Clinical trials: Consciousness, Level Depressed
Depression, Major Depressive Disorder
Non-invasive BCI and Application Verification for Depressed People
Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health.
- Conditions
- Depression, Major Depressive Disorder, Bipolar Depression
- Trial name
- NCT06417437
- Testing
- SSRI, rTMS, Neuro-Feedback
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Neonatal Disorder, Asphyxia Neonatorum
Early or Late Cord Clamping in the Depressed Neonate
This study evaluates the hypothesis that delayed compared to early umbilical cord clamping will improve neonatal transition in terms of circulation and breathing during resuscitation.
- Trial name
- NepCordIII (NCT02727517)
- Testing
- Early (≤ 60 seconds) cord clamping, Delayed (≥ 180 seconds) cord clamping
- Where
- Nepal
- Volunteers
- 90 people
- Sponsor
- Uppsala University
Depression
Effects of Aerobic Exercise Intensity on Clinical & Neural Outcomes in Depressed Youth
This study will assess the effects of moderate vs. high intensity aerobic exercise, performed 3 times a week for 12 weeks under supervised conditions, on symptoms of depression, cognitive functioning and brain function in…
- Trial name
- NCT04110041
- Testing
- Aerobic Exercise
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Royal's Institute of Mental Health Research
Depression
A Neuroimaging Study of Open-label Placebo in Depressed Adolescents
Major depressive disorder (MDD) is the current leading cause of disability worldwide and adolescence is an especially vulnerable period for the onset of depression.
- Trial name
- OLP (NCT04201106)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Major Depression, Anxiety Disorder
Tackling Depression and Anxiety: A Working Memory Intervention
Anxiety and depression are both associated with impairments in executive functions, including working memory (WM) which is needed to maintain and manipulate goal-relevant information.
- Trial name
- NCT02119923
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 240 people
- Sponsor
- Erasmus Medical Center
Hypoxic-Ischemic Encephalopathy, Birth Asphyxia
Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)
An extension of the MIDAB trial, the MIDAB-Follow-up trial will evaluate the neurodevelopmental outcomes at 22-26 months age of term/late preterm infants who were depressed at birth and received umbilical cord milking (UCM) or…
- Trial name
- MIDAB-FU (NCT03681314)
- Testing
- Umbilical Cord Milking
- Where
- 3 sites in India
- Sponsor
- Nemours Children's Clinic
Insomnia, Depression
Development of an Insomnia Treatment for Depressed Adolescents
Major depressive disorder (MDD) occurs at least 11% of adolescents and approximately 53-90% of those adolescents have insomnia. If left untreated, insomnia increases the risk of relapse and recurrence of depressive episodes…
- Trial name
- NCT02163564
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Michigan
Depression, Depressive Disorder
Effects of Therapist Behavior on the Treatment of Depressed Adolescents
The purpose of this study is to identify and evaluate therapist behaviors that affect how well and how long adolescent patients stay in treatment for depression.
- Conditions
- Depression, Depressive Disorder, Dysthymic Disorder
- Trial name
- NCT00073359
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Denver
Depression
A Trial of a Preventive Intervention Program for Chilean Families With Depressed Parents
The overall aim of this pilot study is to evaluate the acceptability and feasibility of an adaptation of Beardslee's 'Preventive Intervention Program (PIP) for Depression' in Chilean families.
- Trial name
- FamilyTalkCL (NCT02593266)
- Testing
- Preventive Intervention Program (PIP) for depression
- Where
- Chile
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chile
Major Depression, Dysthymic Disorder
Interpersonal Psychotherapy for Depressed Adolescents and Parents
The purpose of this study is to examine the feasibility and acceptability of an adaptation of Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) that includes greater and more structured involvement of the parents in…
- Conditions
- Major Depression, Dysthymic Disorder, Adjustment Disorders, Depressive Disorder Not Otherwise Specified
- Trial name
- NCT00619411
- Testing
- Interpersonal Therapy for Depressed Adolescents & Parents
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Depression
Dyadic Interactions in Depressed and Non-Depressed Mothers and Their Infants
This study will examine 1) differences among mothers behaviors and how these behaviors influence their infants reactions, and 2) how mother-child interactions relate to children s temperament, and cognitive (thought processing)…
- Trial name
- NCT00044174
- Where
- United States
- Volunteers
- 701 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Healthy
Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study
The primary objective will be to study changes in putamen structural connectivity in healthy teens with meditation training. Hypothesis: Putamen structural node strength will increase in the training group compared to controls.
- Trial name
- NCT04254796
- Testing
- Training for Awareness, Resilience, and Action (TARA)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Major Depressive Disorder, Dysthymic Disorder
Cognitive Behavioral Therapy for Early-Onset Depression
Depression is a debilitating illness affecting large numbers of young people. In this study, children and adolescents ages 10 to 17 meeting criteria for clinical depression will participate in a 15-session group therapy…
- Trial name
- NCT00096642
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood.
- Trial name
- NCT01804296
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Paul E. Croarkin
Depression
PRimary Prevention Of Depression in Offspring of Depressed Parents
The purpose of this randomised controlled trial is to see whether a group-based psychological intervention for families can reduce the inflated risk of depression in children and adolescents who have at least one parent who…
- Trial name
- PRODO (NCT02115880)
- Testing
- Prevention programme
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Anxiety Disorders, Depression
Process and Outcomes in CBT for Anxious and Depressed Youth
The current study will evaluate the predictors, mediators, outcomes, and critical therapy processes associated with manual-based psychological therapies for 400 youth (ages 7-16 years) with anxiety and/or depression seeking…
- Trial name
- NCT03100279
- Testing
- Coping Cat/CAT Project, Primary and Secondary Coping Enhancement Therapy
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Rutgers University
Depression
Effect of Family-Based Prevention on Children of Depressed Parents
This study will test the Protecting Families Program, a 10-week prevention program for depressed parents and their pre-teenage children, by comparing the effectiveness of the program versus parent training alone.
- Trial name
- NCT00183365
- Testing
- Parent Skills Training, Protecting Families Program (PFP)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital of Philadelphia
Sleepiness, Daytime
Effects of Litebook EDGE™ Phototherapy on Academic Performance and Brain Activity
As children pass through puberty the timing of their sleep-wake cycle shifts and they experience a strong urge to stay up and awaken late.
- Trial name
- LiteBook (NCT05383690)
- Testing
- LED bright light treatment device
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Suicide, Major Depressive Disorder
Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients
This study will try to provide a better understanding of the psychological, cognitive and electrophysiological factors that contribute to suicide in depressed patients.
- Conditions
- Suicide, Major Depressive Disorder, Quantitative EEG (qEEG)
- Trial name
- NCT04104698
- Testing
- Quantitative EEG
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Depression in Adolescence
Increasing Treatment Response Rates in Depressed Adolescents Via Feedback-Informed IPDT
The overarching research project aims to evaluate of an internet-delivered affect-focused psychodynamic treatment (IPDT) for adolescents aged 15-19 with depression.
- Trial name
- ERiCA3 (NCT06193772)
- Testing
- Internet-delivered psychodynamic therapy (IPDT)
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Björn Philips