Clinical trials: Contraction
Uterine Atony, Uterine Tone Disorders
Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections
Insufficient uterine tone resulting in atony can potentiate hemorrhage and adverse outcomes for the parturient. Oxytocin is the first pharmacologic agent used, followed by methylergonovine, carboprost, and misoprostol.
- Conditions
- Uterine Atony, Uterine Tone Disorders, Postpartum Hemorrhage
- Trial name
- NCT03303235
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic
Functional Benefits of Multisite Surgery for the Upper Limb of Children With Cerebral Palsy
The aim of the study is to investigate the impact of individualized multisite neuro-orthopedic surgery of the upper limb in children with Cerebral Palsy on unilateral functional capacities and bimanual performance.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic, Infantile Hemiplegic Cerebral Palsy
- Trial name
- NCT04395729
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Muscle Strength, Sport Injury
Relationship Between the Functional Movement Screen and Isokinetic Muscle Strength of Knee in Different Sport Branches
This study was conducted to demonstrate the correlation between the functional movement screen and the isokinetic muscle strength with objective data.
- Conditions
- Muscle Strength, Sport Injury, Muscle Contraction
- Trial name
- NCT05964556
- Testing
- Functional Movement Screen (FMS), Isokinetic Muscle Evulation of Knee Muscles
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Sarcopenia
Sarcopenia and Aging
Objective: Evaluate the muscular strength in the ageing process and identify the changes between the abdominal muscles, upper and louver edges.
- Trial name
- NCT00907010
- Volunteers
- 48 people
- Sponsor
- Universidade de Franca
Pre Term Labor, Multiple Pregnancy
Study to Support Fetal Heart Rate and Uterine Contraction for Preterm Labor in Singleton and Multiple Pregnancies
The purpose of this study is to compare the Monica AN24 fetal monitor to previously FDA approved devices for Fetal Heart Rate and Uterine Contractions in labor for Multiples and pre term labor.
- Trial name
- NCT01360905
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Monica Healthcare Ltd
Pregnancy; Habitual Aborter, Weeks of Gestation 37 or More
Accuracy and Reliability of Fetal Heart Rate and Uterine Contraction Monitoring Method
Clinical Investigation Protocol for a study designed to determine the equivalence of the Monica AN24 monitor to Philips 50XM for fetal heart rate (FHR) and uterine contraction (UC) monitoring during labor.
- Trial name
- NCT01280357
- Testing
- Monica AN24 (K101081), Philips 50XM
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monica Healthcare Ltd
Heart Block, Heart Block Complete
Effect of Site of Right Ventricular (RV) Pacing on RV Function, Left Ventricular (LV) Dyssynchrony and Contraction Efficiency
To evaluate RV systolic function and LV mechanical dyssynchrony and function in different lead position in the RV during permanent pacemaker implantation by using speckle tracking echocardiography (STE) and 3D volumetric ejection…
- Conditions
- Heart Block, Heart Block Complete, Systolic Function
- Trial name
- NCT06636851
- Testing
- Pacemaker and defibrillator
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- South Valley University
Implants, Breast
Sonication of Explanted Breast Implants for Detection of Subclinical Infection
Objective. Capsular contracture is a frequent complication after breast implantation with unclear etiology. Summary Background Data: Microorganisms may trigger chronic periimplant inflammation with subsequent capsular fibrosis.
- Trial name
- NCT01138891
- Volunteers
- 121 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postpartum Hemorrhage
In-vitro Myometrial Contractility After Oxytocin Pre-exposure in Women With Advanced Maternal Age and Morbid Obesity
Women with advanced maternal age and morbid obesity, have a higher incidence of labor induction/ augmentation and cesarean section (CS), and are at a greater risk for postpartum hemorrhage (PPH).
- Trial name
- NCT01865669
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Sedentary Lifestyle
Effectiveness of Adding Voluntary Pelvic Floor Muscle Contraction to a Pilates Exercises Program
Adding voluntary pelvic floor muscle contraction to a Pilates exercises program can improve the pelvic floor muscle strength on sedentary nulliparous women.
