Clinical trials: Complications
Anemia, Sickle Cell, Sickle Cell Disease
Preventing Sickle Cell Kidney Disease
Untreated hypertension and renal injury are risk factors for increased morbidity and mortality in sickle cell disease, yet early markers of progressive disease have not been identified and therapies to prevent the development of…
- Conditions
- Anemia, Sickle Cell, Sickle Cell Disease, Kidney Disease, Hypertension
- Trial name
- NCT02373241
- Testing
- Losartan
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Ovarian Neoplasms
MRI in Ovarian Tumors
Role of multi paramrtric MRI and MRI perfusion in indetermint ovarian lesions by using ORADS MRI
- Trial name
- NCT05769205
- Testing
- MRI
- Volunteers
- 25 people
- Sponsor
- Assiut University
Chronic Kidney Disease, Chronic Renal Failure
Karolinska Cardiorenal Theme-centre and StockholmHeartbank
Chronic kidney disease (CKD) affects 10-18% of the adult population and is becoming recognized as one of the most serious disorders causing increased risk for cardiovascular disease and death.
- Conditions
- Chronic Kidney Disease, Chronic Renal Failure, Acute Coronary Syndrome, Ischemic Heart Disease
- Trial name
- KKT (NCT01204645)
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Danderyd Hospital
Pain, Postoperative
Quadratus Lumborum Block Versus Caudal Block for Pediatric Postoperative Analgesia
The aim of this study is to compare between two regional analgesic techniques; caudal block and ultrasound guided quadratus lumborum block as regard degree of pain relief, accuracy of block, effect on hemodynamic stability and…
- Trial name
- NCT03646630
- Testing
- Quadratus Lumborum Block, Caudal Block
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Fayoum University Hospital
Endometrial Cancer, Extreme Obesity
Transvaginal Natural Orifice Endoscopic Surgery for Extremely Obese Patients With Early-stage Endometrial Cancer
The aim of this study is to investigate the feasibility and efficacy of the v-NOTES approach for extremely obese patients with early-stage type 1 endometrial cancer.
- Trial name
- NCT04240730
- Testing
- Transvaginal natural orifice endoscopic surgery for endometrial cancer staging
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Liver Fibrosis, Pediatric Disorder
Pediatric Liver Transplantation-Liver Fibrosis Evaluation by Using Fibrosis Panel
Liver transplantation in children is highly successful with >80% having 20 years survival. Most pediatric liver diseases are potentially curable with liver transplantation and it is important to establish whether children who…
- Conditions
- Liver Fibrosis, Pediatric Disorder, Liver Transplant; Complications
- Trial name
- PT-LiFE (NCT05308628)
- Testing
- Liver Allograft Fibrosis by Using Fibrosis Panel(PRO-C3, PIIINP, TIMP-1, HA etc.)
- Where
- 2 sites in China
- Volunteers
- 1,200 people
- Sponsor
- RenJi Hospital
Hypertension, Hypertension, Pregnancy-Induced
The Relaxation and Blood Pressure in Pregnancy (REBIP) Study
Over 10% of women have high blood pressure during their pregnancy which may affect their health or that of their baby. There are currently no methods to prevent most high blood pressure in pregnancy and some treatments are not…
- Conditions
- Hypertension, Hypertension, Pregnancy-Induced, Pre-Eclampsia
- Trial name
- NCT00303173
- Testing
- Guided Imagery
- Where
- 2 sites in Canada
- Volunteers
- 69 people
- Sponsor
- University of Toronto
Infertility and at High Risk of OHSS
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022241
- Testing
- triptorelin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chenshiling
Clotrimazole, Ovulen
Comparative Efficacy of Ovule vs Tablet
The study is focused to prove that the efficacy of a new Canesten formulation (ovule) is not inferior to the old Canesten formulation (tablet)
- Conditions
- Clotrimazole, Ovulen, Vulvovaginal Candidiasis
- Trial name
- NCT00755053
- Testing
- Clotrimazole, vaginal ovule, Clotrimazole, vaginal tablet
- Where
- 17 sites in Germany, Russia
- Volunteers
- 466 people
- Sponsor
- Bayer
X-Linked Hypophosphatemia
A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal Growth
An observational, prospective, mixed-methods study involving the integration of quantitative and qualitative data exploring the lived experience of burosumab-treated adolescents with XLH at the end of skeletal growth.
- Trial name
- NCT05181839
- Testing
- Burosumab
- Where
- 14 sites in France, Germany and 3 more
- Volunteers
- 25 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Neoplasms, Gynecologic
rhTPO Mobilized Auto Cryo Platelets For GYN Patients Receiving Carboplatin
A Pilot Study of Transfusion of rhTPO-Derived Autologous Platelets Cryopreserved with ThromboSol and 2% DMSO in Patients with Gynecologic Malignancy Receiving Carboplatin
- Trial name
- NCT00038012
- Testing
- Thrombopoietin, Platelet-pheresis, Carboplatin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
Stem Cell Transplant Complications
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative therapy for many malignant or nonmalignant hematological diseases.
- Trial name
- NCT04502628
- Testing
- Hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shandong Provincial Hospital
Peritoneal Dialysis
A Multi-center Prospective Cohort Study Based on Peritoneal Dialysis Telemedicine-assisted Platform
Increasing the proportion of patients on peritoneal dialysis (PD) may relieve the financial burden caused by the growing number of patients with end-stage renal disease (ESRD).
- Trial name
- PDTAP (NCT03571451)
- Where
- 27 sites in China
- Volunteers
- 7,000 people
- Sponsor
- Peking University First Hospital
Trauma; Complications, Aspiration
Gastric Ultrasound in Pediatric Trauma Patients
Gastric ultrasound has become increasingly utilized to examine volume and quality of gastric contents in the preoperative setting to guide anesthetic management and relay risk of aspiration in both adult and pediatric medicine.
- Trial name
- NCT05330351
- Testing
- Gastric Ultrasound
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Philadelphia
Acute Pain, Pain, Postoperative
Supraclavicular Blocks for Post-Operative Pain Control in Supracondylar Fracture Fixation, a Retrospective Analysis of Single Shot Catheter Techniques
We hypothesize that patients who receive a supraclavicular block via Angiocath, placed intra-operatively and dosed post-operatively following neurologic examination, will have lower pain scores, lower use of intravenous morphine…
- Trial name
- NCT02210429
- Testing
- Elbow Fracture Fixation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Neuroblastoma, Brain Tumor
Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation
The purpose of this study is to investigate whether the prophylactic use of itraconazole is a better option than empirical use of itraconazole in the management (prevention and treatment) of fungal infection associated with…
- Conditions
- Neuroblastoma, Brain Tumor, Retinoblastoma, Wilms Tumor
- Trial name
- NCT00336531
- Testing
- itraconazole
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Urolithiasis
Extracorporeal Shockwave Lithotripsy, Electroconductive and Electrohydraulic Types
To evaluate the efficacy and safety of electroconductive (EC) and electrohydraulic (EH) extracorporeal shock wave lithotripsy (ESWL) for the treatment of ureter and kidney stones, this study conducted a randomized controlled…
- Trial name
- NCT06144372
- Testing
- Electroconductive and Electrohydraulic types
- Where
- South Korea
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Allogeneic Hematopoietic Stem Cell Transplantation
Prospective Cohort for the Evaluation of Biomarkers Following HCT (BMT CTN 1202)
The goal of this protocol is to establish a cohort of at least 1500 biologic samples collected prospectively from patients treated in BMT CTN centers that will be a shared bio specimen resource for conducting future allogeneic…
- Trial name
- NCT01879072
- Where
- 42 sites in United States
- Volunteers
- 1,860 people
- Sponsor
- Medical College of Wisconsin
Obesity, Childhood, Diabetes Mellitus, Type 2
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort study is a unique and comprehensive longitudinal study of 630 Caucasian children and their parents that was designed to investigate the natural history and…
- Conditions
- Obesity, Childhood, Diabetes Mellitus, Type 2, Cardiovascular Risk Factor, Pediatric ALL
- Trial name
- QUALITY (NCT03356262)
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Infections, Papillomavirus
Post-marketing Safety Study to Assess the Risk of Spontaneous Abortions in Women Exposed to Cervarix Residing in UK
This study will assess the risk of spontaneous abortion during weeks 1-23 and weeks 1-19 of gestation, respectively, and other pregnancy outcomes, in an exposed cohort, i.e.
- Trial name
- NCT01905462
- Testing
- Data Collection, Cervarix
- Where
- United Kingdom
- Volunteers
- 1,046 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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