Clinical trials: DVT
Venous Thrombosis, Deep, Arthroplasty Complications
Selective Thromboembolism Prophylaxis After Arthroplasty
Asian populations have a lower rate of high-risk gene mutations of venous thrombosis, which means a reasonable perioperative anticoagulant management after hip or knee arthroplasty for Caucasian populations may be too excessive…
- Trial name
- NCT03804697
- Testing
- selective anticoagulation
- Volunteers
- 197 people
- Sponsor
- Guangdong Provincial People's Hospital
Postthrombotic Syndrome
Prevalence of Post-Thrombotic Syndrome in Deep-Vein Thrombosis (DVT) Patients Treated With Dabigatran
The primary objective in this cross-sectional study is to assess the prevalence of post-thrombotic syndrome (PTS) in the two treatment arms of the RE-COVER studies (warfarin versus dabigatran).
- Trial name
- DABI-PTS (NCT03050138)
- Where
- 3 sites in Canada, Norway and 1 more
- Volunteers
- 351 people
- Sponsor
- Oslo University Hospital
Central Venous Catheter Thrombosis, Central Venous Catheter Associated Bloodstream Infection
t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection
The purpose of this pilot study is to test feasibility of concept, consent and enrollment rates, and mechanics of study designed to assess if intra-catheter dwells of tissue plasminogen activator (t-PA) is effective in decreasing…
- Trial name
- TOPCAT (NCT03672006)
- Testing
- alteplase (recombinant t-PA), Heparin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Deep Vein Thrombosis
Limited Compression Ultrasound by Emergency Physicians to Exclude Deep Vein Thrombosis
Deep vein thrombosis is a common condition seen in the Emergency Department. Standard of care for diagnosis of DVT includes a combination of a clinical pre-test probability rule known as Well's criteria, D-dimer blood testing…
- Trial name
- NCT01007045
- Where
- 2 sites in Canada
- Volunteers
- 227 people
- Sponsor
- Queen's University
On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis
This Research Proposal Focuses on Evaluating the Effectiveness of a Nursing Care Protocol in Preventing Deep Vein Thrombosis (DVT) in Patients Undergoing On-pump Cardiac Surgery. The Study Will Include an Intervention Group That Receives the Nursing Protocol and a Control Group That Receives Routine
The primary focus of this research proposal is to examine the efficacy of a nursing care protocol in preventing the occurrence of deep vein thrombosis (DVT) in patients undergoing on-pump cardiac surgery.
- Conditions
- On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis, DVT Prophylaxis, DVT Prevention
- Trial name
- DVT (NCT07347652)
- Testing
- IPC devices facilitate venous return by simulating the physiological effects of muscle contraction, reducing venous stasis.
- Where
- Cyprus
- Volunteers
- 67 people
- Sponsor
- Near East University, Turkey
Deep Vein Thrombosis, Pulmonary Embolism
Exercise Intolerance and Skeletal Muscle Bioenergetics in Children With Deep Venous Thrombosis
This is a prospective cohort study of 30 patients who are 8-21 years of age with venous thromboembolism (VTE)- either lower extremity deep venous thrombosis (DVT) or pulmonary embolism (PE).
- Trial name
- NCT04294849
- Testing
- Magnetic Resonance Imaging, Bicycle Ergometry, Lab Panel
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Texas Southwestern Medical Center
Traumatic Intracranial Haemorrhage
OPtimal Timing of Thromboprophylaxis in Traumatic IntraCranial Haemorrhage - Pilot Study
Victims of trauma with severe head injury who have bled into their brains are at high risk of developing blood clots in their legs.
- Trial name
- OPTTICH (NCT02260908)
- Testing
- Enoxaparin
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- McMaster University
Venous Thromboembolism
Special Drug Use Investigation of Xarelto for Venous Thromboembolism (VTE)
The objective of this investigation is to assess safety and effectiveness of Xarelto under practice routine use in VTE secondary prevention after acute DVT, focusing on hemorrhagic-related AEs, recurrent venous thromboembolism…
- Trial name
- JPMS-XAR-VTE (NCT02558465)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Japan
- Volunteers
- 2,540 people
- Sponsor
- Bayer
Post-Op Complication
A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery
The purpose and objectives of this study is to investigate whether reducing the existing arm restrictions on patients who receive Cardiac Implantable Electronic Devices (CIED) will result in an improved patient experience post…
- Trial name
- LENIENT (NCT04915261)
- Testing
- Lenient Arm Restriction, Strict Arm Restriction
- Where
- Canada
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Deep Vein Thrombosis, Venous Thromboembolism
Phase 1 Pediatric Pharmacokinetics/Pharmacodynamics (PK/PD) Study
This is the first evaluation of edoxaban in pediatric subjects. In this Phase 1 study, a single dose of edoxaban will be given to pediatric subjects who require anticoagulant therapy to see what the body does to the drug…
- Trial name
- NCT02303431
- Testing
- Edoxaban low dose, Edoxaban high dose
- Where
- 35 sites in United States, Canada and 7 more
- Volunteers
- 66 people
- Sponsor
- Daiichi Sankyo
Acute Limb Ischemia, Arterial Occlusion Mesenteric Artery Superior
Post Market Surveillance to Evaluate the Efficacy and Safety of the INDIGO Aspiration System in Japan
This study aims to confirm the safety and effectiveness of the INDIGO Aspiration System in patients requiring immediate treatment for acute lower extremity artery occlusion, acute superior mesenteric artery occlusion, or severe…
- Conditions
- Acute Limb Ischemia, Arterial Occlusion Mesenteric Artery Superior, Acute DVT of Lower Extremity
- Trial name
- JapanIndigoPMS (NCT06446024)
- Testing
- Mechanical aspiration thrombectomy
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Penumbra Inc.
Venous Thromboembolism, Delivery of Health Care
Improving Venous Thromboembolism Prophylaxis
Preventing the formation of blood clots in the veins so they do not injure leg veins or travel to the lungs, also called venous thromboembolism prophylaxis (VTE-P) is an essential component of safe in-patient care, yet it is…
- Conditions
- Venous Thromboembolism, Delivery of Health Care, Quality Improvement
- Trial name
- NCT01304108
- Testing
- VTE-P Tollgate, BLAZE Pop up, Usual Care
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Deep Vein Thrombosis
D-dimer and Pre-test Clinical Probability Score in Cancer Patients With Suspected Deep Vein Thrombosis of the Legs
Patients with cancer have a high risk of deep vein thrombosis which often develops in the veins of the lower limbs. The initial evaluation of clinically suspected deep vein thrombosis includes the estimation of the clinical…
- Trial name
- NCT02341937
- Testing
- Diagnostic tests for suspected deep vein thrombosis
- Where
- Italy
- Volunteers
- 239 people
- Sponsor
- G. d'Annunzio University
Pharmacomechanical Thrombolysis, Deep Vein Thrombosis
The Study of Percutaneous Mechanical Thrombectomy Treating Acute Deep Vein Thrombosis of Lower Extremities
This study is a prospective, multicenter, real world, observational study intended to understand tmechanical thrombectomy in the treatment of acute deep venous thrombosis of lower extremities, It is estimated that 600 patients…
- Trial name
- NCT05356767
- Testing
- Pharmacomechanical thrombolysis
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Post Thrombotic Syndrome, Deep Vein Thrombosis
Physical Activity in Children at Risk of Post-thrombotic Sequelae (PACT)
'The PACT trial' is randomized pilot trial to demonstrate the feasibility and potential effectiveness of a personal "fitness tracker" to improve adherence to an activity regimen following an initial acute DVT in children.
- Trial name
- PACT (NCT03075761)
- Testing
- Fitbit, 30-minute education session
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Texas Southwestern Medical Center
Pediatric Venous Thromboembolism
Rivaroxaban in Pediatric Patients With DVT
Prospective interventional randomized controlled trial to assess safety and efficacy of rivaroxaban in pediatric patients with acute deep venous thrombosis.
- Trial name
- NCT07618988
- Testing
- Rivaroxaban, Enoxaparin, Heparin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Stroke
A RCT to Establish the Effectiveness of Intermittent Pneumatic Compression to Prevent Post Stroke DVT
Strokes occur when blood flow to part of the brain is interrupted. Patients are often bedbound for several days or weeks although if they survive, most will make some recovery.
- Trial name
- CLOTS-3 (NCT00789542)
- Testing
- Intermittent Pneumatic compression, Routine care
- Where
- United Kingdom
- Volunteers
- 2,876 people
- Sponsor
- University of Edinburgh
Venous Thromboembolism; Deep Vein Thrombosis; Pulmonary Embolism; Anticoagulants
VTE and the Related Factors Associated With Higher Rates of PE After a DVT in Southwestern China
Little is known about the current management status of venous thromboembolism (VTE) in Southwestern China. We aimed to investigate the status of anticoagulant administration in VTE in Southwestern China and assess the potential…
- Trial name
- NCT05464901
- Volunteers
- 500 people
- Sponsor
- Wei Huang
Deep Venous Thrombosis, Pulmonary Embolism
FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease
This is a multi-center prospective cohort study of patients with first-episode deep venous thrombosis and pulmonary embolism.
- Trial name
- NCT04583878
- Testing
- Blood draw (Visit 1), Blood draw (Visits 2 and 3)
- Where
- 14 sites in United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center