Clinical trials: Constipation - Functional
Constipation - Functional
Effect of a Mixture of Fibers and Carbohydrates on Intestinal Transit in Children Diagnosed With Functional Constipation
Once the patients who are candidates to enter the study are identified, the patients will be randomly be assigned to two groups, according to the sequence: Group A: study product+wash out+control product Group B: control…
- Trial name
- VEGY-DOWN(A) (NCT04028258)
- Where
- 3 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Laboratorios Ordesa
Functional Gastrointestinal Disorders, Gastroesophageal Reflux
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first…
- Conditions
- Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
- Trial name
- FUSID (NCT06031025)
- Testing
- Questionnaire, clinical examination
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Constipation
Effects of Probiotics (BioKid LR - Contains Nine Different Species of Probiotics Bacteria Including L. Reuteri) in Children With Functional Constipation
The goal of this clinical trial is to evaluate whether a probiotic supplement, BioKid LR®, can help maintain normal bowel movements after stopping laxative treatment (PEG 3350) in children aged 6 months to 17 years with…
- Trial name
- NCT06959758
- Testing
- Probiotic Arm
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Ferass Abu Hanna
Functional Constipation (FC), Chronic Idiopathic Constipation (CIC)
A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility.
- Trial name
- NCT05652205
- Testing
- Linaclotide
- Where
- 48 sites in United States, Bulgaria and 2 more
- Volunteers
- 123 people
- Sponsor
- AbbVie
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi
Functional Constipation
The Use of Lactobacillus Reuteri in Functional Constipation in Children
Functional constipation (FC) is a common condition in childhood, with an estimated prevalence of 0.7% to 29%.The diagnosis and treatment of FC can be difficult tasks, and children are often referred to specialist services causing…
- Trial name
- NCT03333070
- Testing
- probiotic - Lactobacillus reuteri
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Constipation - Functional
Evaluation of the Effectiveness of a Mobile Application in the Treatment of Children With Functional Constipation
This randomized, double-blind clinical trial evaluates the effectiveness of use of a mobile health application in supporting the treatment of functional constipation in children aged 4 to 18 years.
- Trial name
- NCT07025135
- Testing
- comparison between use of mobile app, Patient-caregiver dyad using printed recommendations
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Gdansk
Functional Constipation, Pelvic Floor Disorders
The Utility of Virtual Reality in the Management of Pediatric Functional Constipation With Pelvic Floor Dysfunction.
1. To determine if the adjunctive use of a Virtual Reality (VR) module on diaphragmatic breathing (DB) can improve the quality of life (QOL) and symptoms of children with functional constipation (FC) with pelvic floor dysfunction…
- Trial name
- NCT04172948
- Testing
- Oculus go headset/virtual reality headset, Diaphragmatic breathing
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
Irritable Bowel Syndrome With Constipation
A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation
The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of Irritable Bowel syndrome with Constipation (IBS-C), in children age 7-17 years.
- Trial name
- LIN-MD-63 (NCT02559817)
- Testing
- Linaclotide Dose A, Linaclotide Dose B, Linaclotide Dose C
- Where
- 48 sites in United States, Canada
- Volunteers
- 101 people
- Sponsor
- Forest Laboratories
Bladder-Bowel Dysfunction, Obesity & Overweight
Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel.
- Trial name
- OBE-BBD (NCT07724158)
- Testing
- Target physiotherapy, Exercise support intervention, Usual obesity care
- Where
- Portugal
- Volunteers
- 237 people
- Sponsor
- University of Lisbon
Constipation - Functional
Adherence/Outcomes After Use of Constipation Action Plan
Adherence to recommendations for treatment of chronic constipation in pediatric population is often poor. This study is attempting to improve adherence, and outcomes, by implementing a trial of a constipation action plan plus…
- Trial name
- NCT03821532
- Testing
- Constipation Action Plan
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Functional Constipation (FC)
This is a Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Efficacy and Safety of 2 Weight-based Treatment Groups of Plecanatide Versus Placebo in Children and Adolescent Participants 6 to Less Than 18 Years of Age With FC
The goal of this clinical trial is to learn if plecanatide can treat functional constipation in children and adolescents aged 6 to less than 18 years.
- Trial name
- Trulance (NCT07723924)
- Testing
- plecanatide
- Where
- 29 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bausch Health Americas, Inc.
Functional Constipation (FC)
Acupuncture for Children with Functional Constipation
Background of the study: Functional constipation (FC) is common in children and poses a significant burden to patients, their families and the healthcare system.
- Trial name
- ACU-PILOT (NCT06836362)
- Testing
- Acupuncture treatment
- Volunteers
- 18 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cerebral Palsy, Spastic
Role Of Physical Therapy In Relieving Constipation In Children With Spastic Cerebral Palsy
This study was conducted to determine the effectiveness of Physical Therapy management in relieving constipation among Spastic Cerebral Palsy children.
- Trial name
- NCT03379038
- Testing
- Progressive Physical Therapy, Maintenance Physical Therapy
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Isra University
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Infantile Colic, Gastroesophageal Reflux (GER)
BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months
Infants often experience functional gastrointestinal symptoms (e.g., colic, excessive gas, regurgitation, constipation, or loose stools) that distress families and may reflect an imbalance of the gut microbiome.
- Conditions
- Infantile Colic, Gastroesophageal Reflux (GER), Functional Constipation, Functional Diarrhea
- Trial name
- CTBE2503 (NCT07148583)
- Testing
- BioAmicus Complete, Usual Care (No Probiotic)
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Physical Therapy in Pediatric Functional Constipation
Physical Therapy for Functional Constipation in Children
Children diagnosed with functional constipation are subjected to physical therapy combined with conventional treatment
- Trial name
- NCT06207721
- Testing
- Polyethylene Glycols, Physical therapy program
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Delta University for Science and Technology
Functional Constipation
Co-supplementation With Bifidobacterium Longum W11 and Colopectin for Maintenance Therapy in Children With Functional Constipation
Functional constipation is a common condition in children and often requires prolonged maintenance treatment with macrogol. This randomized, double-blind, placebo-controlled trial will evaluate whether co-supplementation with…
- Trial name
- NCT07536698
- Testing
- Bifidobacterium longum W11 (Bowell®) + Colopectin (Colopectin®)
- Volunteers
- 100 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Pelvic Floor Dysfunction, Defecation Disorders
The Relationship Between Pelvic Floor Dysfunction and Quality of Life, Functional Capacity, Gait Parameters, and Static Balance in Children With Defecation Disorders
Defecation disorders are common in children and may adversely affect pelvic floor function, gait, balance, functional capacity, and health-related quality of life.
- Trial name
- NCT07727837
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Functional Constipation
A Trial of Three Types of Enemas Used to Treat Functional Constipation in Children
Functional constipation is extremely common in children and is defined as painful, hard stools or firm stools for twice or less per week.
- Trial name
- NCT01823848
- Testing
- Sodium phosphate enema, Normal saline enema, Mineral oil enema
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles