Clinical trials: Cold Symptoms
Preterm Delivery, Hypothermia
Randomized Controlled Trial of Social Network Targeting in Honduras
Social network targeting strategies can be used to improve the delivery and uptake of health interventions. We will enroll approximately 30,000 individuals into a randomized controlled trial of different targeting algorithms in…
- Conditions
- Preterm Delivery, Hypothermia, Diarrhea, Upper Respiratory Infection
- Trial name
- NCT02694679
- Testing
- CBNH
- Where
- 2 sites in United States, Honduras
- Volunteers
- 31,195 people, healthy volunteers welcome
- Sponsor
- Yale University
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Intravenous Injections, Vaccination
Efficacy of the Buzzy® Device on the Prevention of Health Care Induced Pediatric Pain in a Vaccination Center
In vaccination centers, venipunctures and vaccinations are sources of pain and anxiety in pediatric patients. Prior painful experiences can reduce the acceptance of later health care, hence making it more difficult for both…
- Trial name
- DOLVAX (NCT03220555)
- Testing
- Buzzy® device, EMLAPATCH (lidocaine, prilocaine)
- Where
- 3 sites in France
- Volunteers
- 220 people
- Sponsor
- Nantes University Hospital
Soccer, Fatigue
Comparison Between Photobiomodulation Therapy (PBMT) and a Cold-Water Immersion (CWI) in Recovery Soccer Player: Analysis of Biochemical Markers of Recovery and Muscular Oxidative Stress.
Competitive soccer engages many of the body's systems to a major extent. The musculoskeletal, nervous, immune and metabolic systems are stressed to a point where recovery strategies post-exercise become influential in preparing…
- Conditions
- Soccer, Fatigue, Oxidative Stress, Recovery
- Trial name
- NCT03593733
- Testing
- Photobiomodulation Therapy, Cold Water Immersion
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- LUCIANA MARIA MALOSA SAMPAIO
Pain
Efficacy of External Cold and a Vibrating Device in Reducing Discomfort of Dental Injections in Children
Children in their seventh year of life (age range of 6 to 7 years) will be included in the study. All children included in the study would have to classified according to the Wright behavior classification as potentially…
- Trial name
- NCT02675387
- Testing
- Buzzy, 2%Lidocaine
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Chronic Tonsillitis, Tonsillectomy
Comparison of Cold Dissection Technique and Needle Monopolar Electrocautery Tonsillectomy
Patients 13-years-or older who undergo tonsillectomy operation (without another additional surgery) will be enrolled in the study.
- Conditions
- Chronic Tonsillitis, Tonsillectomy, Tonsillar Hypertrophy
- Trial name
- TONSIL (NCT02818647)
- Testing
- Tonsillectomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Upper Respiratory Tract Infection (URTI)
Probiotics for Sustained Health
This randomized, double-blind, placebo-controlled pilot study will evaluate the effect of a probiotic supplement on upper respiratory tract infections (URTIs) in children aged 4-18 years with a history of recurrent URTIs.
- Trial name
- NCT07835100
- Testing
- Probiotic
- Where
- 2 sites in Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Acute Cough, Upper Respiratory Tract Infection
Observational Study of SIROPSEDAL in Acute Cough
This prospective, multicenter, observational post-market clinical follow-up study evaluates the performance and safety of SIROPSEDAL in children and adults with acute cough treated in routine clinical practice.
- Conditions
- Acute Cough, Upper Respiratory Tract Infection, Common Cold
- Trial name
- SIROPSEDAL (NCT07625683)
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Laboratoires Elerte
Common Cold, Allergy
Symbiofilm Trial in Allergic Kids (SYMBIOFILM-TAK)
Healsea® Children is a seawater-based nasal spray supplemented with a natural Symbiofilm® extract (0.02%) isolated from marine bacteria.
- Trial name
- NCT05034328
- Testing
- Healsea® Children, Conventional therapies for common cold
- Where
- 15 sites in Poland
- Volunteers
- 186 people
- Sponsor
- Lallemand Pharma AG
Wasting, Undernutrition
Improvement of Nutrition Status, Digestive Conditions, and Upper Respiratory Infections by Using Oral Nutritional Supplementation on Children in Vietnam
Evaluating the efficiency of using the nutrient production toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, anorexia, and upper respiratory infections in children aged 24 - 71 months.
- Conditions
- Wasting, Undernutrition, Malnourished, Malnutrition
- Trial name
- NCT05570045
- Testing
- Colos Gain
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Pain, Fear
Effect Of Distraction Methods On Procedure-Related Fear, Anxiety, And Pain During Intramuscular Injection
Buzzy, shot-blocker, distraction cards, and balloon blowing can reduce fear and pain during the intramuscular intervention in the pediatric emergency service unit.
