Clinical trials: Condition
Dysentery, Shigella, Shigellosis
Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery
The purpose of this study is to assess the efficacy of 3 days of azithromycin (AZI) compared to 3 days of ciprofloxacin (CIP) (standard-of-care) for the treatment of children hospitalised with dysentery in Ho Chi Minh City.
- Conditions
- Dysentery, Shigella, Shigellosis, Diarrhea
- Trial name
- CIPAZ (NCT03854929)
- Testing
- Ciprofloxacin, Azithromycin
- Where
- Vietnam
- Volunteers
- 364 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Sturge - Weber Syndrome (SWS)
Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)
Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face.
- Trial name
- NCT00610402
- Testing
- blood sample tear drop sample
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, Irvine
Chronic Kidney Failure
Intravascular Volume Assessment Using Ultrasonography in Pediatrics Renal Transplant: A Prospective Cohort Study
This study is designed for volume assessment in pediatrics during major surgery using non-invasive tools as ultrasonography without the need of invasive techniques avoiding its complications and as a guide for fluid therapy…
- Trial name
- NCT04008953
- Testing
- ultrasonography
- Volunteers
- 16 people
- Sponsor
- Fatma Alzahraa Mohamed Ibrahim Hassan Haggag
Anorexia, Obesity
Estimating the Short-term Effectiveness of Online Advertisements for Improving Health
Bing ads designed to encourage people to adopt healthier practices (e.g., stop smoking, become physically active, stop consuming harmful content) are shown using the advertising system, to test which ads are more effective as…
- Conditions
- Anorexia, Obesity, Smoking Cessation
- Trial name
- NCT03439553
- Testing
- Ads display with target websites, Ads display with control websites
- Where
- Israel
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- Microsoft Research
Pediatrics Nephrology
The Role of Vitamin K2 in Preventing Glucocorticoid-Induced Bone Loss in Children With Nephrotic Syndrome
Long-term glucocorticoids therapy is associated with various complications, including decreased bone strength (Glucocorticoid-induced osteoporosis) and an increased risk of fracture.
- Trial name
- NCT07206537
- Testing
- Vitamin K 2
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Severe Spasticity
Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump
Safety study to assess the 3 mg/mL baclofen injection (intrathecal) using a programmable pump
- Trial name
- NCT01520545
- Testing
- Gablofen® 3 mg/mL (baclofen injection), SynchroMed® II Programmable Pump
- Where
- 13 sites in United States
- Volunteers
- 153 people
- Sponsor
- Piramal Critical Care, Ltd.
Undiagnosed Conditions, Rare Disorders
Gene Discovery Core, The Manton Center
The Gene Discovery Core at The Manton Center for Orphan Disease Research based at Boston Children's Hospital studies families with rare, poorly understood or undiagnosed, but suspected genetic conditions.
- Conditions
- Undiagnosed Conditions, Rare Disorders, Orphan Diseases
- Trial name
- NCT02743845
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Boston Children's Hospital
Diabetes
Study of the Effect of Telemedicine on Glycemic Control for Patients With Diabetes and Treated With Insulin
The purpose of this study is to assess glycemic control changes in insulin-treated patients with diabetes using a continuous glucose monitoring CGM system through the ETAPES telemedicine program.
- Trial name
- TLS-DIAB (NCT04883372)
- Testing
- continuous glucose monitoring
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Sud Francilien
Disability Physical, Brain Injuries
Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Madonna's Rehabilitation Engineering Center of Excellence (REC) is continually developing custom devices for persons with disabilities.
- Conditions
- Disability Physical, Brain Injuries, Stroke, Spinal Cord Injuries
- Trial name
- NCT03567239
- Testing
- Using adaptive device.
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Madonna Rehabilitation Hospital
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Nephrotic Syndrome in Children, Nephrotic Syndrome Steroid-Dependent
Dupilumab Therapy in Nephrotic Syndrome in Children
The goal of this clinical trial is to learn if dupilumab works to treat severe nephrotic syndrome in children. It will also learn about the safety of dupilumab.
- Trial name
- SMART-NS (NCT07091175)
- Testing
- Dupilumab, Co-intervention of Prednisolone wean during randomised controlled phase, Dupilumab open label extension phase
- Where
- 2 sites in Singapore
- Volunteers
- 66 people
- Sponsor
- National University Hospital, Singapore
Autism
Role of Bumetanide in Treatment of Autism
Role of bumetanide in Autism
- Trial name
- NCT04766177
- Testing
- Bumetanide
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sherief Abd-Elsalam
Necrotizing Enterocolitis, Digestive System Abnormalities
Brain Manganese Deposition in High Risk Neonates
Excessive exposure to manganese (Mn) results in Mn deposition in the brain causing adverse neurological effects. Sick infants requiring parenteral nutrition (PN) may be at increased risk of Mn neurotoxicity because neonatal PN…
- Conditions
- Necrotizing Enterocolitis, Digestive System Abnormalities, Cholestasis
- Trial name
- NCT00392977
- Testing
- remove Mn from PN if evidence of increased brain Mn on MRI
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Vanderbilt University
Respiratory Syncytial Virus
A Prospective, Epidemiological Study to Assess the Disease Burden of Respiratory Syncytial Virus Associated, Suspected Lower Respiratory Tract Infections in Newborns, From 0 to 2 Years of Age and Risk of Development of Wheeze and Asthma From 0 to 6 Years of Age
The purpose of this study is to assess the incidence and associated healthcare utilization of RSV-associated, suspected LRTI in a general population of infants from birth up to 2 years of age, and also to assess the accuracy of a…
- Trial name
- NCT01995175
- Testing
- Nasal swab sampling, Blood sampling, Diary cards
- Where
- 23 sites in United States, Argentina and 6 more
- Volunteers
- 2,409 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Recessive Dystrophic Epidermolysis Bullosa
Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis Bullosa
The aim of this clinical trial is to investigate the efficacy (by monitoring overall improvement of EB symptoms) and safety (by monitoring adverse events) of three doses of allo-APZ2-EB administered intravenously to patients with…
- Trial name
- NCT03529877
- Testing
- allo-APZ2-EB
- Where
- 6 sites in United States, Austria and 3 more
- Volunteers
- 16 people
- Sponsor
- RHEACELL GmbH & Co. KG
Obesity, PreDiabetes
Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk
Intermittent fasting is a method of restricting calories over a defined period of time and includes regimens such as whole-day fasting, alternate-day fasting, and time-restricted feeding.
- Conditions
- Obesity, PreDiabetes, Diabetes, Hypertension
- Trial name
- NCT05309057
- Testing
- Intermittent Fasting
- Where
- 2 sites in Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Organophosphate Poisoning
Paraoxonase-1 Pseudo Cholinesterase Organophosphate Toxicity Enzyme in Prediction the Severity and Outcome of Acute Organophosphate Poisoning and Its Correlation With Pseudo Cholinesterase Enzyme Level.
The aim of the present study is to: Evaluate the serum Paraoxonase-1 level in cases with organophosphate compounds poisoning and to correlate it᾿s level with the severity, outcome of acutely organophosphate poisoned cases .
- Trial name
- NCT06108557
- Testing
- Serum Pararoxonase -1 level, Diagnostic Test: Serum pseudocholinesterase enzyme level
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Heart Failure, Congenital Heart Defects
Right Ventricular Failure in Congenital Heart Defects
Usually, "heart failure" refers to myocardial insufficiency of the left ventricle. However, in patients with congenital heart defects, often predominantly the right ventricle is affected.
- Trial name
- NCT00266201
- Where
- 9 sites in Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Competence Network for Congenital Heart Defects
Cerebral Palsy
Effects of Myofascial Release Technique on Upper Limb Functions in Cerebral Palsy
Cerebral palsy (CP) is a common neurodevelopmental disorder characterized by motor impairments, including spasticity, muscle tightness, and limited range of motion in the limbs.
- Trial name
- NCT06198101
- Testing
- Myofascial Release Technique, Myofascial Release Technique along with segmental vibrator
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cystic Fibrosis
Ivacaftor in French Patients With Cystic Fibrosis and a G551D Mutation
The purpose of this study is to determine whether the treatment with Ivacaftor remains effective and safe in the patients with cystic fibrosis (and at least one G551D CFTR mutation) in the real life setting, after the drug has…
- Trial name
- IVACAFTOR1 (NCT02194881)
- Testing
- CF patients with a G551D mutation and treated with Ivacaftor
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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