Clinical trials: Consciousness, Level Depressed
Major Depressive Disorder
Comparison of the Efficacy, Safety, and Relapse of ECT to ECT Plus Agomelatine for Depressed Patients
Our hypothesis is that using antidepressants during the ECT has a better efficacy and longer time to relapse/recurrence to the ECT without antidepressants.
- Trial name
- NCT04181567
- Testing
- electroconvulsive therapy, agomelatine
- Where
- Taiwan
- Volunteers
- 97 people
- Sponsor
- Kaohsiung Kai-Suan Psychiatric Hospital
Anodal Stimulation tDCS, Major Depression
Effects of tDCS on Cognitive Control and Emotion Regulation in Depressed Patients
Deficient cognitive control (CC) and the use of dysfunctional emotion regulation strategies (ERS) are both central characteristics of major depression.
- Conditions
- Anodal Stimulation tDCS, Major Depression, Cognitive Control, Emotion Regulation
- Trial name
- NCT03039387
- Testing
- anodal transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Major Depression
Effectiveness of Repetitive Transcranial Magnetic Stimulation in Depressed Patients
The purpose of this study is to evaluate clinical efficacy (affective and cognitive) in patients with moderate depression between TMS over the left Dorsolateral Prefrontal Cortex (DLPFC) with simulated TMS, as well as clinical…
- Trial name
- NCT02213016
- Testing
- Transcranial Magnetic Stimulation
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Nacional Autonoma de Mexico
Alcoholism, Depression
Sertraline and Cognitive Therapy in Depressed Alcoholics
This study will assess whether individuals treated with sertraline (Zoloft) and cognitive behavior therapy will experience improvement with their depression and consume less alcohol than individuals treated with a placebo and…
- Trial name
- NCT00000458
- Testing
- sertraline (Zoloft), cognitive behavior therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Depression, Suicidal Ideation
A Double-Blind Study of Buprenorphine Treatment of Acute Suicidality
The acutely suicidal patient presents a complex and dangerous clinical dilemma. Many suicidal patients receive antidepressant medications, but the onset of action of these medications is at least three weeks, and despite their…
- Conditions
- Depression, Suicidal Ideation, Suicidal Action
- Trial name
- NCT00863291
- Testing
- buprenorphine
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Abarbanel Mental Health Center
Depressive Disorder, Mood Disorder
Family Based Treatment of Depressed Adolescents
The purpose of this project is to assess the effectiveness of a family-based therapy (Attachment based family therapy-ABFT) for Norwegian adolescents (13-17 years) referred to specialist mental heath clinics.
- Conditions
- Depressive Disorder, Mood Disorder, Major Depression
- Trial name
- BudFam (NCT00700609)
- Testing
- Attachment Based Family therapy (ABFT)
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Helse Stavanger HF
Tobacco Smoking in Depressed Patients
Smoking Cessation And Reduction in Depression
It is well established in studies across several countries that tobacco smoking is more prevalent among depressed patients than the general population.
- Trial name
- scarid (NCT02124187)
- Testing
- Ecig 24 mg nicotine, Ecig 0 mg nicotine, Nicotine free inhalator
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Catania
Consciousness, Level Depressed, Intraoperative Awareness
Awareness During Blended Anaesthesia
the aim of this study was to estimate the relations between Bispectral Index values and explicit or implicit memory or dreams during two different minimal alveolar concentration (MAC) of sevoflurane in patients undergoing blended…
- Trial name
- NCT01800578
- Testing
- monitor for depth of hypnosis
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Germano De Cosmo
Depression
Evaluating Behavioral Activation Efficacy in Depressed Spanish-Speaking Latinos
Following a small, open-label pilot study that yielded very promising results of BATD, the current study will consist of a larger, randomized control trial (n=60) that will compare BATD to Supportive Counseling in outcomes of…
- Trial name
- NCT01958840
- Testing
- Behavioral Activation for Depression Treatment, Supportive Counseling
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Major Depressive Episode
Predictors of the Response and Relapse/Recurrence After ECT for Depressed Patients
Objective: Psychiatrists have long sought a quantifiable biomarker of electroconvulsive therapy (ECT) response. Although ECT is highly effective for treatment of patients with major depressive episode, a high rate of…
- Trial name
- NCT02032576
- Testing
- ECT for depressed patients
- Where
- Taiwan
- Volunteers
- 170 people
- Sponsor
- Kaohsiung Kai-Suan Psychiatric Hospital
Depression, Cognition Disorders
Therapy for Depressed Elders With Thought Problems
This study will compare the effectiveness of Problem Solving Therapy and Brief Supportive Therapy in treating elderly patients with major depression and thought problems.
- Trial name
- NCT00052091
- Testing
- Problem Solving Therapy, Brief Supportive Therapy
- Where
- 2 sites in United States
- Volunteers
- 221 people
- Sponsor
- University of Washington
Depressive Symptoms
Physical Exercise and Depressive Symptoms in Moderately or Severely Depressed Adults
This study is a comparative trial comparing the time course of depressive symptoms between moderately and severely depressed participants over a 10-week long exercise program
- Trial name
- EXIMOS (NCT05703776)
- Testing
- Nordic Walking
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Je Bouge Pour Mon Moral
Postnatal Depression
Tackling Postnatal Depression: Culturally Adapted Learning Through Play Plus (LTP+) Intervention for British Mothers of African and Caribbean Origin
By 2030, depression will be the leading global disease burden. Postnatal depression due to childbirth/parenting leads to long-term negative consequences for mothers, their children and their families.
- Trial name
- NCT05148260
- Testing
- Learning Through Play plus (LTP+), Psychoeducation
- Volunteers
- 80 people
- Sponsor
- Nottingham Trent University
Depressive Disorder
Depressed Mood Improvement Through Nicotine Dosing 2
Deficits in cognitive control are core features of late-life depression, contributing both to emotion dysregulation and problems with inhibiting irrelevant information, conflict detection, and working memory.
- Trial name
- DepMIND2 (NCT04433767)
- Testing
- Transdermal Nicotine patch
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Vanderbilt University Medical Center
Major Depressive Disorder, Cognitive Behavior Therapy
Using a Text-message System to Engage Depressed Adolescents in Cognitive-behavioral Therapy Homework
The primary goal of the pilot is to test the feasibility and utility of using a text-messaging system to engage adolescents in improved homework adherence during cognitive-behavioral therapy (CBT) for major depressive disorder.
- Conditions
- Major Depressive Disorder, Cognitive Behavior Therapy, Text Messaging
- Trial name
- NCT00919932
- Testing
- Paper and pen homework, Text message system homework.
- Volunteers
- 9 people
- Sponsor
- University of Pittsburgh
Depression
Group Interpersonal Psychotherapy for Depressed Adolescents in School-based Clinics
This study will assess the effectiveness of group interpersonal psychotherapy (IPT-AG) versus treatment as usual (TAU) in improving the treatment of depressed adolescents in school-based health clinics.
- Trial name
- NCT00270244
- Testing
- Group interpersonal psychotherapy for depressed adolescents (IPT-AG), Treatment as usual (TAU)
- Volunteers
- 16 people
- Sponsor
- New York State Psychiatric Institute
Major Depression, Bipolar Affective Disorder
Treatment Response In ECT Patients
Clarification Regarding Study Type: Observational This study is a prospective, non-interventional observational study. The decision to administer Electroconvulsive Therapy (ECT) and the selection of the anesthetic agent (ketamine…
- Conditions
- Major Depression, Bipolar Affective Disorder, Bipolar Depression Depressed Phase
- Trial name
- NCT07463911
- Testing
- Electroconvulsive Therapy (ECT)
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Nurdan Sağbaş
Depression
Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression
This study will evaluate the safety and effectiveness of methylphenidate in improving cognition and function in older adults with depression.
- Trial name
- NCT00602290
- Testing
- Citalopram, Methylphenidate (MPH)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of California, Los Angeles
Major Depressive Disorder (MDD)
Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People
Major depressive disorder was shown to be associated with pathological alterations within neurotransmitter systems of the brain.
- Trial name
- NCT06675851
- Testing
- WELLBUTRIN SR (Bupropion HCI) Sustained-Release Tablets, 150 mg; GlaxoSmithKline, Cipralex (escitalopram)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Depression
Comparing Delivery Methods of Cognitive Behavioral Therapy for Depressed African-American Dementia Caregivers
This study will compare the effectiveness of face-to-face cognitive behavioral therapy versus telephone-based cognitive behavioral therapy for treating African Americans who care for family members with dementia.
- Trial name
- NCT00769769
- Testing
- Psychotherapy
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Robert L. Glueckauf