- Conditions
- Pain, Fear, Anxiety, Child, Only
- Trial name
- NCT04847934
- Testing
- distraction methods
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Cryopyrin-associated Periodic Syndromes, Familial Cold Autoinflammatory Syndrome
Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase
To date there are no approved effective therapies for the treatment of cryopyrin-associated periodic syndromes (CAPS) including Familial Cold Autoinflammatory Syndrome (FCAS), Muckle-Wells Syndrome (MWS), or Neonatal Onset…
- Conditions
- Cryopyrin-associated Periodic Syndromes, Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, Neonatal Onset Multisystem Inflammatory Disease
- Trial name
- NCT00991146
- Testing
- canakinumab
- Where
- 3 sites in Japan
- Volunteers
- 19 people
- Sponsor
- Novartis Pharmaceuticals
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
Fever, Respiratory Tract Infection
The Efficacy and Safety of Dexibuprofen Syrup
The purpose of this study is to compare the safety and efficacy of dexibuprofen syrup and ibuprofen syrup in patients with fever due to common cold.
- Trial name
- NCT00812422
- Testing
- Dexibuprofen, Ibuprofen
- Where
- 4 sites in South Korea
- Volunteers
- 260 people
- Sponsor
- Inje University
Muckle Wells Syndrome
Efficacy, Safety, and Tolerability of ACZ885 in Patients With Muckle-Wells Syndrome
This study is designed to provide efficacy and safety data for ACZ885 (a fully human anti-interleukin-1beta (anti-IL-1beta) monoclonal antibody) administered as an injection subcutaneously (s.c.) in patients with Muckle-Wells…
- Trial name
- REMITTER (NCT00465985)
- Testing
- ACZ885
- Where
- 12 sites in United States, France and 4 more
- Volunteers
- 35 people
- Sponsor
- Novartis
Cryopyrin-associated Periodic Syndromes, Familial Cold Autoinflammatory Syndrome
Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
This trial will provide long-term safety, efficacy and tolerability of ACZ885 in CAPS patients that completed the CACZ885D2307 study
- Conditions
- Cryopyrin-associated Periodic Syndromes, Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, Neonatal Onset Multisystem Inflammatory Disease
- Trial name
- NCT01576367
- Testing
- ACZ885
- Where
- 12 sites in Belgium, Canada and 5 more
- Volunteers
- 17 people
- Sponsor
- Novartis Pharmaceuticals
Cervical Intraepithelial Neoplasia, Papillomavirus Infections
Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL)
High-grade squamous intraepithelial lesions (HSIL), encompassing cervical intraepithelial neoplasia grade 2 (CIN2) with p16 positivity and grade 3 (CIN3), are precancerous conditions that require effective intervention.
- Trial name
- Aurora (NCT07669363)
- Testing
- Loop Electrosurgical Excision Procedure (LEEP) or Cold Knife Conization (CKC), HAL 5% with illumination
- Where
- 28 sites in China
- Volunteers
- 230 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Vaccine, Pain
The Effect of Shotblocker and Cold Massage on Pain, Crying Time and Physiological Parameters in Babies
The aim of this study is to determine the effect of ShotBlocker© and cold massage on pain, crying time and physiological parameters during DaBT-IPA-Hib vaccine administration in 2-6 months old babies.
- Trial name
- NCT05752747
- Testing
- Cold Massage Group, ShotBlocker© Group
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ordu University
Upper Respiratory Infections
Evaluation of Accuracy and Ease of Use of the FilmArray™ Respiratory Panel (RP EZ) in a CLIA-Waived Clinical Setting
The purpose of this study is to assess the accuracy and ease-of-use of a simplified FilmArray Respiratory Panel test (FilmArray RP EZ) when performed according to the manufacturer's instructions by personnel in laboratories…
- Trial name
- NCT02232711
- Where
- 4 sites in United States
- Volunteers
- 1,082 people
- Sponsor
- BioFire Diagnostics, LLC
Wheezing, Upper Respiratory Tract Infections
Nasal Resveratrol and Wheezing Episodes in Preschool Children
As most of the upper airways infections (UAI) leading to wheezing are secondary to viral triggers, the possible antinflammatory and antiviral role of resveratrol has been suggested in several studies, both in vitro and in vivo.
- Trial name
- RSVchild (NCT04689412)
- Testing
- Resveratrol
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Of Perugia