Clinical trials: Cognitive Functions
Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder
Study of Cognition and Control in Youths
The purpose of this study is to learn more about the functioning of particular types of regions of the brain, specifically, those related to externalizing disorders such as Attention Deficit Hyperactivity Disorder (ADHD)…
- Conditions
- Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder
- Trial name
- NCT03393390
- Testing
- Clinical Assessment Visit, fMRI scan
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Alzheimer Disease, Mini-Mental State Examination
Predictive Factors for Initial MMSE Score and Rapid Decline in Alzheimer's Disease Patients
This study looks at people with Alzheimer's disease to find out which factors are linked to their initial score on the Mini-Mental State Examination (MMSE) and which factors may predict a fast decline in their score over 12…
- Conditions
- Alzheimer Disease, Mini-Mental State Examination, Cognitive Dysfunction, Neuropsychological Tests
- Trial name
- NCT07122856
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier de Gonesse
End Stage Renal Disease
Dehydr8 and Deactiv8
Managing fluid status is a complex but fundamental part of the clinical care of people receiving haemodialysis (HD). Day-to-day fluid management is usually based on the concept of 'target weight' - the weight used to determine…
- Trial name
- NCT03179072
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Portsmouth
Huntington's Disease
Coenzyme Q10 in Huntington's Disease (HD)
The goals of this trial are to determine if coenzyme Q10 is effective in slowing the worsening symptoms of Huntington's disease and to learn about the safety and acceptability of long-term coenzyme Q10 use by determining its…
- Trial name
- 2CARE (NCT00608881)
- Testing
- coenzyme Q10
- Where
- 49 sites in United States, Australia and 1 more
- Volunteers
- 609 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder (ASD)
Cycling Interventions on Cognition in Children With Autism
The goal of this clinical trial was to determine if a specific type of cycling exercise improved executive functions in school-aged children with autism spectrum disorder (both boys and girls, aged 8-10 years, no healthy…
- Trial name
- Cycling&Autism (NCT07295912)
- Testing
- Learning to Bicycle, Bicycle Treadmill, Cycling with Training Wheels
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- Chinese University of Hong Kong
Huntington Disease
Symptomatic Therapy for Patients With Huntington's Disease
Based on the previous symptomatic treatment of Chinese HD patients, this study intends to further optimize the treatment regimen of Chinese HD patients so as to further improve the prognosis of patients.
- Trial name
- NCT04071639
- Testing
- Haloperidol 2Mg Tab, Risperidone 1Mg Tab, Zoloft 50Mg Tablet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vestibular Function, Hearing Loss
Evaluation of Executive Functions in Children With Cochleovestibular Deficit
Vestibular system activity supports many functions ranging from gaze stabilization and postural control to high-level cortical functions involving spatial cognition, body perception, verticality perception, orientation…
- Conditions
- Vestibular Function, Hearing Loss, Cognitive Function, Executive Function
- Trial name
- Vestibulex (NCT05665907)
- Testing
- Questionnaire BRIEF (Behavioral Rating Inventory of Executive Function)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Technology, Cognitive Impairments
Tablet-based Interactive Games in Elderly With Cognitive Impairment and Persons With Intellectual Disability
The study has 10 research questions regarding the cognitive training program and tablet-based interactive games: Primary study questions: 1.
- Conditions
- Technology, Cognitive Impairments, Intellectual Disability
- Trial name
- NCT05822596
- Testing
- Tablet-based interactive games experimental group intervention
- Where
- 5 sites in Hong Kong
- Volunteers
- 68 people
- Sponsor
- The University of Hong Kong
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
The Influence of Electroacupuncture on Postoperative Agitation of Pediatrics Undergoing Sevoflurane General Anesthesia
Postoperative agitation is a common complication in pediatric anesthesia, with an incidence ranging from 10% to 80%. Common surgical procedures in children include tonsillectomy, adenoidectomy, insidious penis prolongation and…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Electroacupuncture
- Trial name
- DZDXEQFWQMSHZD (NCT05924854)
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Down Syndrome
Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome
The aim of this study is to assess the suitability of selected scales (floor/ceiling effects, variability, test-retest reliability) to measure cognitive function in children with Down syndrome over 6 months, and to evaluate the…
- Trial name
- NCT02451657
- Testing
- No Intervention
- Where
- 10 sites in United States, France and 1 more
- Volunteers
- 40 people
- Sponsor
- Hoffmann-La Roche
Physical Disability, Cognitive Dysfunction
Evaluation of mediVR-KAGURA Guided Therapy
The objective is to evaluate mediVR-KAGURA guided therapy for the treatments of physical and cognitive dysfunctions regardless of baseline disease in a prospective interventional design.
- Trial name
- NCT04562662
- Testing
- mediVR KAGURA
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Japan Society of Clinical Research
Cognitive Impairment, Covid19
The MentalPlus® for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19
This study evaluates and rehabilitates the cognitive functions of attention, memory, visual perception, language, and executive by the mentalPlus® digital game of COVID-19 surviving patients after remission of symptoms.
- Conditions
- Cognitive Impairment, Covid19, Cognitive Dysfunction, Depression, Anxiety
- Trial name
- MP-COVID (NCT04632719)
- Testing
- The use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cushing Syndrome
Cognition, Steroids, and Imaging in Cushings Disease
This study investigates the effects of the glucocorticoid hormone cortisol on brain structure and function. Patients with Cushing's disease are studied before and after treatment.
- Trial name
- NCT00081341
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Down Syndrome
The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients
Recovery of the cognitive functions and recovery features after general anaesthesia in Down syndrome patients. A comparison of Sevoflurane and Desflurane.
- Trial name
- NCT02971254
- Testing
- Sevoflurane, Desflurane
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- Asklepieion Voulas General Hospital
Malaria
Early Childhood Malaria Prevention With Maloprim in The Gambia
A trial was conducted in the 1980s to compare two strategies for control of malaria in young children aged 3-59 months: treatment with chloroquine versus treatment combined with fortnightly chemoprophylaxis with Maloprim.
- Trial name
- NCT00294580
- Testing
- Maloprim
- Where
- The Gambia
- Volunteers
- 2,253 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Neurodevelopmental Disorders, Child Behavior Disorders
Impact of General Anesthesia in Childhood on Cognitive Processes
This study aims to evaluate the potential long-term cognitive effects of general anesthesia administered before the age of 4. Specifically, it investigates executive functions-including inhibition, working memory, and cognitive…
- Trial name
- NCT07141797
- Testing
- Executive functions assessment
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
ARFID, Anorexia Nervosa
Cognitive Evaluation of Patients With Eating Disorders
The goal of this cross - sectional observational study is to improve understanding of the psychological and cognitive characteristics of Feeding and Eating Disorders (FEDs), a group of conditions that represent a growing public…
- Conditions
- ARFID, Anorexia Nervosa, Bulimia Nervosa, Cognitive Flexibility
- Trial name
- DNA_ARFID (NCT07478510)
- Testing
- Go/No-go, IAT, WCST
- Where
- 3 sites in Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Brain Stimulation
Family Inclusive Early Brain Stimulation
Social interaction (in the form of serve and return exchanges) between child and parent are crucial for psychosocial, physical and cognitive development.
- Trial name
- FINEBRAINS (NCT02697110)
- Testing
- Edutainment based intervention
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Motor Development, Balance
Balance-Cognitive-Strength Training for Balance, Inhibitory Control, and Gait in Preschool Children
This randomized controlled study evaluated whether an 8-week balance-cognitive-strength training program improved balance ability, inhibitory control, and gait performance in preschool children aged 3 to 6 years.
- Conditions
- Motor Development, Balance, Healthy Children, Gait
- Trial name
- BCS-Preschool (NCT07689474)
- Testing
- Balance-Cognitive-Strength Training
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aiyoudong Children and Youth Sports Health Research Institute
Bipolar Disorder
Reproductive Function in Women With Bipolar Disorder
Many studies have shown that patients with bipolar disorder are prone to reproductive dysfunction, including polycystic ovary syndrome, hyperprolactinemia, and amenorrhea.
- Trial name
- NCT05307848
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
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