Clinical trials: Contrast Agent
Advanced Cancer
Bevacizumab and Temsirolimus in Patients With Advanced Malignancy
The goal of this clinical research study is to find the highest tolerable dose of Avastin (bevacizumab) and Torisel (temsirolimus) that can be given, in combination, to patients with advanced cancer that has spread or is unable…
- Trial name
- NCT00610493
- Testing
- Bevacizumab, Temsirolimus, Additional Blood Drawn
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- M.D. Anderson Cancer Center
Brain Diseases
Multi-center Study of Artificial Intelligence Model for Gadolinium-based Contrast Agent Reduction in Brain MRI (MAGNET)
MAGNET is a multi-center and prospective study to minimize Gadolinium-based Contrast Agent (GBCA) combining novel artificial intelligence (AI) methods with pre-contrast images and/or low-dose images to synthesize virtual…
- Trial name
- MAGNET (NCT05754476)
- Testing
- Low-dose GBCA levels
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Contrast-associated Acute Kidney Injury
Contrast-enhanced Computed Tomography and Acute Kidney Injury
Rationale and objectives: Since 1930 it has been accepted that intravenous injection of io-dinated contrast agent as part of contrast-enhanced computed tomography (CE-CT) imaging can induce a contrast-associated acute kidney…
- Trial name
- NCT07091656
- Testing
- there is no intervention
- Where
- France
- Volunteers
- 1,463 people
- Sponsor
- Beaujon Hospital
Abdominal Injury
Contrast Ultrasound for Pediatric Trauma - Comparative Evaluation (CAPTURE Study)
This multicenter study aims to evaluate the accuracy of contrast-enhanced ultrasound (CEUS) in diagnosing abdominal solid organ injuries in pediatric patients.
- Trial name
- NCT04718441
- Testing
- Lumason
- Where
- 5 sites in United States
- Volunteers
- 68 people
- Sponsor
- David Mooney
Hypothyroidism
Pediatric Risk of Hypothyroidism With Iodinated Contrast Media
This is a Phase 4 multicenter prospective study to estimate the proportion of patients aged birth to 3 years who develop hypothyroidism within 6 months after receiving intravascular iohexol (Omnipaque™), iodixanol (Visipaque™)…
- Trial name
- NCT03631771
- Testing
- Iohexol, Iodixanol, Iopromide
- Sponsor
- GE Healthcare
Primary CNS Lymphoma (PCNSL)
Treatment of Primary CNS Lymphoma ( FTD )
The purpose of this study is to evaluate the efficacy and safety of FTD regiment (fotemustine, temozolomide and dexamethasone ) for patients with primary CNS lymphoma.
- Trial name
- NCT05274139
- Testing
- HD-MTX-Ara-C regimen, FTD regimen
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Mingzhi Zhang
Contrast Induced Nephropathy
Hydration and Contrast-Induced Nephropathy in Primary Angioplasty
The purpose of this study is to determine whether hydration with sodium bicarbonate is more effective than hydration with sodium chloride to prevent contrast induced nephropathy in patients undergoing Primary Coronary…
- Trial name
- NCT00770614
- Testing
- sodium bicarbonate solution, Isotonic saline
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- Ospedale Misericordia e Dolce
Neuroendocrine Tumors, Carcinoid Tumors
Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumors
This protocol is designed to test the efficacy of 68Ga-DOTATOC PET/CT in diagnosis, staging, and measurement of response to treatment in patients with somatostatin receptor positive tumors.
- Conditions
- Neuroendocrine Tumors, Carcinoid Tumors, Neuroblastoma, Medulloblastoma
- Trial name
- GA-68 (NCT01619865)
- Testing
- 68Ga-DOTATOC PET/CT
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- Sue O'Dorisio
Crohn's Disease in Pediatric Patient
Usefulness of Contrast-enhanced Ultrasound (CEUS) in Crohn's Disease Pediatric Patients
Purpose: There is no previous contrast enhanced ultrasound (CEUS) study for pediatric Crohn disease patients. There are adult studies which included adolescent patients.
- Trial name
- NCT04660136
- Testing
- contrast enhanced ultrasound
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Kawasaki Disease, Heart Disease
Real Time Myocardial Contrast Echocardiography and Dobutamine Stress Perfusion Magnetic Resonance Imaging
The present study is designed to: 1. investigate the safety and efficacy of Real time myocardial echocardiography (RT-MCE) in adolescents and adults ages 12-50 with congenital and acquired congenital heart disease 2.
- Trial name
- ECHOBIKE (NCT00861848)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention II
As a multi-center, retrospective observation study in southern China, this study included the main study population of patients who underwent coronary angiography at 5 hospitals from Guangzhou, Shenzhen, Yangjiang, Maoming and…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT05050877
- Where
- China
- Volunteers
- 184,855 people
- Sponsor
- Guangdong Provincial People's Hospital
Breast Cancer
Quantitative Dynamic Contrast Enhanced Breast MRI
The purpose of this study is to see if dynamic contrast enhanced (DCE) MRI imaging makes it possible to distinguish benign conditions of the breast from malignant tumors and provide better information than can be obtained with…
- Trial name
- NCT00582764
- Testing
- perform dynamic contrast enhanced (DCE) MRI
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Contrast Enhanced Ultrasound, Ultrasonic Diagnosis
International Delphi Study to Develop Standardized Quality Criteria and a Rating Tool for Liver CEUS Image Quality Assessment
This study aims to establish international consensus-based quality criteria for contrast-enhanced ultrasound (CEUS) examinations of the liver and to develop a standardized tool for assessing CEUS image and examination quality.
- Conditions
- Contrast Enhanced Ultrasound, Ultrasonic Diagnosis, Liver
- Trial name
- ICON LiverCEUS (NCT07656181)
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Contrast Induced Nephropathy
Assessment of the Effect of Atorvastatin on Prevention of CIN in Patients Undergoing Coronary Angiography
As the effect of statin use before the angiography to prevent contrast induced nephropathy (CIN) is not well-known, the aim of the current study is to assess the effect of atorvastatin on prevention of CIN in patients undergoing…
- Trial name
- CIN (NCT02113540)
- Testing
- Atorvastatin
- Where
- Iran
- Sponsor
- Isfahan University of Medical Sciences
Cerebrospinal Fluid
Assessment of Cerebrospinal Fluid Flow Related Disorders Using a Phase-contrast Magnetic Resonance Imaging Technique.
Cerebrospinal fluid is a clear, colorless fluid that circulates in the cranial and spinal subarachnoid spaces, located between the pia and arachnoid matters.
- Trial name
- NCT03656016
- Testing
- Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diagnostic Self Evaluation, Central Nervous System Diseases
Safety and Efficacy Evaluation of DOTAREM® in MRI of Central Nervous System (CNS) Lesions
The purpose of this study is to look at the safety (what are the side effects)and efficacy (how well does it work) of Dotarem® when used in taking images of the brain / spine.
- Trial name
- SENTIO (NCT01211873)
- Testing
- Dotarem (gadoterate meglumine), Magnevist (gadopentetate dimeglumine)
- Where
- 52 sites in United States, Argentina and 9 more
- Volunteers
- 416 people
- Sponsor
- Guerbet
Endovascular Abdominal Aortic Aneurysm Repair
Contrast Ultrasound in the Surveillance of Endovascular Abdominal Aortic Aneurysm Repair
The purpose of this study is to support the suspected expectation that Contrast enhanced Ultrasound (CUS) detects all endoleaks that have been detected by Computed Tomography (CT), and also find a number of leaks missed by CT.
- Trial name
- NCT01022892
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Magnetic Resonance Imaging
Contrast-enhanced MRI in Children 2 Months to <2 Years
The purpose of this study is to determine pharmacokinetics, safety and efficacy of Magnevist in children 2 months to < 2 years of age
- Trial name
- NCT00937391
- Testing
- Gadopentetate dimeglumine (Magnevist, BAY86-6661)
- Where
- 13 sites in United States, Germany
- Volunteers
- 54 people
- Sponsor
- Bayer
Stroke, Acute
Contrast Induced Acute Kidney in Patients With Acute Stroke
Computed tomographic angiography (CTA) is recommended for identifying eligible patient with acute ischemic stroke (AIS) to receieve endovascular treatment.
- Trial name
- NCT03132558
- Testing
- Radiopaque Media
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Renal Cell Carcinoma
Efficacy of Ultrasound Contrast Agent to Assess Renal Masses
Patients with an incidentally discovered small renal masses (SRM) < 4 cm in diameter are included. All patients will undergo biopsy for tissue diagnosis. Most patients will be followed by imaging.
- Trial name
- NCT01062178
- Testing
- Definity
- Where
- Canada
- Volunteers
- 167 people
- Sponsor
- University Health Network, Toronto