Clinical trials: Control Patients
Critical Illness
Topical Application of Silver Nanoparticles and Oral Pathogens in Ill Patients
The purpose of this study is to determine whether oral topic silver nanoparticles are effective to reduce potential pathogen microbial loads in mechanical ventilation patients.
- Trial name
- NCT02761525
- Testing
- silver nanoparticles
- Volunteers
- 50 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Type 1 Diabetes Mellitus
A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes
The objective of DIAGNODE-3 is to evaluate the efficacy and safety of three intranodal injections of 4 μg of Diamyd also known as retogatein compared to placebo, along with oral Vitamin D supplementation, to preserve endogenous…
- Trial name
- DIAGNODE-3 (NCT05018585)
- Testing
- Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®, Colecalciferol 2000 IU
- Where
- 60 sites in United States, Czechia and 7 more
- Volunteers
- 321 people
- Sponsor
- Diamyd Medical AB
Family Witnessed Resuscitation, Empathy Education
VIDEO LEARNING FOR EMPATHY, ETHICS AND FAMILY WITNESSED RESUSCITATION
This clinical trial (randomized controlled experimental study) aims to learn about the effects of presenting the family-witnessed CPR process from a patient's perspective through 360° virtual reality and 2D video within…
- Conditions
- Family Witnessed Resuscitation, Empathy Education, Ethics Nursing, Education Nursing
- Trial name
- NCT07692568
- Testing
- 360 Degree Virtual Reality Video, 2D Standard Video
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Acute Graft-versus-host Disease
Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies
To observe the effect of stem cell infusion on the development of acute graft-versus-host disease (aGVHD) in patients with malignant hematologic diseases after allogeneic peripheral blood hematopoietic stem cell transplantation…
- Trial name
- NCT06294678
- Testing
- Time of stem cell infusion
- Where
- 6 sites in China
- Volunteers
- 198 people
- Sponsor
- Anhui Provincial Hospital
Acne Vulgaris
Effectiveness of Zinc Supplementation With Topical Retinoids in Acne Vulgaris Patients
The study was 8 weeks, randomized, double-blind, placebo-controlled trial to assess the effect of zinc sulphate on symptoms of mild and moderate acne vulgaris in 122 patients. Participants was assessed at baseline, and 8 weeks.
- Trial name
- NCT04899843
- Testing
- Zinc sulphate tablet 20 mg
- Where
- Bangladesh
- Volunteers
- 122 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Diabete Mellitus
Impact of Therapeutic Education for Type 2 Diabetic Patients During Ramadan.
This randomized controlled trial evaluates the impact of therapeutic education, with or without personalized coaching, on clinical and biological outcomes in patients with type 2 diabetes during Ramadan fasting.
- Trial name
- NCT07112625
- Testing
- education and coaching, education
- Where
- Tunisia
- Volunteers
- 85 people
- Sponsor
- University of Monastir
Hereditary Periodic Fevers
Study of Efficacy and Safety of Canakinumab in Patients With Hereditary Periodic Fevers
This study is to determine whether canakinumab is able to induce and maintain a clinically meaningful reduction of disease activity in participants with Hereditary Periodic Fevers (HPF) compared to placebo.
- Trial name
- NCT02059291
- Testing
- Canakinumab
- Where
- 65 sites in United States, Belgium and 14 more
- Volunteers
- 203 people
- Sponsor
- Novartis Pharmaceuticals
Moderate to Severe Atopic Dermatitis
Dilute Bleach Baths in Pediatric Patients With Atopic Dermatitis
The purpose of this study is to determine if twice weekly 10 minute dilute bleach baths decreases disease severity in patients with moderate to severe atopic dermatitis.
- Trial name
- NCT01286220
- Testing
- Dilute bleach baths, Water
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Efficacy of Ciclesonide Versus Placebo Administered Either as Once Daily or Twice Daily in Patients Treated Previously With an Inhaled Corticosteroid
To investigate the efficacy of ciclesonide MDI either as once daily or a twice daily regimen in patients with mild to moderate asthma, who have previously been treated with an inhaled corticosteroid.
- Trial name
- NCT00174733
- Testing
- Ciclesonide (XRP1526)
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Sanofi
Anorexia Nervosa
Treating the Fear of Gaining Weight in Anorexia Nervosa
The main aim of this study is to develop a virtual reality (VR) embodiment-based exposure technique to improve the treatment of anorexia nervosa (AN).
- Trial name
- NCT04028635
- Testing
- Cognitive-behavioral therapy plus VR-based body exposure, Cognitive behavioral therapy
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- University of Barcelona
Respiratory Failure
Cycling of Sedative Infusions in Critically Ill Pediatric Patients
The purpose of this study is to determine if the reduction of the total amount of sedative critically pediatric ill patients receive in the PICU will achieve a significant decrease in mechanical ventilation days and a decrease in…
- Trial name
- NCT01333059
- Testing
- Midazolam, Normal saline, Fentanyl
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Javier Gelvez, MD
Feasibility, Acceptability of Health Care
Introduction of Preconception Care Through Public Health System for Improving MNCH&FP
The goal of this study is to test the feasibility and acceptability of introducing preconception care into the public health system targeting newlywed couples in increasing the uptake of maternal, neonatal health, and family…
- Trial name
- MNCH&FP (NCT06175520)
- Testing
- Preconception care (PCC)
- Where
- Bangladesh
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Type1diabetes
4T Sustainability Program
The goal of the 4T program is to implement proven methods and emerging diabetes technology into clinical practice to sustain tight glucose control from the onset of type 1 diabetes (T1D) and optimize patient-reported and…
- Trial name
- NCT06314048
- Testing
- CGM and RPM
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Stanford University
Immunologic Diseases, Autoimmune Diseases
Safety and Efficacy Study of LJP 394 (Abetimus Sodium) to Treat Lupus Kidney Disease
The purpose of this study is to determine whether LJP 394 (abetimus sodium) is safe and effective in delaying and reducing renal flares in patients with lupus nephritis.
- Conditions
- Immunologic Diseases, Autoimmune Diseases, Systemic Lupus Erythematosus, Lupus Nephritis
- Trial name
- NCT00035308
- Testing
- Abetimus sodium (LJP 394)
- Where
- 82 sites in United States, Austria and 8 more
- Volunteers
- 330 people
- Sponsor
- La Jolla Pharmaceutical Company
Spinal Muscular Atrophy, Neuromuscular Disorders
Study of Feasibility to Reliably Measure Functional Abilities' Changes in Nonambulant Neuromuscular Patients Without Trial Site Visiting
Clinical trials organization in several neuromuscular disorders (NMD) has some specific issues. Nonambulant status and difficulties with transportation are among them.
- Trial name
- NCT02235090
- Testing
- Direct current stimulation of cervical spinal cord
- Where
- Ukraine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charitable Foundation Children with Spinal Muscular Atrophy
Respiratory Distress Syndrome, Newborn, Infant, Premature
Neural Control of Non-invasive Ventilation in the Preterm
The present study will use a new type of respirator in premature babies who need help with their breathing. This new respirator uses signals from the baby's diaphragm - the most important breathing muscle - to control the timing…
- Trial name
- NCT00368485
- Testing
- Neurally Controlled Mechanical Ventilation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Asthma
Trial of Vitamin D Supplementation in Asthma
The study null hypothesis is that vitamin D supplementation will not influence time to upper respiratory tract infection or time to severe asthma exacerbation in adult and adolescent patients with asthma.
- Trial name
- ViDiAs (NCT00978315)
- Testing
- Cholecalciferol, Miglyol oil
- Where
- 4 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- Barts & The London NHS Trust
Radiotherapy; Adverse Effect, Radiotherapy; Complications
Analysis of Outcomes and Adverse Events of Patients Undergoing Radiation Therapy
Analysis of outcomes and adverse events of patients undergoing radiation therapy. Quality control using data base of patient records 2000-2025
- Conditions
- Radiotherapy; Adverse Effect, Radiotherapy; Complications, Quality of Life
- Trial name
- NCT05192876
- Testing
- Radiotherapy
- Where
- Switzerland
- Volunteers
- 25,000 people
- Sponsor
- Daniel Zwahlen
Cystic Fibrosis
The Effect of rhDNase on Ventilation Inhomogeneity in Patients With Cystic Fibrosis
This study will assess whether rhDNase treatment improves ventilation inhomogeneity as assessed by lung clearance index (LCI) in patients with cystic fibrosis (CF).
- Trial name
- NCT00557089
- Testing
- rhDNAse
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- The Hospital for Sick Children
Cystic Fibrosis
Safety, Tolerability and Pharmacokinetics of BIIL 284 BS in Adult and Pediatric Cystic Fibrosis (CF) Patients
Safety, tolerability and pharmacokinetics following repeated doses (15-day dosing)
- Trial name
- NCT02269189
- Testing
- BIIL 284 BS, high dose, BIIL 284 BS, low dose
- Volunteers
- 36 people
- Sponsor
- Boehringer Ingelheim