Clinical trials: Cognition - Other
Schizophrenia, Cognitive Impairment
From Brain Currents to Interpersonal Flow: Investigating the Social Processing Stream of Schizophrenia
The overall objective of this project is to identify the neural signature of the impaired ability to relate socially seen in individuals with schizophrenia.
- Conditions
- Schizophrenia, Cognitive Impairment, Social Competence
- Trial name
- ecoval (NCT03543553)
- Testing
- This is not an intervention study
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Healthy, Healthy Volunteer
Effect of Transcranial Magnetic Stimulation on Memory
This study will examine the effect of transcranial magnetic stimulation (TMS) on short-term memory in healthy adults. Healthy people use their brains to answer short-term memory questions in a different way than do patients with…
- Conditions
- Healthy, Healthy Volunteer, HV
- Trial name
- NCT00105118
- Testing
- Magstim Super Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cognitive Function 1, Social
Social Cognition Assessment in Young Adults
The primary objective of this study is to determine the efficacy and feasibility of a battery of neuropsychological measures evaluating social cognition and behavior in young adults diagnosed with schizophrenia, autism spectrum…
- Trial name
- NCT02922400
- Testing
- Social Cognition Assessment and Training
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Schizophrenia, Psychotic Disorders
Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: 1-year Follow-up
Cognitive enhancement is a primary goal in treating individuals with schizophrenia. Cognitive deficits are already present at the first break of the illness, seem to remain stable during early phases and noticeably influence…
- Trial name
- PAFIP2_nc1Y (NCT02534363)
- Testing
- Aripiprazole, Quetiapine, Ziprasidone
- Where
- Spain
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Fundación Marques de Valdecilla
Schizophrenia, Psychotic Disorders
Dimensional and Developmental Profiles of Psychosis in Children and Adolescents
Five collaborating sites in France will study the broad spectrum of schizophrenia in children and adolescents. Patients will be studied with diagnostic interviews, developmental histories, dimensional clinical ratings…
- Trial name
- PSYDEV (NCT04370730)
- Testing
- clinical, neuroimaging and DNA assessments
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Schizophrenia
Cognitive Enhancement Therapy for Early-Stage Schizophrenia
This study will determine the effectiveness of cognitive enhancement therapy (CET) in treating cognitive abnormalities in people experiencing the early stages of schizophrenia.
- Trial name
- NCT00167362
- Testing
- Cognitive enhancement therapy (CET), Enriched supportive therapy (EST)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Schizophrenia, Autistic Disorder
Exploration of the Social Cognition in Adolescents With a Dissociative Disorder or Autism Spectrum
The schizophrenic disorders and pervasive developmental disorders are neurodevelopmental disorders distinct origin who share common challenges to engage and maintain social relationships and mutual disturbances of affective…
- Trial name
- NCT01805128
- Testing
- Facial recognition of emotions, understanding metaphors, Attribution of intentionality to others in social situations depending on the type of situation
- Where
- 3 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cognition - Other
Cognition Intervention Study Dortmund
Major aim of this study is to add scientifically proven insights into cognitive effects of meals to the existing recommendations for school meals in Germany.
- Trial name
- CogniDO (NCT01401153)
- Testing
- Skipping lunch
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Research Institute of Child Nutrition, Dortmund
Schizophrenia
Training-induced Cerebral Reorganization in Schizophrenia
The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.
- Trial name
- NCT00695708
- Testing
- Brain Fitness Program, Cogpack
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Dementia With Lewy Bodies (DLB), Mild Cognitive Impairment (MCI)
Dementia With Lewy Bodies: Clinical Symptoms, Biomarkers and Progression
The goal of this observational study is to improve the detection of dementia with Lewy bodies (DLB) and its prodromal phases, as well as advancing our current understanding of biological mechanisms and therapeutic options.
- Conditions
- Dementia With Lewy Bodies (DLB), Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Other Dementias
- Trial name
- Find-DLB (NCT07629349)
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Schizophrenia
Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia
This study will use single photon emission computed tomography (SPECT) to study brain nicotine receptors (proteins on the surface of brain cells) in healthy subjects and in patients with schizophrenia.
- Trial name
- NCT00061789
- Testing
- SPECT Imaging of Nicotinic Acetylcholine Receptors in Brain
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Brain Injury, Dementia
Neuropsychiatric Evaluation of Healthy Volunteers and Adults With Schizophrenia
The purpose of this study is to evaluate the cognitive processes of participants with schizophrenia, participants with nervous system and mental disorders, and healthy volunteers.
- Conditions
- Brain Injury, Dementia, Healthy, Mental Disorder
- Trial name
- NCT00001323
- Where
- United States
- Volunteers
- 810 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia
Oculomotor and Spatial Cognition Deficits in Schizophrenia
DESCRIPTION: (Verbatim from the Applicant's Abstract) Abnormalities of eye movement control and spatial cognition are well-established deficits in schizophrenia.
- Trial name
- NCT00931996
- Testing
- Antipsychotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Schizophrenia, Psychotic Disorders
Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: 3-years Follow-up
Cognitive enhancement is a primary goal in treating individuals with schizophrenia. Cognitive deficits are already present at the first break of the illness, seem to remain stable during early phases and noticeably influence…
- Conditions
- Schizophrenia, Psychotic Disorders, Psychosis
- Trial name
- PAFIP3_nc3Y (NCT03883204)
- Testing
- Aripiprazole, Risperidone
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Fundación Marques de Valdecilla
Psychotic Disorders, Cannabis Use Disorder
Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
Cognitive impairment is well established in people with psychosis and is associated with cannabis use. The current study will investigate the neurobiological basis of cognitive change associated with 28-days of cannabis…
- Conditions
- Psychotic Disorders, Cannabis Use Disorder, Cannabis Dependence, Cannabis Use
- Trial name
- NCT05445180
- Testing
- Contingency management
- Where
- Canada
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Cognition - Other
PANDA (Pediatric Anesthesia & NeuroDevelopment Assessment) Study
The purpose of this study is to determine whether the use of anesthetic agents in infants and children have long term adverse effects on neurocognitive development.
- Trial name
- NCT00881764
- Testing
- Inguinal hernia surgery, General anesthesia
- Where
- 4 sites in United States
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Columbia University
Schizophrenia
Social Cognition in Youth Who Have a First Degree Relative With Schizophrenia
Social cognition is an individual's ability to perceive, process, understand, and react to other individuals in a social situation.
- Trial name
- NCT04681807
- Testing
- Emotion Recognition Training, Control Training
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- The Royal Ottawa Mental Health Centre
Early-onset Schizophrenia, Psychotic Disorders
Computerized Cognitive Remediation Therapy in Adolescents With a First Psychotic Episode
Cognitive deficits (CD) are considered one of the essential characteristics in psychotic disorders and occur throughout the course of the disease, being a key characteristic in the evolution of the disease and in the…
- Conditions
- Early-onset Schizophrenia, Psychotic Disorders, Cognitive Remediation Therapy, Cognition
- Trial name
- CCRT2019 (NCT05405946)
- Testing
- Computerized Cognitive Remediation Therapy, Treatment as Usual
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Stress, Complete Psychological Check Up
Cognition and Health in Adolescents, Mindfulness as Prevention of Stress.
The purpose of this study is to determine whether mindfulness is useful as primary prevention for psychological health in highschool students, primarily related to stress, and whether mindfulness can improve cognitive function.
- Conditions
- Stress, Complete Psychological Check Up, Sleep, Cognition - Other
- Trial name
- CHAMPS (NCT01457222)
- Testing
- Mindfulness intervention, Music relaxation
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Region Skane