Clinical trials: Coronary
Cardiovascular Diseases, Heart Diseases
Epidemiology of Body Mass Index Rebound
To investigate the relationship between obesity, body mass index (BMI) rebound, body composition changes, associated factors (e.g., diet, physical activity), and cardiovascular risk factor status in a longitudinal study of young…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00006307
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Patent Ductus Arteriosus
Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates
To compare the effectiveness of rectal vs. intravenous paracetamol in the medical treatment of significant PDA in neonates.
- Trial name
- NCT06256211
- Testing
- Paracetamol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soha mahmoud Hussien mahdy
Heart Rate Determination, Patient Participation
Promoting Children's Participation in Conventional X-ray Examinations
The goal of this explorative observational study is to map the procedure and child centered approach in the examination for children that undergo conventional X-ray examinations.
- Trial name
- NCT06322264
- Testing
- Measurement of variation in heart rate
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Lund University
Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction
Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery.
This study examines the effects of coughing exercises and incentive spirometry (IS) on lung function and recovery in children who undergo heart surgery.
- Conditions
- Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery
- Trial name
- CEXIS (NCT07405333)
- Testing
- Coughing Exercises, Incentive Spirometry, Standard Postoperative Care
- Where
- 4 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Bipolar Disorder, Subsyndromal Depressive Phase
Heart Rate Variability of Patients With Bipolar Disorder in Subsyndromal Depressive Phase
The purposes of this study were: (1) to compare heart rate variability between bipolar patients in subsyndromal depressive phase and healthy controls (2) to evaluate the relation between the severity of subsyndromal depressive…
- Conditions
- Bipolar Disorder, Subsyndromal Depressive Phase, Heart Rate Variability
- Trial name
- NCT01455038
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Congenital Heart Disease in Children, Cardiac Surgical Procedures
Predictive Pre and Peroperative Factors for MODS-2 in Pediatric Cardiac Surgery
Pediatric cardiac surgery has a relatively high morbi-mortality. Despite great advances in surgical techniques, today the mortality rate is about 3% and morbidity is about 30-40%.
- Conditions
- Congenital Heart Disease in Children, Cardiac Surgical Procedures, Outcome Assessment, Organ Dysfunction Scores
- Trial name
- FPMODS2 (NCT05284500)
- Testing
- Pediatric cardiac surgery with cardiopulmonary bypass
- Where
- Belgium
- Volunteers
- 152 people
- Sponsor
- Brugmann University Hospital
Marfan Syndrome
The Oxford Marfan Trial
The primary objective of the trial is to estimate the effects of allocation to irbesartan, or doxycycline, or a combination of both irbesartan and doxycycline, compared with placebo, on measures of elastic function of the aorta…
- Trial name
- NCT01949233
- Testing
- Irbesartan 150-300mg capsules daily for 6 months, Doxycycline 100-200mg capsules daily for 6 months
- Where
- 2 sites in United Kingdom
- Volunteers
- 56 people
- Sponsor
- University of Oxford
Cardiovascular Disease
High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
The aim of this study is to compare the effect of high dose and low dose of Atorvastatin in reduction level of C-reactive protein (CRP) in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi…
- Trial name
- NCT01306565
- Testing
- Low dose Atorvastatin, High dose atorvastatin
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Hormozgan University of Medical Sciences
Fontan Procedure
Clinical Outcomes in Fenestrated Extra-Cardiac Fontan in Low Preoperative Risk Profiles
Evaluation of fenestration benefit in Extra-cardiac total cavo-pulmonary connection (Fontan procedure) in single ventricle anomaly, comparing clinical outcomes of patients with low preoperative risk profiles in prospective study
- Trial name
- NCT03503032
- Testing
- Extracardiac Fontan, Fontan fenestration
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Coronary Artery Perforation
Covered Stents in Treatment of Coronary Artery Perforation
Covered stents have been mainly used for treatment of potentially life-threatening coronary artery perforation and coronary artery aneurysm.
- Trial name
- CRACK (NCT04630314)
- Testing
- Percutaneus Coronary Intervention
- Where
- 6 sites in Poland
- Volunteers
- 119 people
- Sponsor
- Medical University of Silesia
Primary Ciliary Dyskinesia, Kartagener Syndrome
Genetics of Primary Ciliary Dyskinesia
This study is designed to study DNA sequencings for mutations in a research genetic test panel of genes (which contains all 32 known and/or published genes associated with PCD).
- Trial name
- NCT02389049
- Where
- 8 sites in United States, Canada
- Volunteers
- 320 people
- Sponsor
- University of North Carolina, Chapel Hill
Out-Of-Hospital Cardiac Arrest
The Systematic Approach for Identification of Cause Among Out-of-hospital Cardiac Arrest Survivors
The cause of cardiac arrest mostly determines outcomes of cardiac arrest survivors. Identifying and treating the cause of cardiac arrest constitute a critical part in post-arrest care.
- Trial name
- NCT06012838
- Testing
- Cause classification of OHCA protocol
- Where
- Taiwan
- Volunteers
- 16 people
- Sponsor
- National Taiwan University Hospital
Myocardial Infarction
Sevoflurane and Percutaneous Coronary Intervention by Stent
Increase in CK-MB after percutaneous coronary angioplasty more than 100% of baseline can represents a problem to the patients resulting in increase of morbidity and mortality.
- Trial name
- NCT02671084
- Testing
- sevoflurane
- Where
- Brazil
- Volunteers
- 701 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Constipation
Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease
Comparison of Circular(Soave)and Heart-shaped Anastomosis in Hirschsprung's disease.
- Trial name
- NCT02234219
- Testing
- Heart-shape anastomosis, Soave anastomosis
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Tongji Hospital
Congenital Heart Disease, Telerehabilitation
The Effect of Telerehabilitation Exercises in Children With Congenital Heart Disease
This study aims to investigate the effects of functional inspiratory muscle training on physical performance and quality of life in pediatric patients with congenital heart disease.
- Conditions
- Congenital Heart Disease, Telerehabilitation, Functional Inspiratory Muscle Training
- Trial name
- CHD (NCT07854171)
- Testing
- Inspiratory Muscle Training, Functional Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Izmir Democracy University
Acute Coronary Syndrome, Recurrent Myocardial Infarction
Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients
This study aims to evaluate the effect of statin for primary prevention, towards lowering the incidence of recurrent myocardial infarction, cardiogenic shock and mortality in ACS patients.
- Conditions
- Acute Coronary Syndrome, Recurrent Myocardial Infarction, Cardiogenic Shock
- Trial name
- NCT03596944
- Testing
- Statin
- Where
- Indonesia
- Volunteers
- 145 people
- Sponsor
- Tarumanagara University
Supraventricular Tachycardia
Management of Supraventricular Tachycardia of Children
Supraventricular tachycardia (SVT) is defined as an abnormally rapid heart rhythm originating above the ventricles. It usually has narrow complex tachycardia but this is not always the case.
- Trial name
- NCT03528616
- Testing
- adenosine,Propranolol,flecainide, amiodarone, propranolol, digoxin and procainamide.
- Volunteers
- 50 people
- Sponsor
- Assiut University
Complex Congenital Heart Defect, Dysfunctional RVOT Conduit
COMPASSION S3 Post-Approval Study
This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve…
- Conditions
- Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
- Trial name
- NCT04860765
- Testing
- SAPIEN 3 THV
- Where
- 19 sites in United States
- Volunteers
- 150 people
- Sponsor
- Edwards Lifesciences
Chronic Total Occlusion of Coronary Artery
Early and Midterm Outcomes of Intravascular Ultrasound (IVUS) Versus Non-IVUS Guidance in Complex Coronary Chronic Total Occlusion (CTO) Revascularization.
Various CTO percutaneous coronary intervention (PCI) studies defined CTO as as a substantial atherosclerotic blockage with >3 months duration of TIMI (Thrombolysis in Myocardial Infarction) 0 flow other than via collaterals.
- Trial name
- NCT04917432
- Testing
- intravascular ultrasound (IVUS), Conventional CTO PCI (non-IVUS guided)
- Volunteers
- 70 people
- Sponsor
- Assiut University
Patent Foramen Ovale, PFO
Lifetech Cera™ PFO Occluder Post-Market Clinical Follow-Up
The objective of this post-market registry is to assess the clinical use of the Lifetech Cera™ PFO Occluder in a real-world and on-label fashion.
- Trial name
- NCT05893758
- Testing
- The Cera™ PFO Occluder
- Where
- 5 sites in Poland
- Volunteers
- 94 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
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