Clinical trials: Clinical Trial
Bipolar Disorder
Risperidone and Divalproex Sodium With MRI Assessment in Pediatric Bipolar
The study is to examine the null hypothesis that risperidone and divalproex sodium are equally effective in treating/stabilizing pediatric bipolar disorder.
- Trial name
- NCT00176202
- Testing
- Divalproex Sodium, risperidone
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Illinois Chicago
Type 1 Diabetes
Primary Intervention With Mucosal Insulin
A dose with proven drug bioavailability to the immune system for use in a phase II/III primary T1DM (type 1 diabetes) vaccination trial (POINT study) in genetically at risk subjects.
- Trial name
- Pre-POINT (NCT02620553)
- Testing
- Human Insulin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Growth Hormone Therapy, Infant, Small for Gestational Age
Neuromuscular Changes In Small For Gestational Age Children During Somatropin Therapy
The planned study focuses on the effect of a one year Somatropin treatment (0.035 mg/kg/d or 0.067 mg/kg/d) in short children born SGA on neuromuscular function and cognitive performance.
- Trial name
- SGA-POWER (NCT00625872)
- Testing
- Somatropin
- Where
- 10 sites in Germany
- Volunteers
- 23 people
- Sponsor
- Pfizer
Bronchopulmonary Dysplasia
Efficacy and Safety Evaluation of Pneumostem® Versus a Control Group for Treatment of BPD in Premature Infants
The objective of this study is to evaluate the efficacy and safety of a single intratracheal administration of Pneumostem® for treatment of Bronchopulmonary Dysplasia (BPD) in high-risk premature infants by comparing…
- Trial name
- NCT01828957
- Testing
- Pneumostem®, Normal Saline
- Where
- 2 sites in South Korea
- Volunteers
- 69 people
- Sponsor
- Medipost Co Ltd.
Complicated Intra-Abdominal Infection
MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)
This study aims to evaluate the safety and tolerability of MK-7625A (ceftolozane/tazobactam) plus metronidazole, compared with that of meropenem in pediatric participants with cIAI.
- Trial name
- NCT03217136
- Testing
- Ceftolozane/Tazobactam, Metronidazole, Meropenem
- Where
- 50 sites in United States, Brazil and 10 more
- Volunteers
- 94 people
- Sponsor
- Merck Sharp & Dohme LLC
Breast Neoplasms
Assessment of Safety and Efficacy of Estetrol in Postmenopausal Women With Advanced Estrogen Receptor Positive (ER+) Breast Cancer
This is a multi-center, open-label, phase I/IIa trial, dose-escalation study with a 3 + 3 cohort design to determine the recommended dose of estetrol for the treatment of patients with advanced breast cancer.
- Trial name
- NCT02718144
- Testing
- Estetrol
- Where
- 2 sites in Germany
- Volunteers
- 12 people
- Sponsor
- Pantarhei Oncology B.V.
Anemia, Iron-Deficiency, Cognitive Performance
Iron-fortified Lentils to Improve Iron (Fe) Status in Bangladesh
We designed a double-blind, community-based, cluster-randomized control trial which will test to establish novel evidence on the efficacy of iron-fortified lentil in improving body Fe status of non-pregnant adolescents in rural…
- Conditions
- Anemia, Iron-Deficiency, Cognitive Performance, Iron-deficiency
- Trial name
- NCT03516734
- Testing
- Iron fortified lentils, Non Iron-fortified lentils, Usual Intake
- Where
- Bangladesh
- Volunteers
- 1,252 people, healthy volunteers welcome
- Sponsor
- Carol Henry
Hereditary Angioedema
PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial
This is a multicenter pharmacokinetic (PK) subtrial to investigate the PK profile of KVD900 (sebetralstat) in adolescent patients 12 to 17 years of age with Hereditary Angioedema (HAE) type I or II.
- Trial name
- NCT05511922
- Testing
- KVD900 600 mg, Drug: KVD900 300 mg
- Where
- 61 sites in United States, Australia and 15 more
- Volunteers
- 11 people
- Sponsor
- KalVista Pharmaceuticals, Ltd.
Preterm Neonates, Venipuncture
Effects of Fetal Positioning During Venipuncture
The study was aimed to examine the effects of fetal positioning during venipuncture on the neonates' pain score and physiological parameters (heart rate, blood-oxygen saturation, body temperature, crying duration) in neonatal…
- Trial name
- NCT06173622
- Testing
- Fetal Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Infant, Small for Gestational Age
Growth Hormone Treatment in Short Children Born Small for Gestational Age
Comparison of 2 different doses of human growth hormone treatment on change in height after 1 and 2 years of treatment.
- Trial name
- NCT00191529
- Testing
- somatropin
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Eli Lilly and Company
Alzheimer Disease
Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial (LAPSE)
Patients with Alzheimer's disease (AD) are increasingly recognized to have seizures in addition to cognitive decline. Seizures may contribute to memory problems as well as other symptoms common in AD like agitation, depression…
- Trial name
- LAPSE (NCT04004702)
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Walter Reed National Military Medical Center
Bronchioloalveolar Cell Variant of Non-small Cell Lung Cancer
Ph II OSI-774 (Erlotinib,Tarceva) In Advanced Bronchioloalveolar Cell Lung Cancer
The primary objective of this study is to determine the major objective response rate of OSI-774 in participants with unresectable or metastatic bronchioloalveolar cell variant of non-small cell lung cancer.
- Trial name
- NCT00590902
- Testing
- OSI-774: erlotinib, TarcevaTM
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Oral Cavity Carcinoma
Behavior Changing Intervention for Smokeless Tobacco and Betel Quid Use in Adolescents
Smokeless tobacco (SLT) is a known risk factor for Oral, Pharyngeal and Esophageal carcinoma. Three-quarters global SLT consumption is among the South Asian Population.
- Trial name
- NCT03488095
- Testing
- BCI for SLT and BQ Use in Adolescents: A CRT
- Where
- Pakistan
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Otitis Media Effusion
Balloon Dilation of Eustachian Tube Versus Tympanostomy Tube in Management of Pediatric Obstructive Eustachian Tube Dysfunction
The study was conducted in children with otitis media with effusionto compare the efficacy and outcome of Balloon dilation of Eustachian tube versus tympanostomy tube .
- Trial name
- NCT07899177
- Testing
- eustachian tube dilatation, tympanostomy tube insertion
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Mansoura University
Health Knowledge, Attitudes, Practices
The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting
Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development.
- Trial name
- STF RCT (NCT07711301)
- Testing
- Science Tooth Fairy Narrative, Cavities vs. Toothpaste, book by Didi Dragon
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Atopic Dermatitis
Delgocitinib Cream for the Treatment of Moderate to Severe Atopic Dermatitis During 8 Weeks in Adults, Adolescents, and Children
This is a multi-center, open-label trial to evaluate safety and pharmacokinetics of topical delgocitinib cream applied to pediatric subjects (2-17 years) and adult subjects (18 years and above) with atopic dermatitis.
- Trial name
- NCT03826901
- Testing
- delgocitinib
- Where
- 16 sites in United States, Canada
- Volunteers
- 46 people
- Sponsor
- LEO Pharma
Kidney Transplantation in Highly Sensitized Patients
Imlifidase Prior to Kidney Transplant in Highly Sensitised Children
The goal of this clinical trial is to learn about the efficacy and safety of imlifidase in highly sensitized paediatric patients, 1-17 years old, with end stage renal disease (ESRD).
- Trial name
- DINKY (NCT05753930)
- Testing
- Imlifidase
- Where
- 6 sites in Finland, France and 3 more
- Volunteers
- 10 people
- Sponsor
- Hansa Biopharma AB
Meningitis, Meningococcal
Study of NeisVac-C Vaccine to Evaluate Immunological Interference With Hepatitis B, Inactivated Polio and Acellular Pertussis Vaccines in Healthy Infants
The primary aim of the study is to show that NeisVac-C does not influence the seroconversion rates induced by hepatitis B (Hep B), inactivated polio (IPV) and acellular pertussis (aP) vaccines in infants.
- Trial name
- NCT00161928
- Testing
- Group C Meningococcal Polysaccharide-Tetanus Toxoid Conjugate Vaccine (GCMP-TT)
- Where
- 14 sites in Austria, Germany
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Pfizer
Rhinitis, Rhinoconjunctivitis
Dose Finding for the Treatment of Rhinitis/Rhinoconjunctivitis Against Mite Allergy
The purpose of the study is to evaluate the more efficient dose for the treatment of rhinitis/rhinoconjunctivitis against mite allergy
- Trial name
- MM09 (NCT02661854)
- Testing
- MM09 Mannosylated 5.000 subcutaneous, MM09 Mannosylated 10.000 subcutaneous, MM09 Mannosylated 30.000 subcutaneous
- Where
- 14 sites in Spain
- Volunteers
- 186 people
- Sponsor
- Inmunotek S.L.
Pneumonia Childhood
Effectiveness Trial of Day-care vs. Usual Care of Severe Pneumonia & Malnutrition in Children
Background: At present pneumonia and malnutrition have become the leading causes of mortality among <5-year-old children in developing countries.
- Trial name
- Day-care (NCT02669654)
- Testing
- Day-care management of Severe Pneumonia
- Where
- 2 sites in Bangladesh
- Volunteers
- 4,000 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.