Clinical trials: Critical Care
Pain Management, Music Therapy
MUSIDORE PED Study
The aim of this study is to measure the efficacy of music during a painful procedure in pediatric intensive care unit. Music therapy has real effects on the pain level already proven in adults units.
- Trial name
- MUSIDORE (NCT03916835)
- Testing
- Pain evaluation ( FLACC scale) before and during the cleaning care with and without music therapy.
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Pediatric Disorder, Critical Illness
Attitudes to Decisions to Withdraw or Withhold Life-sustaining Treatments in Critically Ill Children
The aim of this study is to investigate attitudes on decisions to withdraw or withhold life-sustaining treatments in critically ill children in Swedish intensive care units.
- Conditions
- Pediatric Disorder, Critical Illness, Ethics, Narrative
- Trial name
- LSTPedSurvey (NCT06281743)
- Testing
- Survey
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Pediatric Critical Illness; Physical Function Assessment; Functional Status; Rehabilitation
Validity of the Children's Chelsea Critical Care Physical Assessment Tool (cCPAx-TR) in Turkish Pediatric Intensive Care Patients
This single-center, prospective observational study aims to translate, culturally adapt, and evaluate the validity and reliability of the Children's Chelsea Critical Care Physical Assessment Tool (cCPAx) in Turkish pediatric…
- Trial name
- NCT07241455
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medeniyet University
Airway Morbidity, Airway Disease
Video Laryngoscopy in Pre-hospital Critical Care
Difficult conditions and critically ill and injured patients may complicate endotracheal intubation in the pre-hospital setting.
- Conditions
- Airway Morbidity, Airway Disease, Respiratory Insufficiency, Respiratory Failure
- Trial name
- NCT02035449
- Testing
- McGrath MAC
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Patient Safety, Organizational Change
Generalizing TESTPILOT to New Single Family Room NICUs
Complex service interventions are neither smooth nor easy in any transitioning healthcare facility. Simulations performed in the new environment reinforce patient safety by uncovering safety threats, enabling their correction…
- Trial name
- TESTPILOT (NCT02574104)
- Testing
- Simulate a functional NICU prior to moving patients
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Critical Illness, Intensive Care Unit Syndrome
Post ICU Follow up: A Questionnaire Survey of Aftercare in Denmark
This study aims to investigate current aftercare activities in Denmark after intensive care unit (ICU) treatment. The hypothesis is that a large number of hospitals offer aftercare, and these interventions are heterogenic and…
- Trial name
- NCT02784574
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Zealand University Hospital
Acute Respiratory Failure, Respiratory Insufficiency
HERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport
The HERMES Phase III study is an international, multicenter, prospective observational investigation designed to characterize the quality and safety of patient transport during advanced respiratory support.
- Conditions
- Acute Respiratory Failure, Respiratory Insufficiency, Respiratory Distress, Critical Illness
- Trial name
- HERMES (NCT07805603)
- Testing
- Advanced Respiratory Support During Patient Transport
- Where
- 4 sites in Colombia, Egypt and 2 more
- Volunteers
- 565 people
- Sponsor
- Medipol University
Central Line-associated Bloodstream Infection (CLABSI)
Implementation Program to Improve CHG Bathing Compliance
This study will be a multicenter, cluster randomized, step-wedged design. The unit of randomization will be the inpatient units admitted critically ill patients, with the interventions being carried out over 4 months.
- Trial name
- NCT03898115
- Testing
- CHG Education
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Feng Shui
Feng Shui And Emotional Response in the Critical Care Environment Study
Objective: To assess whether the feng shui of critical care bed spaces affects the inner harmony of nursing staff Design: Prospective cohort study Setting: Doncaster critical care department Participants: Critical care nursing…
- Trial name
- FARCE (NCT03265587)
- Testing
- No intervention
- Volunteers
- 408 people
- Sponsor
- Doncaster And Bassetlaw Hospitals NHS Foundation Trust
Weaning From Mechanical Ventilation in Care Unit
Prediction of the Spontaneous Breathing Test Success Using Biosignal and Biomarker in Critical Care Unit by a Machine Learning Approach
Context: Several authors have been interested in applying Artificial Intelligence (AI) to medicine, using various Machine Learning (ML) techniques: managing septic shock, predicting renal failure...
- Trial name
- NCT05886803
- Testing
- Spontaneous ventilation test
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Critical Illness, Child, Only
Epidemiological Study of the Microbiota in Critically Ill Children
Objectives: To study the composition of the microbiota in critically ill children, and to know the relationship of its microbiota with clinical complications and inflammation biomarkers.
- Conditions
- Critical Illness, Child, Only, Intensive Care Unit
- Trial name
- BIOUCIP (NCT04435470)
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad de Granada
Rehabilitation
Early Rehabilitation in Critical Illness Survivors
Background: Few studies showed that early rehabilitation on the Intensive Care Unit (ICU) results in a better functional outcome at hospital discharge and reduced hospital stay.
- Trial name
- ER (NCT02754505)
- Testing
- Early rehabilitation, Usual care
- Where
- Austria
- Volunteers
- 53 people
- Sponsor
- Danube Hospital
Telemedicine, Critical Care
Evaluation of the Impact of Telemedicine in Pediatric Intensive Care Units
This study will be a cluster randomized controlled trial to assess the impact of telemedicine in Pediatric Intensive Care Units (PICU), through daily tele-rounds with a board certified physician and educational activities, in…
- Conditions
- Telemedicine, Critical Care, Pediatric, Adolescent
- Trial name
- NCT05260710
- Testing
- Telemedicine Intervention
- Volunteers
- 1,760 people
- Sponsor
- Hospital Moinhos de Vento
Coronavirus
Viral Infection and Respiratory Illness Universal Study[VIRUS]: COVID-19 Registry
Researchers are creating a real time COVID-19 registry of current ICU/hospital care patterns to allow evaluations of safety and observational effectiveness of COVID-19 practices and to determine the variations in practice across…
- Trial name
- COVID-19 (NCT04323787)
- Testing
- observational
- Where
- 4 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Mayo Clinic
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Delirium
Efficacy of Quetiapine for Pediatric Delirium
This study is designed to assess the safety and efficacy of quetiapine as treatment for pediatric delirium.
- Trial name
- NCT02056171
- Testing
- quetiapine
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Weill Medical College of Cornell University
Airway Management, Emergency
Prehospital Emergency Airway Research.
The creation of an airway registry will allow an improvement in the quality of care, the safety of critically ill patients in pre-hospital situations, and a reduction in morbidity and mortality related to airway management.
- Trial name
- PhEAR (NCT07289139)
- Where
- Spain
- Volunteers
- 4,300 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Lung Cancer
A Study to Evaluate Guideline Adoption Through Quality Improvement Project (QIP) in Pulmonary and Critical Care Medicine (PCCM) Department
This is a cluster randomized controlled trial with PCCM department in each site being the cluster. Fifty-four sites' PCCM departments will be randomized to the QIP arm versus control arm in 2:1 allocation ratio.
- Trial name
- LC PCCM QIP (NCT06484972)
- Volunteers
- 1,728 people
- Sponsor
- China-Japan Friendship Hospital
Critical Illness, Burnout, Professional
Effect of Around the Clock Intensivist Coverage on Intensive Care Unit (ICU) Outcomes
Intensive Care Units (ICU) are an important, but troubled, part of modern health care systems. While it seems likely that both the technical and structural elements of ICU care are important determinants of relevant ICU outcomes…
- Conditions
- Critical Illness, Burnout, Professional, Education, Medical, Patient Satisfaction
- Trial name
- NCT01146691
- Testing
- Alternative Intensivist staffing models
- Where
- 2 sites in Canada
- Volunteers
- 627 people
- Sponsor
- University of Manitoba
Critical Illness, Infection, Mixed
Biomarkers of Acute Serious Illness in Children
This study is a large multi-centre collaboration between a busy regional paediatric intensive care transport service (Children's Acute Transport Service, CATS), four large paediatric intensive care units (PICUs at Great Ormond…
- Conditions
- Critical Illness, Infection, Mixed, Children, Only
- Trial name
- BASIC (NCT03238040)
- Testing
- None, observational study
- Where
- 4 sites in United Kingdom
- Volunteers
- 674 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust