Clinical trials: Coronary Interventions
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
STEMI
Erectile Dysfunction After Percutaneous Coronary Intervention Versus the Thrombolytic Therapy in Acute ST Elevation Myocardial Infarction
Erectile dysfunction is a common sexual problem affecting up to one-third of men throughout their life. It is now well recognized that risk factors for erectile dysfunction (ED) include the same risk factors as coronary artery…
- Trial name
- NCT03328156
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiovascular Disease
NUYou:mHealth Intervention to Preserve and Promote Ideal Cardiovascular Health
The purpose of the study is to investigate the preservation or promotion of health in students during the college years.
- Trial name
- NUYou (NCT02496728)
- Testing
- Mobile Health Application, Environmental Cues, Social Support
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Coronary Artery Disease
Clinical and Procedural Outcomes of Ostial Left Anterior Descending Artery Intervention With or Without Crossover to Left-main
Prospective interventional study evaluating clinical and procedural outcomes of patients with ostial left anterior descending artery lesion PCI alone or crossover with left main artery
- Trial name
- NCT05933473
- Testing
- Percutaneous coronary intervention
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Dual Anti-platelet Therapy
Aspirin-Free Strategy After 3-6 Month Dual Antiplatelet Therapy in Acute Coronary Syndrome
This randomized controlled trial aims to evaluate the safety and efficacy of an aspirin-free strategy after 3-6 months of dual antiplatelet therapy (DAPT) in patients with acute coronary syndrome (ACS) who have undergone complete…
- Trial name
- NCT07736196
- Testing
- Aspirin-Free Strategy, Dual Antiplatelet Therapy
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obesity
Test of an Intervention to Increase Physical Activity Among School Children
The specific aims of this study are to: 1) evaluate the impact of a novel intervention delivered via school-based physical education (PE) on adolescents who have a high sensitivity to exercise-induced negative affect; 2)…
- Trial name
- NCT01876602
- Testing
- feeling states exercise intervention
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
ST Elevation Myocardial Infarction
Effect of Upstream Treatment With High Intensity Statin on the Outcomes of STMI Patients Treated With PPCI
Effect of upstream treatment with high intensity statin on the outcome of ST segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention
- Trial name
- NCT04754789
- Testing
- Atorvastatin, Aspirin
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preeclampsia Postpartum, Adverse Pregnancy Outcomes
A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
United States maternal mortality and preterm birth rates are among the highest among high-income countries due in part to a combination of racial, regional and socioeconomic disparities in access to care and overall health.
- Trial name
- AW2H (NCT06353256)
- Testing
- usual postpartum care, usual postpartum care + community health worker intervention
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Rheumatic Heart Disease
Effectiveness of Edutainment-Based Interventions in Increasing Knowledge of Rheumatic Fever and Rheumatic Heart Disease Among School-Going Children in Nepal: Study Protocol for Colors to Save Hearts Quasi-Experimental Pretest-Posttest Study
Background: Acute rheumatic fever (ARF) and its sequela, rheumatic heart disease (RHD), remain significant public health concerns in low- and middle-income countries, including Nepal.
- Trial name
- NCT07065474
- Testing
- education material
- Where
- Nepal
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Kathmandu Institute of Child Health
Coronary Artery Disease
Decision Support Tool for Revascularisation Options in Coronary Artery Disease
Together with patients and healthcare professionals, we want to design a Decision Support Tool (DST) that will help people with coronary artery disease to understand and choose treatments that best reflect their preferences and…
- Trial name
- DECIDE-CAD (NCT06567626)
- Testing
- Decision Support Tool (DECIDE-CAD)
- Where
- 2 sites in United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Heart Disease
Digital Cardiovascular Health Promotion Among School-going Adolescents in Nepal
The goal of this HRIDAYA project is to see if a digital mobile game can improve knowledge about heart disease among school-going adolescents. The researchers will divide adolescents of public and private schools into two groups.
- Trial name
- HRIDAYA (NCT06668675)
- Testing
- A serious game known as the 'Happy Heart' will be used as the intervention.
- Where
- Nepal
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Kathmandu Medical College and Teaching Hospital
Unexpected Hospital Mortality, Death, Sudden, Cardiac
Prevention of Serious Adverse Events in Acute Care Hospitals by Afferent Limb and Response Method Intervention - the ALARM Intervention Study.
1. Summary Growing evidence suggests that a significant proportion of in-hospital patient deaths occur after serious adverse events (SAE's).
- Conditions
- Unexpected Hospital Mortality, Death, Sudden, Cardiac, Unplanned Intensive Care Unit Admission
- Trial name
- ALARM (NCT01949025)
- Testing
- ALARM intervention
- Where
- Belgium
- Volunteers
- 69,656 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Aortic Stenosis, Hypoplastic Left Heart Syndrome
Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome
For fetuses with severe aortic stenosis, in utero balloon aortic valvuloplasty may improve fetal growth of left heart structures and thus improve potential for biventricular repair strategies after birth.
- Trial name
- NCT01736956
- Testing
- Fetal Aortic Valvuloplasty
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder, Mental Disorders
Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric…
- Trial name
- NCT04606966
- Testing
- Therapeutic Horseback Riding, Barn Activity, Hybrid
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Adult
LasaiON is an Evidence-informed, Multimodal Self-regulation Program Designed to Reduce Emotional Distress and Strengthen Stress-regulation Skills by Combining Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Breathing Supported by Heart-rate Variability Biofeedback (HRV-B; emWave).
The goal of this clinical trial is to evaluate whether the LasaiON program, which combines transcutaneous auricular vagus nerve stimulation (taVNS) with breathing supported by heart rate variability biofeedback (HRV-B; emWave)…
- Trial name
- LasaiON (NCT07498881)
- Testing
- LasaiON
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Neurodegenerative Diseases, Osteoarthritis
Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions
To evaluate for any adverse effects that may be related to the administration and reception of autologous adipose derived stromal vascular fraction (SVF).
- Conditions
- Neurodegenerative Diseases, Osteoarthritis, Erectile Dysfunction, Autoimmune Diseases
- Trial name
- NCT01953523
- Testing
- Administration of autologous adipose derived SVF
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Elliot Lander
Congenital Heart Disease, Cardiac Catheterization
CHAIN_brazilian Registry of Congenital HeArt Disease INtervention and Angiography
Design: Observational - Cross study with followed up for 30 days. The Primary Objective is to realize a record that reflects a national overview of the role of cardiac catheterization in patients with congenital heart disease in…
- Conditions
- Congenital Heart Disease, Cardiac Catheterization, Brazilian Electronic Registration, Catheterization Diagnostic or Therapeutic
- Trial name
- CHAIN (NCT02074527)
- Where
- Brazil
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hospital do Coracao
Heart Diseases
Heart-health Promotion
The researchers intend to use the Expanded Health Belief Model in enhancing heart-health preventive behaviors among high school female students
- Trial name
- NCT05949892
- Testing
- Expanded Health Belief Model-Based Intervention
- Where
- Iraq
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Fetal Anesthesia
Pharmacokinetic and Pharmacodynamic Investigations of Fetal Anesthesia During Maternal Fetal Surgery
This study examines how three medications commonly used during fetal surgery, fentanyl, rocuronium, and atropine, behave in the fetus.
- Trial name
- NCT07571811
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Train Your Brain and Exercise Your Heart? Advancing the Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder (ADHD) is a developmental disorder that has a severe impact on a child's life and society. The core symptoms are attention problems, hyperactivity and impulsivity.
- Trial name
- NCT01363544
- Testing
- Neurofeedback, Exercise, methylphenidate
- Where
- 6 sites in Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- R. van Mourik