Clinical trials: Conscious Sedation
Dental Anxiety
Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment
The aim of the study is to evaluate the effect of nebulized Midazolam, Dexmedetomidine, and their combination as procedural, moderate sedative agents in preschoolers undergoing dental treatment.
- Trial name
- NCT03827408
- Testing
- Midazolam group (MDZ), Dexmedetomidine group (DEX), Combination of Midazolam and Dexmedetomidine (MDZ/DEX)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Nourhan M.Aly
Conscious Sedation
Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies
The role of Adjunct therapies such as Child Life therapy and Music listening during Procedural Sedation and Analgesia(PSA) for children during painful procedures has not been studied in the Emergency Department (ED).
- Trial name
- NCT02518919
- Testing
- Child life intervention, Music listening
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Children's Hospital of Michigan
Dental Caries
Isolite and Dental Treatment Under Conscious Sedation
Hypothesis The use of Isolite® system does not produce upper airway obstruction in the pediatric population during dental treatment with conscious sedation.
- Trial name
- NCT01683851
- Testing
- Isolite System
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sedation, Conscious
Intranasal Midazolam in Children as a Pre-Operative Sedative
The purpose of this study is to see if adding a numbing medicine, xylocaine, to the nasal midazolam makes giving the midazolam easier and more comfortable without affecting how the midazolam works as a sedative.
- Trial name
- NCT02314546
- Testing
- Midazolam, xylocaine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Bassett Healthcare
Clinical Anxiety, Clinical Cooperation
Comparison of Effect of Nitrous Oxide-Oxygen Conscious Sedation and Cognitive-behavioral Therapy on Children's Anxiety in Dentistry
Visiting anxious and fearful children is an inevitable prospect of the daily work of every dentist who treats pediatric patients.
- Trial name
- NCT02024594
- Testing
- Nitrous Oxide-Oxygen conscious sedation, cognitive-behavioral therapy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Dental Anxiety, Pain
Nitrous Oxide Prior to Intranasal Midazolam for Moderate Dental Sedation in Pediatric Patients
The purpose of this study is to assess the effectiveness of nitrous oxide/oxygen administration in reducing the discomfort of intranasal midazolam administration for moderate sedation for dental procedures.
- Trial name
- NCT04083105
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Colorado
Aortic Stenosis
Association of Type of Anesthetic and Outcomes in Transfemoral Aortic Valve Replacement
This study proposes to perform a descriptive analysis and pilot observational study looking at the types and quantity of anesthetic agents used and their associations with outcomes among patients scheduled to receive transfemoral…
- Trial name
- NCT02786264
- Testing
- Dexmedetomidine with propofol, Propofol
- Volunteers
- 186 people
- Sponsor
- Yale University
Conscious Sedation Failure During Procedure
Ketofol Versus Propofol in Urgent ERCP for Acute Cholangitis
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a lengthy and uncomfortable procedure that requires adequate sedation. Propofol is the commonly used sedative during ERCP.
- Trial name
- NCT04997967
- Testing
- Ketamine/Propofol, Propofol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Respiration, Artificial, Critical Illness
Adjunctive Clonidine in the Sedation of Mechanically Ventilated Children
Almost all critically ill children who are mechanically ventilated require sedation and analgesia. Providing effective sedation for children in the PICU requires careful balancing of the need for sedation with the adverse effects…
- Conditions
- Respiration, Artificial, Critical Illness, Conscious Sedation, Deep Sedation
- Trial name
- NAPS Pilot (NCT00959062)
- Testing
- clonidine
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Hamilton Health Sciences Corporation
Hypoventilation, Hypoxia
Using Capnography to Reduce Hypoxia During Pediatric Sedation
The investigators hypothesize that the addition of capnography during moderate sedation will improve recognition of hypoventilation and apnea.