- Trial name
- NCT02748473
- Testing
- Pilates Exercises program, Pelvic floor muscle strength, 3D perineal ultrasound
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Athletic Performance, Soccer
Unilateral vs Bilateral Isometric Training in Youth Soccer Players
This randomized controlled trial investigates the effects of unilateral and bilateral isometric strength training integrated into an 8-week complex training program on neuromuscular performance in elite youth soccer players.
- Conditions
- Athletic Performance, Soccer, Resistance Training
- Trial name
- NCT07556315
- Testing
- Unilateral Isometric Training, Bilateral Isometric Training, Complex Strength Training
- Where
- Poland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Pregnancy - Labor Monitoring
Multi-Reader Multi-Case Study to Identify Uterine Contractions Recorded From Laboring Patients by Practicing Clinicians
This multi-reader multi-case study was designed to evaluate the performance of SureCALL® EMG Labor Monitor® (SureCALL®)to the predicate Tocodynamometer device (TOCO) using the performance of an Intrauterine Pressure Catheter…
- Trial name
- NCT01282723
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Reproductive Research Technologies, LP
Preterm Labor
Oral Progestogen Supplementation in the Prevention of Recurrent Uterine Contraction in Preterm Labor
The purpose of this study is to evaluate the effect of oral progesterone supplementation in preterm labor on the prevention of recurrent uterine contraction and prolonging pregnancy period, and its side effect.
- Trial name
- NCT02262481
- Testing
- dydrogesterone
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Spastic Cerebral Palsy
Effect of Post Isometric Relaxation Technique & Eccentric Muscle Contraction on Hamstring Spasticity in CP
Cerebral Palsy is a disorder of movement and posture due to deficit or lesion of immature brain. Out of all types of cerebral palsy 77.4% is spastic cerebral palsy.
- Trial name
- NCT03708757
- Testing
- Post isometric relaxation - Group I, Eccentric Muscle contraction - Group II
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Lung Diseases, Sleep Apnea Syndromes
Regulation of Pharyngeal Muscle Contraction - SCOR in Cardiopulmonary Disorders of Sleep
To determine the degree to which neuro-psychological performance and general health status and function may be impaired in subjects with mild and moderate degrees of sleep-related respiratory disturbances (SRRD), as compared to…
- Trial name
- NCT00005320
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Disorders
Resynchronization of Left Ventricular Contraction After Reimplantation of Anomalous Left Coronary Artery
Spontaneous resynchronization of dyskinetic segments of the left ventricle occurs after coronary bypass surgery in adults and has been shown in some children.
- Trial name
- NCT00268112
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Children's Healthcare of Atlanta
Dehydration, Weight Loss
Effect of Dehydration on Sleep Quality, Cognitive Skills, and Electromyographic Responses in Combat Athletes
This study examines the effects of rapid dehydration-induced weight loss on combat athletes' sleep quality, cognitive skills, and isokinetic strength performance.
- Conditions
- Dehydration, Weight Loss, Weight Cycling, Sleep
- Trial name
- NCT07118904
- Testing
- Rapid weight loss through dehydration
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy, Muscle Contraction
The Muscle in Children With Cerebral Palsy - Longitudinal Exploration of Microscopic Muscle Structure.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contraction, Muscle Spasticity
- Trial name
- CPBiopsyBTX (NCT05497609)
- Testing
- no intervention. Care as ususal
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Eva Ponten
Ventricular Arrhythmia, Ventricular Tachycardia
IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry
This is a prospective multi-center international registry. The objective of this registry is to collect prospective data on patients undergoing catheter ablation for Ventricular Tachycardia (VT) and Premature Ventricular…
- Conditions
- Ventricular Arrhythmia, Ventricular Tachycardia, Premature Ventricular Contraction (PVC), Cardiomyopathy
- Trial name
- IVTCC (NCT04520347)
- Where
- 41 sites in United States, Canada and 5 more
- Volunteers
- 10,000 people
- Sponsor
- University of California, Los Angeles
Postpartum Hemorrhage
Investigating the Effect of Extracellular Calcium on Oxytocin-induced Human Myometrial Contractility In-vitro
Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide and is caused most commonly by poor uterine muscle tone after delivery.
- Trial name
- NCT02274454
- Testing
- Oxytocin, Calcium
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital