Clinical trials: Congestion
Common Cold, Nasal Congestion
Two Seawater-based Formulations for Relief of Nasal Congestion in Paediatric Subjects
The objective of this clinical trial is to evaluate the tolerance and efficacy of two Stérimar nasal sprays products in children who have nasal congestion due to the common cold.
- Trial name
- NCT05244148
- Testing
- IP1 - Stérimar BLOCKED NOSE Baby nasal spray, IP2 - Stérimar Stop & Protect Cold Baby + standard of care, Standard of Care
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- Church & Dwight Company, Inc.
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05583)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00728416
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 333 people
- Sponsor
- Organon and Co
Upper Respiratory Tract Infection, Nasal Congestion and Inflammations
Examination of the Effectiveness of Nasal Irrigation Techniques in Infants With Nasal Congestion
The research investigates the effects of high-volume and low-volume nasal irrigation techniques applied to relieve nasal congestion in infants with nasal congestion due to upper respiratory tract infections.
- Trial name
- NCT06002594
- Testing
- group low-volume irrigation, group high-volume irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Obstructive Sleep Apnea, Nasal Congestion
Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure
1. CPAP compliance will be significantly higher in both the heated humidity with Thermosmart™ and the nasal steroid phases compared to the double placebo phase. 2.
- Conditions
- Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
- Trial name
- Thermosmart (NCT00665977)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Clayton Sleep Insititute
Patency, Hepatic Venous Congestion
Usability of Ringed Polytetrafluoroethylene Graft for Venous Vascular Reconstruction of Living Donor Liver Transplantation
Middle hepatic vein (MHV) reconstruction with an interposition vessel graft has been settled as a standard procedure for living donor liver transplantation (LDLT) using a right lobe graft.
- Trial name
- MHVLDLT (NCT01205802)
- Testing
- MHV reconstruction
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Perennial Allergic Rhinitis
Efficacy Study for the Symptomatic Treatment of Perennial Allergic Rhinitis With a 1 Year Safety Extension
Double-blind phase: The objective of the study was to evaluate the efficacy and safety of Bilastine 20 mg, compared to Cetirizine and placebo for the treatment of perennial allergic rhinitis.
- Trial name
- NCT01127620
- Testing
- Bilastine, Cetirizine
- Volunteers
- 650 people
- Sponsor
- Faes Farma, S.A.
Chronic Nasal Congestion, Lung Infection
Biomarker for Cystic Fibrosis
International, multicenter, observational, longitudinal study to identify biomarker/s for Cystic fibrosis and to explore the clinical robustness, specificity, and long-term variability of these biomarker/s
- Conditions
- Chronic Nasal Congestion, Lung Infection, Breathlessness, Clubbing Toes
- Trial name
- BioCyFi (NCT02710383)
- Where
- 5 sites in Albania, Georgia and 3 more
- Volunteers
- 54 people
- Sponsor
- CENTOGENE GmbH Rostock
Pelvic Congestion Syndrome
Endovascular Management of Pelvic Congestion Syndrome
Pelvic congestion syndrome (PCS) is a common cause of chronic pelvic pain in women and is associated with pelvic venous insufficiency.
- Trial name
- PCSIR (NCT07735156)
- Testing
- Endovascular embolization
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Nasal Congestion
To Determine if Diphenhydramine Works for Nasal Congestion at Two Different Doses
The study was to determine if the drug worked to relieve nasal congestion experienced by people with seasonal allergies.
- Trial name
- NCT00648973
- Testing
- Diphenhydramine 50 mg, Diphenhydramine 25 mg, Pseudoephedrine 120 mg
- Where
- 12 sites in United States
- Volunteers
- 1,021 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Pulmonary Congestion, Congenital Heart Disease
Utility of Lung Ultrasound in the Estimation of Extravascular Lung Water in Pediatric Population
Increased extravascular lung water (EVLW) may increase mortality and morbidity in cardiopulmonary pathology. Many factors can cause increased extravascular lung water and pulmonary edema after cardiac surgery.
- Conditions
- Pulmonary Congestion, Congenital Heart Disease, Post-Op Complication
- Trial name
- NCT04417790
- Testing
- Lung ultrasound and EVLW measurement by transpulmonary thermodilution.
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Liver Fibrosis
Development of Novel MRI Methods for Detecting, Discriminating, and Measuring Liver Fibrosis and Congestion in Fontan Patients
In this research study, the investigators will conduct a prospective cross-sectional study of pediatric and adult Fontan patients that will correlate a variety of quantitative MRI biomarkers with histopathologic data.
- Trial name
- NCT03539757
- Testing
- Non-Contrast Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Severe Sepsis, Malaria
Monitoring of Perfusion in Sepsis and Malaria
Sepsis and severe malaria together contribute to an estimated 13 million deaths annually, a great burden of which is in low-income countries.
- Trial name
- PERFuSE (NCT03641534)
- Testing
- Lung Ultrasound examination, Compression ultrasonography (CUS), Echocardiography
- Where
- Bangladesh
- Volunteers
- 103 people
- Sponsor
- University of Oxford
Nasal Congestion Associated With the Common Cold
A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold
This study is designed to confirm the effectiveness of single-ingredient pseudoephedrine in children for the temporary relief of nasal congestion due to the common cold, an indication described under 21 CFR 341.80(b)(1).
- Trial name
- NCT01744106
- Testing
- pseudoephedrine hydrochloride 30 mg tablets
- Where
- 11 sites in United States
- Volunteers
- 565 people
- Sponsor
- Perrigo Company
Covid19 Virus Infection
Medical Herbs Inhibit Inflammation Directing T Cells to Kill the COVID-19 Virus (COVID)
The human immune system is designed to protect individuals from external sources of infection and internal cell mutation. It works effectively and efficiently until inflammation disturbs its functioning.
- Trial name
- COVID (NCT04790240)
- Testing
- Inflammation (I), Inflammation (II), Inflammation (III)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- All Natural Medicine Clinic, LLC