Clinical trials: Consciousness, Level Depressed
Anxiety Disorders, Depression
Process and Outcomes in CBT for Anxious and Depressed Youth
The current study will evaluate the predictors, mediators, outcomes, and critical therapy processes associated with manual-based psychological therapies for 400 youth (ages 7-16 years) with anxiety and/or depression seeking…
- Trial name
- NCT03100279
- Testing
- Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Rutgers University
Major Depression
Discontinuation Study Of Citalopram (Antidepressant) in Depressed Adolescents
The purpose of the study is to evaluate whether it is advantageous for adolescents who have recovered from depression after a 6 to 12 week course of antidepressant treatment to stay on the treatment a further 6 months or is it…
- Trial name
- NCT00249886
- Testing
- Citalopram
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Depression
Effectiveness of Internet-Based Cognitive Behavioral Therapy for Treating Mothers With Depression
This study will evaluate the effectiveness of an Internet-based cognitive behavioral therapy program in treating mothers with depression who have young children.
- Trial name
- NCT00601393
- Testing
- Cognitive behavioral therapy (CBT), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Research Institute
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression
Adolescent Depression Associated With Parental Depression
Depression is difficult to identify, prevent and treat in adolescents because of complex and stigmatized multiform symptoms and pathways of care.
- Trial name
- AdoDesP (NCT03811041)
- Testing
- MDA, Routine Cares, Parental depression
- Where
- 12 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Brest
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Sleepiness, Daytime
Effects of Litebook EDGE™ Phototherapy on Academic Performance and Brain Activity
As children pass through puberty the timing of their sleep-wake cycle shifts and they experience a strong urge to stay up and awaken late.
- Trial name
- LiteBook (NCT05383690)
- Testing
- LED bright light treatment device
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Inflammatory Bowel Disease, Depression
Treatment of Depressed Adolescents With Physical Illness
The purpose of this study is a randomized trial of cognitive-behavioral intervention (CBI) for eligible adolescents who have Inflammatory Bowel Disease and subsyndromal depressive symptoms, but who did not meet diagnostic…
- Trial name
- NCT00446238
- Testing
- Cognitive Behavioral Therapy, Standard of Community Care Treatment
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Pittsburgh
Depression
Treatments for Improving Mood in Depressed Teens-3
Phase 3 is a randomized clinical trial of yoga vs group Cognitive Behavioral Therapy (CBT) for adolescents with depression.
- Trial name
- TeenThrive (NCT03831360)
- Testing
- Yoga, Group CBT
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brown University
Depressed
Sensitivity to Ovarian Hormones and Depression in Adolescents
The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression.
- Trial name
- SOHDA (NCT07317895)
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- University of Calgary
Hypoxic-Ischemic Encephalopathy, Birth Asphyxia
Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)
An extension of the MIDAB trial, the MIDAB-Follow-up trial will evaluate the neurodevelopmental outcomes at 22-26 months age of term/late preterm infants who were depressed at birth and received umbilical cord milking (UCM) or…
- Trial name
- MIDAB-FU (NCT03681314)
- Testing
- Umbilical Cord Milking
- Where
- 3 sites in India
- Sponsor
- Nemours Children's Clinic
Depression, Adolescent Behavior
Evaluation of an Asynchronous Remote Communities Approach to Behavioral Activation for Depressed Adolescents
The goal of this clinical trial is to learn if a digital health intervention, called "ActivaTeen," improves depression treatment for teenagers with depression.
- Trial name
- NCT06786247
- Testing
- ActivaTeen, Behavioral Activation
- Volunteers
- 70 people
- Sponsor
- University of Washington
Maternal Depression, Depression
Early Psychosocial Stimulation Program for Children of Depressed Mothers
Aim: To assess the feasibility of provision of an early psychosocial stimulation programme for the children of depressed mothers and to determine its effect on, mothers depression , mothers' knowledge and practices of…
- Trial name
- LTP (NCT00835016)
- Testing
- Early psychosocial stimulation (LTP)
- Where
- Pakistan
- Volunteers
- 260 people
- Sponsor
- Pakistan Institute of Living and Learning
Major Depressive Disorder
ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients
Background: despite developments a substantial part of patients with depression will only recover slowly. Light therapy from light boxes has shown antidepressant effects but have several limitations: time consuming, only allowing…
- Trial name
- NCT03821506
- Testing
- Dynamic Light, Usual care
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Major Depression, Anxiety Disorder
Tackling Depression and Anxiety: A Working Memory Intervention
Anxiety and depression are both associated with impairments in executive functions, including working memory (WM) which is needed to maintain and manipulate goal-relevant information.
- Trial name
- NCT02119923
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 240 people
- Sponsor
- Erasmus Medical Center
Depression
Behavioral Activation With Depressed Adolescents
Twenty percent of adolescents will have at least one episode of clinical depression by age 18, and 65% will experience transient or less severe depressive symptoms.
- Trial name
- NCT01137149
- Testing
- Behavioral Activation Therapy, Treatment as Usual- Psychotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Depressive Disorder, Sleep Disturbance
iACT & iTBS for Sleep Quality in Depressed Adolescents
This study evaluated whether combining an internet-delivered Acceptance and Commitment Therapy program with intermittent theta burst stimulation improves subjective sleep quality in adolescents with depressive disorders and sleep…
- Trial name
- NCT07807072
- Testing
- Internet-Delivered Acceptance and Commitment Therapy, Intermittent Theta Burst Stimulation
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Central China Normal University
Major Depressive Disorder
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood.
- Trial name
- NCT01804296
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Paul E. Croarkin
Depressed Lateral Condyle Fracture, Benign Bone Tumour Cavity
Bioactive Glass as Bone Graft Substitute in Operative Treatment of Bone - a 10 Years Follow-up Study
The main aim is to evaluate the long-term safety and bone healing in the operated area and to compare bioactive glass granules with autogenous bone as a filler material.
- Conditions
- Depressed Lateral Condyle Fracture, Benign Bone Tumour Cavity, Spinal Fusion
- Trial name
- NCT00935870
- Testing
- Bioactive glass and/or autogenous bone
- Where
- Finland
- Volunteers
- 63 people
- Sponsor
- Vivoxid Ltd
Depression
PRimary Prevention Of Depression in Offspring of Depressed Parents
The purpose of this randomised controlled trial is to see whether a group-based psychological intervention for families can reduce the inflated risk of depression in children and adolescents who have at least one parent who…
- Trial name
- PRODO (NCT02115880)
- Testing
- Prevention programme
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich