Clinical trials: Corneal Opacity
Corneal Opacities
Corneal Opacities in Children
A prospective observational study on corneal opacities in infants and children (1 month to 18 years old) will be conducted at CHLA. Most of these cases will be due to congenital corneal opacity (e.g.
- Trial name
- OCT (NCT02117323)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Oregon Health and Science University
Keratoconus, Corneal Opacity
OCT in Diagnosis of Irregular Corneas
This main goal of this study is to improve the detection, classification, monitoring, and treatment of irregular corneas due to keratoconus, warpage, dry eye, scar, stromal dystrophies, and other corneal conditions.
- Conditions
- Keratoconus, Corneal Opacity, Corneal Dystrophy
- Trial name
- NCT03504800
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Mucolipidosis Type IV
The Natural History of Mucolipidosis Type IV
The purpose of this study is to define the natural history of Mucolipidosis Type IV and identify potential clinical outcome measures.
- Trial name
- NCT01067742
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Baylor Research Institute
Corneal Opacity
OCT-guided LALAK in Children
The primary goal of the trial is to determine if laser-assisted lamellar anterior keratoplasty (LALAK) will reduce the risks of post-operative complications such as adhesions, glaucoma and cataract that are associated with…
- Trial name
- LALAK (NCT01579643)
- Testing
- OCT guided laser-assisted lamellar anterior keratoplasty (LALAK), Penetrating Keratoplasty (KP)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Oregon Health and Science University
Lipoprotein Lipase Deficiency, Inborn Error of Lipid Metabolism
Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Homozygous familial Hypercholesterolemia from blood
- Conditions
- Lipoprotein Lipase Deficiency, Inborn Error of Lipid Metabolism, Corneal Arcus
- Trial name
- BioHoFH (NCT03198897)
- Where
- 4 sites in Germany, India and 1 more
- Sponsor
- CENTOGENE GmbH Rostock
Keratoconus, Corneal Dystrophies
Laser Assisted Procedures in Penetrating Keratoplasty
Laser- assisted procedures in penetrating keratoplasty (PK) are proposed to improve the surgical outcomes: minimally invasive procedures, improved biomechanical stability of the transplanted flap, reduction of rejection risks…
- Conditions
- Keratoconus, Corneal Dystrophies, Corneal Opacity
- Trial name
- NCT02173847
- Testing
- Penetrating keratoplasty, Femtosecond laser, Diode laser
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Ospedale Santo Stefano
Graft Rejection
Pathogenetic Risk Factors for Corneal Graft Rejection
There are many predictors that may influence the development of corneal graft rejection after penetrating keratoplasty. In our study investigators analysed the results of keratoplasty and the risk factors for graft rejection.
- Trial name
- NCT06281587
- Testing
- penetrating keratoplasty
- Where
- Russia
- Volunteers
- 93 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Corneal Diseases
Dynamic Light Scattering and Keratoscopy for Corneal Examination
This pilot study will examine the usefulness of a new instrument called the Dynamic Light Scattering (DLS) device for documenting and monitoring changes in the cornea, the front part of the eye where contact lenses are placed.
- Trial name
- NCT00050466
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Corneal Opacity
Characteristics of Trachomatous Corneal Opacity in Fayoum University Hospital
The purpose of this study is to assess the characteristics of trachomatous corneal opacity in patients with signs of trachoma using Anterior segment Optic coherence tomography and Pentacam
- Trial name
- Trachoma (NCT06000150)
- Testing
- Corneal topography
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Omar Said