, implement, refine, and evaluate a sustainable behaviour change strategy in the intensive care unit (ICU).
- Trial name
- ABATEVAP (NCT00434460)
- Testing
- Education
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,320 people
- Sponsor
- Canadian Critical Care Trials Group
Body Weight, Obesity
Meta-analyses of Food Sources of Fructose-Containing Sugars and Obesity
Sugars have been implicated in the epidemics of overweight and obesity. This view is supported by lower quality evidence from ecological observations, animal models, and select human trials.
- Conditions
- Body Weight, Obesity, Overweight, Adiposity
- Trial name
- NCT02558920
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Overweight, Obesity
Meta-analysis of Fructose-Containing Sugar Sweetened Beverages (SSBs) and Weight Change
Since uncontrolled observational studies first linked fructose to the epidemic of obesity almost a decade ago, it has become a focus of intense concern regarding its role in the obesity epidemic.
- Conditions
- Overweight, Obesity, Diabetes, Prediabetes
- Trial name
- NCT01608607
- Testing
- Fructose-containing sugar sweetened beverages
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Guideline Implementation, Physiotherapy
Physiotherapy Practice in Flemish Nursing Homes
The goal of this observational study is to evaluate the extent to which physiotherapy sessions in Flemish nursing homes adhere to the IAGG-GARN guidelines and to explore factors influencing clinical practice among…
- Conditions
- Guideline Implementation, Physiotherapy, Nursing Homes, Focus Group
- Trial name
- NCT07576751
- Testing
- Mapping therapy sessions
- Where
- 4 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Smoking Cessation
ISTAPS: A Stepped Primary Care Smoking Cessation Intervention
Primary care centers can play a very important role in helping people to stop smoking. There is a large body of research on the effectiveness of specific interventions especially addressed to people who want to stop smoking.
- Trial name
- NCT00125905
- Testing
- Advice, Motivational Interviewing, Nicotine Gum and Patch
- Where
- Spain
- Volunteers
- 3,012 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina