Clinical trials: Colorectal Resection
Cancer of Colon, Surgery
Effect of Music Prehabilitation on Preoperative Anxiety Before Surgery
The goal of this multicenter randomized controlled trial is to investigate the effect of music prehabilitation on preoperative anxiety in patients undergoing elective oncological colorectal resection.
- Conditions
- Cancer of Colon, Surgery, Anxiety
- Trial name
- MU-PRIOR (NCT05982184)
- Testing
- Music
- Where
- 5 sites in Netherlands
- Volunteers
- 116 people
- Sponsor
- Erasmus Medical Center
Colorectal Neoplasms
Using Multimodal Prehabilitation to Improve Outcomes for Frail Patients Undergoing Resection of Colorectal Cancer
The purpose of this study is to determine if a program of physical activity, nutritional supplements and relaxation techniques is effective at decreasing post operative complications in frail colorectal cancer patients undergoing…
- Trial name
- NCT02502760
- Testing
- Physical Exercise Program, Whey Protein Isolate Powder, Relaxation Techniques
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Rectal Cancer
Quality of Life After Abdominoperineal Resection for Rectal Cancer, Comparing Two Surgical Techniques
The purpose of the study is to compare self-reported health related quality of life after two different operating techniques for low rectal cancer operated by rectal amputation, using a specific and detailed questionnaire.
- Trial name
- APR (NCT01323166)
- Testing
- Excision of the levator muscle
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Sahlgrenska University Hospital
Rectal Cancer, Rectal Adenocarcinoma
Factors Predicting Recurrence in Rectal Cancer After Surgery
Colorectal cancer is one of the most frequently diagnosed cancers and a major cause of cancer deaths worldwide. Recurrence after curative surgery is one of the major factors affecting the long-term survival and its frequency is…
- Trial name
- NCT03899870
- Testing
- Rectal resection, Neoadjuvant therapy, Adjuvant therapy
- Volunteers
- 188 people
- Sponsor
- ammar houssem
Colon Cancer, Laparoscopic Colon Surgery
Analysis of Surgical and Oncologic Outcomes After Complete Mesocolic Excision or Non-complete Mesocolic Excision for Right-Sided Colon Cancer
The goal of this observational study is to investigate the efficacy and safety of a modified D3 lymphadenectomy approach compared to Complete Mesocolic Excision (CME) in patients with right-sided colon cancer.
- Conditions
- Colon Cancer, Laparoscopic Colon Surgery, Lymph Node Dissection, Robotic Surgical Procedures
- Trial name
- NCT06684223
- Where
- South Korea
- Volunteers
- 3,787 people
- Sponsor
- Asan Medical Center
Rectal Cancer
Comparison of Low and High Ligation in the Rectal Cancer
The purpose of this study is to evaluate the defecatory function when nerve fibers around the inferior mesenteric artery(IMA) and left colic artery(LCA) are preserved(so called low ligation ) or not(high ligation) in the…
- Trial name
- NCT00701012
- Testing
- preservation of nerve fibers around IMA, resection of nerve fibers around IMA
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Wakayama Medical University
Colorectal Cancer
Real-Time Characterizations of Diminutive Colorectal Polyps Using Narrow Band Imaging
Colorectal cancer is the second leading cause of cancer related death in the United States. Colonoscopy is the most commonly performed screening procedure and diminutive polyps (<5mm) are the most commonly found polyps during…
- Trial name
- NCT02441998
- Testing
- Education intervention: Training in Narrow Band Imaging
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Colorectal Cancer, Colorectal Adenocarcinoma
Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection
Colorectal cancers (CRC) extending beyond the muscularis mucosae and invading the submucosa without extending beyond it are classified as pT1.
- Trial name
- PROMOT1 (NCT06339346)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Colorectal Anastomosis
EAST-west Colorectal Study
Colorectal resection due to benign and malignant diseases is a commonly performed procedure. The continuity of the gastrointestinal tract is re-established by creating an anastomosis.
- Trial name
- EAST-west (NCT05544487)
- Testing
- Colorectal Anastomosis
- Volunteers
- 300 people
- Sponsor
- National and Kapodistrian University of Athens
Colorectal Neoplasms, Gastric Neoplasms
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
Background: Recent advances in cancer research have led to new therapies to treat the disease. It is important to continue these advances and discover new ones. To do that, researchers need tissue samples from solid tumors.
- Conditions
- Colorectal Neoplasms, Gastric Neoplasms, Cholangiocarcinoma, Bile Duct Cancer
- Trial name
- NCT01915225
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- National Cancer Institute (NCI)
Colon Cancer Stage I, Colon Cancer Stage II
Comparison Between Results of 2 Laparoscopic Surgical Procedures in Operable Colon Cancer Cases in Upper Egypt
The investigators will assess and compare Surgical, pathological and oncological outcomes between two laparoscopic procedures conventional colectomy versus complete mesocolic excision for operable colon cancer cases in Upper Egypt
- Trial name
- NCT05421702
- Testing
- laparoscopic conventional colectomy, laparoscopic complete mesocolic excision
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Rectal Neoplasms
Defunctioning Cannula Ileostomy After Lower Anterior Resection of Rectal Cancer
Most surgeons suggest the use of fecal diverting to address the high morbidity and mortality associated with anastomotic leakage (AL) in patients with high risk factors on AL who are undergoing anterior resections.
- Trial name
- NCT01980238
- Testing
- cannula ileostomy, loop ileostomy, LAR
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Colorectal Cancer
Combination Chemotherapy in Treating Patients With Resected Colon Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug is a way to kill more tumor cells.
- Trial name
- NCT00378716
- Testing
- 5-fluorouracil, leucovorin calcium, tegafur
- Volunteers
- 1,608 people
- Sponsor
- NSABP Foundation Inc
Rectal Cancer, Colo-rectal Cancer
Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery
When a patient is diagnosed with a rectal (bowel) polyp or cancer, radiology doctors read MRI scans to describe how deeply the cancer invades into the bowel wall (this is the 'stage' of the cancer).
- Trial name
- PRESERVE (NCT04103372)
- Testing
- MRI scan, Radiologist training
- Where
- 23 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Colon Cancer
International Prospective Observational Cohort Study for Optimal Bowel Resection Extent and Central Radicality for Colon Cancer
The T-REX study aims to clarify the actual status of metastatic lymph node (LN) distribution in colon cancer and provide reliable evidence regarding the optimal length of bowel resection and the extent of central lymph node…
- Trial name
- T-REX (NCT02938481)
- Where
- 36 sites in Germany, Japan and 5 more
- Volunteers
- 3,647 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Metastatic Colorectal Cancer
An Observational Study of Bevacizumab in Chinese Patients With Metastatic Colorectal Cancer
This observational, multicenter, prospective study will evaluate the use of bevacizumab in real clinical practice in chinese patients with metastatic colorectal cancer.
- Trial name
- NCT01860144
- Testing
- Bevacizumab
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Peking University
Single-Port Colorectal Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Colorectal Surgeries（SPiM-RWS-CR）
A real-world study to evaluate the clinical performance and safety of da Vinci SP Surgical System ("SP single-port robot" for short) for single-port robot-assisted colorectal surgeries in the real world, providing a real world…
- Trial name
- NCT06141421
- Testing
- procedure
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Colorectal Carcinoma
Laparoscopic Assisted Versus Open Resection for Colorectal Carcinoma
The aim of the investigators' randomized trial is to compare the short-term clinical outcome and survival between laparoscopic-assisted and open resection of colorectal carcinoma.
- Trial name
- NCT00485316
- Testing
- Laparoscopic assisted resection of colorectal carcinoma
- Where
- China
- Sponsor
- Chinese University of Hong Kong
Rectal Neoplasms, Low Anterior Resection
Use of One Kind of Controllable Tube Ileostomy in the Low Rectal Cancer
Most surgeons suggest the use of fecal diverting to address the high morbidity and mortality associated with anastomotic leakage (AL) in patients with high risk factors on AL who are undergoing low anterior resections(LAR).
- Trial name
- CTI (NCT02012023)
- Testing
- Low anterior resection, tube ileostomy, loop ileostomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Colonic Cancer
Open Versus Laparoscopic Right Hemicolectomy for Right Colon Cancer
The aim of this study is to demonstrate the feasibility, surgical, and oncologic outcomes of laparoscopic right hemicolectomy with CME and CVL compared to open surgery.
- Trial name
- CME (NCT04434508)
- Testing
- laparoscopic right hemicolectomy with CME and central v, Open right hemicolectomy with CME and central v
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University