- Trial name
- NCT01463527
- Testing
- Nellcor NPB-70 Capnograph
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Yale University
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Cerebral Palsy
Conscious Sedation With Nitrous Oxide in Control of Stress During Dental Care for Individuals With Cerebral Palsy
Cerebral Palsy induces oral alterations that impact on oral health, requiring dental treatment. The objective of this study was to evaluate the use of conscious sedation with nitrous oxide (N2O) in the control of stress during…
- Trial name
- NCT02322983
- Testing
- Control of Stress
- Where
- Brazil
- Volunteers
- 77 people
- Sponsor
- Universidade Cruzeiro do Sul
Emergency Department Procedural Sedation, Fracture Reduction
Ketofol vs Propofol for Emergency Department Procedural Sedation and Analgesia
When patients come to the Emergency Department with injuries and infections they often need to have painful procedures performed that are essential to allowing them to recover.
- Conditions
- Emergency Department Procedural Sedation, Fracture Reduction, Abscess Incision and Drainage, Electrical Cardioversion
- Trial name
- NCT01211158
- Testing
- Ketofol, Propofol alone
- Where
- Canada
- Volunteers
- 284 people
- Sponsor
- Lions Gate Hospital
Anesthesia, Sedation
EEG Signal Correlates During Anesthesia and Sedation in Adults and Children
This prospective, multicenter, non-interventional observational study investigates the correlates between electroencephalographic (EEG) signals and pharmacological/clinical parameters during general anesthesia and procedural…
- Conditions
- Anesthesia, Sedation, Consciousness Monitors
- Trial name
- SPECTRALADUPED (NCT07460414)
- Where
- 2 sites in France
- Volunteers
- 330 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Midazolam
Pharmacokinetic Evaluation of MDZ028
Plasma concentration data were collected from 37 paedriatic patients and 12 healthy adults recruited in a single dose, open-label phase II pharmacokinetic study and in a single dose, randomised, open-label two-peiod crossover…
- Trial name
- MIDAZOLAM (NCT03639428)
- Testing
- Midazolam
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Conscious Sedation
Efficiency of Ventilation During Conscious Sedation in the Pediatric Intensive Care Unit
Pediatric patients admitted to the intensive care unit and requiring conscious sedation for minor surgical procedures are at risk to hypoventilate and retain CO2. The rise in CO2 levels is not well described and unpredicted.
- Trial name
- NCT01287572
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Failed Conscious Sedation During Procedure
The Efficacy and the Safety of Dexmedetomidine Sedation on the Pediatric Intensive Unit(PICU) Patients.
To observe the efficacy and safety of dexmedetomidine sedation on the patients admitted to the pediatric intensive care unit after surgery.
- Trial name
- NCT02296073
- Testing
- Midazolam, Dexmedetomidine, Fentanyl
- Volunteers
- 120 people
- Sponsor
- Anhui Provincial Children's Hospital
Dental Care for Children
Evaluation Ofe the Anxiolytic Effect of EMONO in Children During Dental Care (MOPEA)
The EquiMolar Oxygen and Nitrous Oxyde mix (EMONO) is listed by the ANSM (National Agency for the Safety of Medicines and Health Products) as drugs with enhanced surveillance.
- Trial name
- MOPEA (NCT03998774)
- Testing
- Evaluate the anxiolytic effect during dental care with MEOPA in children
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Nantes University Hospital
Conscious Sedation, Anxiety
Parental Presence During Fracture Reduction in Children at the Emergency Department; A Randomized Controlled Trial
Though much attention has been given to the practice of parental presence during invasive procedures in children in the ED, few studies have examined the patient's perspective.
- Trial name
- PP (NCT00809380)
- Testing
- Parental presence, Control
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- St. Justine's Hospital
Conscious Sedation
Adjunctive Atropine During Ketamine Sedation
Ketamine seems an obvious choice in the setting of an emergency department Ketamine leads to increased production of salivary and tracheal secretions Antisialagogues(atropine)therefore have been recommended as a routine adjunct…
- Trial name
- NCT00834470
- Testing
- Atropine
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital