Clinical trials: Consciousness, Level Depressed
Schizophrenia, Schizophreniform Disorder
Biomarkers in First Episode Schizophrenia
This study will identify and evaluate relevant biomarkers and structural brain imaging for understanding potential biological illness related mechanisms in medication-naïve subjects with early psychosis before and after…
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Depressed Type
- Trial name
- NCT02033382
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Down Syndrome, Polyendocrinopathies, Autoimmune
Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome
This study plans to learn more about Down syndrome. The investigators think there is a different level of the AIRE gene in individuals with Down syndrome.
- Conditions
- Down Syndrome, Polyendocrinopathies, Autoimmune, Respiratory Tract Infections, Autoimmunity
- Trial name
- NCT02421276
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depression
Neural Alteration Response to Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Depressed Patients
Electrical vagus nerve stimulation (VNS) was approved by FDA for treatment of chronic recurrent depression in 2005. Recently, non-invasive, transcutaneous auricular vagus nerve stimulation （taVNS） has already been used for…
- Trial name
- NCT03592446
- Testing
- Transcutaneous electrical vagus nerve stimulation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xidian University
Depression
Parent Psychoeducation and Cognitive Behavior Therapy for Latino Adolescents With Depression
This study will determine the effectiveness of adding a parent-involved intervention to cognitive behavior therapy in reducing depressive symptoms among Latino adolescents with depression.
- Trial name
- NCT00118469
- Testing
- Psychoeducation, Cognitive behavior therapy
- Where
- Puerto Rico
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression
PERsonalized Mood Augmentation Trial for Depressed Mood
The goal of this open-label single-arm study is to test personalized behavioral intervention for depressed mood.
- Trial name
- PERMA (NCT05662254)
- Testing
- Personalized Behavioral Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Zygomatic Arch Fracture
Ultrasound Guided Closed Reduction of Depressed Zygomatic Arch Fractures
Zygomatic arch fractures have always been treated with blind closed reduction and is the most commonly used method. Blind reduction of fractures might lead to inadequate reduction and associated complications of facial asymmetry…
- Trial name
- NCT04528264
- Testing
- Intraoperative ultrasound guided, Conventional blind reduction technique
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- College of Medical Sciences Teaching Hospital. Nepal
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Depression in Adolescence
Development of Online Mindfulness-Based Intervention for Thai-Depressed Adolescents
Project: "Development of Online Mindfulness-Based Intervention for Thai-Depressed Adolescents" For this project we adopted Kabat-Zinn's definition of mindfulness as the intentional and non-judgmental awareness of thoughts…
- Trial name
- NCT06595485
- Testing
- online mindfulness based intervention
- Where
- Thailand
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Mae Fah Luang University
Depression, Dual Diagnosis
Open-Label Creatine Study for Female Meth Users
Study Purposes and Objectives: The objectives should be stated in such a way that the reader can determine the appropriateness of the study design. If appropriate, state the specific hypotheses being tested and/or study aims.
- Conditions
- Depression, Dual Diagnosis, Substance Use
- Trial name
- NCT02189915
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw
Depressive Disorder, Anxiety Disorders
Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression
Psychological therapies for depression have demonstrated efficacy, but outcomes are still unsatisfactory, especially in cases with high comorbidity.
- Trial name
- NCT01829100
- Testing
- Group Behavioral Activation Therapy (GBAT)
- Where
- United States
- Volunteers
- 895 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Dermal Regeneration
Dermogenesis With Mesenchymal Stem Cells
Dermogenesis With Mesenchymal Stem Cells in treating Post Acne Depressed Spots
- Trial name
- MSCs (NCT06135519)
- Testing
- Autologous Mesenchymal stem cells injection, Homogenized fat injection
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Major Depressive Disorder
Non-invasive BCI and Application Verification for Depressed People
Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health.
- Conditions
- Depression, Major Depressive Disorder, Bipolar Depression
- Trial name
- NCT06417437
- Testing
- SSRI, rTMS, Neuro-Feedback
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Depression
A Neuroimaging Study of Open-label Placebo in Depressed Adolescents
Major depressive disorder (MDD) is the current leading cause of disability worldwide and adolescence is an especially vulnerable period for the onset of depression.
- Trial name
- OLP (NCT04201106)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression
A Trial of a Preventive Intervention Program for Chilean Families With Depressed Parents
The overall aim of this pilot study is to evaluate the acceptability and feasibility of an adaptation of Beardslee's 'Preventive Intervention Program (PIP) for Depression' in Chilean families.
- Trial name
- FamilyTalkCL (NCT02593266)
- Testing
- Preventive Intervention Program (PIP) for depression
- Where
- Chile
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chile
Healthy
Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study
The primary objective will be to study changes in putamen structural connectivity in healthy teens with meditation training. Hypothesis: Putamen structural node strength will increase in the training group compared to controls.
- Trial name
- NCT04254796
- Testing
- Training for Awareness, Resilience, and Action (TARA)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression
PRimary Prevention Of Depression in Offspring of Depressed Parents
The purpose of this randomised controlled trial is to see whether a group-based psychological intervention for families can reduce the inflated risk of depression in children and adolescents who have at least one parent who…
- Trial name
- PRODO (NCT02115880)
- Testing
- Prevention programme
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Sleepiness, Daytime
Effects of Litebook EDGE™ Phototherapy on Academic Performance and Brain Activity
As children pass through puberty the timing of their sleep-wake cycle shifts and they experience a strong urge to stay up and awaken late.
- Trial name
- LiteBook (NCT05383690)
- Testing
- LED bright light treatment device
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Suicide, Major Depressive Disorder
Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients
This study will try to provide a better understanding of the psychological, cognitive and electrophysiological factors that contribute to suicide in depressed patients.
- Conditions
- Suicide, Major Depressive Disorder, Quantitative EEG (qEEG)
- Trial name
- NCT04104698
- Testing
- Quantitative EEG
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Smoking, Depression
Smoking Cessation for Depressed Smokers
Objectives: Primary Aim: To conduct a preliminary randomized trial in smokers with current recurrent major depressive disorder (MDD), current MDD with a single episode of 2 years or more, and current dysthymia comparing combined…
- Trial name
- NCT00494728
- Testing
- Smoking Cessation Treatment, Nicotine Replacement Therapy, CBASP
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center