Clinical trials: Cochlear Implant
Hearing Loss, Unilateral, Deafness, Unilateral
Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness
The aim of the study is to assess the continued efficacy and safety of cochlear implantation in participants aged 5 years and above with Unilateral Hearing Loss (UHL)/Single Sided Deafness (SSD) supporting a change indication for…
- Trial name
- PAS-SSD (NCT05318417)
- Testing
- The Cochlear™ Nucleus® Cochlear Implant (CI) System
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cochlear
Sensorineural Hearing Loss
Objective Measures in Cochlear Implant
One of the main factors affecting the ability to maximize the full potential of a cochlear implant is an accurate map.The goal of mapping is to enable cochlear implant recipients to perceive a desired range of acoustic signals.
- Trial name
- NCT03260374
- Testing
- Electric compound action potential, electric stapedial reflex threshold, electric auditory brain stem response
- Volunteers
- 30 people
- Sponsor
- Assiut University
Hearing Loss, Sensorineural
Clinical Evaluation of the Cochlear Nucleus CI532 Cochlear Implant in Adults
The purpose of this study is to gather long-term data on the FDA approved CI532 cochlear implant, and CP1000 (Nucleus 7) sound processor
- Trial name
- SME (NCT03007472)
- Testing
- CI532, Nucleus 7
- Where
- 10 sites in United States
- Volunteers
- 96 people
- Sponsor
- Cochlear
Inner Ear Malformations
A New Cochlear Implant Electrode For Inner Ear Malformations
The custom made device was produced by Med-El Company. It has a "cork" like stopper instead of the usual silicon ring to prevent gusher. There are two types of electrodes consisting of different length.
- Trial name
- NCT02011867
- Testing
- Cork Electrode
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Deafness
Restauration of the Auditory and Cognitive Functions in Cochlear Implanted Deaf Children in fNIRS
The principal aim of this study is to evaluate the cortical developement of perceptual skills and executive functions over time, in children with cochlear implants aged 10-24 months and 3-7 years compared with normally hearing…
- Trial name
- HearCog (NCT04495660)
- Testing
- Near InfraRed Spectroscopy (fNIRS), Passive perceptual stimulation, Task A not B
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Toulouse
Cochlear Prosthesis Implantation
Electrocochleography Along Cochlear Implant Auditory Rehabilitation
Electrocochleography (eCochG) is an electrophysiological measurement to evaluate the activity of cochlear hair cells in response to acoustic stimulation.
- Trial name
- eCochGIC (NCT04561388)
- Testing
- Electrocochleography, Pure Tone Audiometry, Speech audiometry
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Developmental Cochlear Nerve Deficiency, Acquired Cochlear Nerve Deficiency
Auditory Brainstem Implantation in Young Children
To purpose of this feasibility study is to demonstrate the safety and efficacy of the Nucleus 24 Multichannel Auditory Brainstem Implant (ABI, Cochlear Corp, Sydney, AUS) in children without the diagnosis of neurofibromatosis…
- Conditions
- Developmental Cochlear Nerve Deficiency, Acquired Cochlear Nerve Deficiency, Cochlear Aplasia, Post-meningitis Cochlear Ossification
- Trial name
- NCT01904448
- Testing
- Auditory Brainstem Implantation in Children
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Severe Unilateral Sensorineural Hearing Loss
Cochlear Implantation Among Adults and Older Children With Unilateral or Asymmetric Hearing Loss
Do adults and children over 7 years of age with unilateral or assymetric hearing loss benefit from cochlear implantation on the worst hearing side.
- Trial name
- CI and SSD (NCT02105441)
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Cochlear Implant Listeners
Pediatric Cochlear Implant Remote Programming and Assessment
This is a prospective, interventional study to evaluate efficacy and end user satisfaction of remote cochlear implant programming in the pediatric population.
- Trial name
- NCT07035873
- Testing
- Remote Programming, Remote Speech Perception
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Nationwide Children's Hospital
Vestibular Abnormality
Vestibular Cochlear Implant Hearing Impaired Child
Cochlear implantation (CI) is a well-known surgical procedure to rehabilitate patients with severe to profound sensorineural hearing loss. Indications for this surgery have expanded in the last 10 years including bilateral CI.
- Trial name
- NCT03599804
- Volunteers
- 40 people
- Sponsor
- Assiut University
Cochlear Nerve Disease
Longitudinal Study Of The Evoked Compound Action Potential Measured In Children Cochlear Implant Users
Introduction: In Cochlear Implant (CI) users, the recording of the electrically evoked compound action potential (ECAP) of the auditory nerve represents an option to assess changes in auditory nerve responses and the interaction…
- Trial name
- ECAP (NCT00725998)
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hearing Loss
Sound Processing Innovations in Adult and Paediatric Cochlear Implant Recipients.
This is a feasibility, prospective with sequential enrolment, multicenter, clinical investigation in adults and paediatrics with a CE approved Nucleus cochlear implant. Subjects older than 5 years will be included.
- Trial name
- NCT05476328
- Testing
- SPACE, OPAL-SPACE, ACE
- Where
- 5 sites in Australia, Belgium
- Volunteers
- 8 people
- Sponsor
- Cochlear
Performance Prediction
Cochlear-Implant-Performance-Prediction
Despite improved technology, many cochlear implant (CI) recipients still struggle to understand speech in noise (SIN). Because the bottom-up acoustic signal generated by the implant is distorted relative to normal-hearing…
- Trial name
- NCT07564388
- Testing
- cochlear implant user performance prediction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Bilateral Sensorineural Hearing Loss, Cochlear Implant
Binaural Cue Sensitivity in Children and Adults With Combined Electric and Acoustic Stimulation
There is a rapidly growing population of adult and pediatric cochlear implant (CI) recipients with acoustic hearing preservation in the implanted ear(s) allowing for combined Electric and binaural Acoustic Stimulation (EAS).
- Conditions
- Bilateral Sensorineural Hearing Loss, Cochlear Implant, Hearing Preservation, Electric and Acoustic Simulation
- Trial name
- NCT07356128
- Testing
- binaural processing over time, binaural processing over time for children and adults with normal hearing
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hearts for Hearing
Speech Cortex Disorder
Preoperative Variables Affecting Outcome Of Cochlear Implant
Cochlear implants (CIs) represent one of the most important achievements of modern medicine as, for the first time in history, an electronic device is able to restore a lost sense - hearing.
- Trial name
- NCT03719963
- Testing
- Cochlear implant
- Volunteers
- 40 people
- Sponsor
- Assiut University
Sensorineural Hearing Loss, Enlarged Vestibular Aqueduct
Genotype-phenotype Correlation of SLC26A4 in CI Patients With EVA
To explore the genotype-phenotype correlation of SLC26A4 mutations in cochlear-implanted patients with enlarged vestibular aqueduct.
- Trial name
- NCT04934605
- Testing
- Cochlear implantation
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Otolaryngological Diseases Requiring Mastoidectomy, Middle Ear Surgery, Endolymphatic Sac Surgery, Cochlear Implant, Labyrinthectomy, Petrous Apex Lesions, Facial Nerve Surgery, and Lateral Skull Base Tumors
AI Recognition of Important Structures in Otolaryngological Surgery
Developing a system for artificial intelligence to recognize anatomical landmarks in otolaryngological surgery, enabling real-time tracking of critical temporal bone structures during surgery.
- Trial name
- NCT06726551
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Severe to Profound Prelingual Hearing Loss
Language Development in Children With Cochlear Implants and Speech-language Therapy Interventions
Cochlear implantation is currently offered to children with severe to profound prelingual hearing loss for whom hearing aids alone are insufficient to provide access to oral language (HAS, 2009).
- Trial name
- ICORTHO (NCT07447427)
- Testing
- Speech-language therapy (observed standard care)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deafness
Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces
Despite the success of cochlear implants, devices surgically placed in the inner ears of patients with severe hearing loss, there remains substantial variability in the overall speech perception outcomes for the children and…
- Trial name
- NCT05867173
- Testing
- Experimental Speech Processing Strategy
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Cochlear Hearing Loss
Retrospective Analysis of Speech Performance Using the HiRes Ultra and HiRes Ultra 3D Cochlear Implant
This is a retrospective study designed to collect speech perception results for HiRes Ultra CI and HiRes Ultra 3D CI users as measured in the clinical routine and to confirm the performance of these devices.
- Trial name
- NCT06301581
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Advanced Bionics AG