Clinical trials: Damage Control
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Other Injury of Other Intra-abdominal Organs, Initial Encounter
Damage Control Laparotomy
Randomized study to compare outcomes of patients undergoing damage control laparotomies versus definitive closure for which there is surgeon equipoise to randomize.
- Trial name
- NCT02706041
- Testing
- Definitive Closure Laparotomy, Damage Control Laparotomy
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Troublesome Sialorrhea, Cerebral Palsy
Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability
The objective of this study is to investigate the efficacy and safety of NT 201 compared with placebo for the treatment of chronic troublesome sialorrhea associated with neurological disorders (e.g.
- Conditions
- Chronic Troublesome Sialorrhea, Cerebral Palsy, Stroke, Traumatic Brain Injury
- Trial name
- SIPEXI (NCT02270736)
- Testing
- NT 201
- Where
- 31 sites in Georgia, Hungary and 4 more
- Volunteers
- 256 people
- Sponsor
- Merz Pharmaceuticals GmbH
Cerebral Palsy, Muscle Spasticity
Dysport® Pediatric Lower Limb Spasticity Study
The purpose of this research study is to determine whether Dysport® is effective in the treatment of increased stiffness of the calf muscles and to evaluate the safety of this treatment in children with Cerebral Palsy.
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Trial name
- NCT01249417
- Testing
- Botulinum toxin type A
- Where
- 29 sites in United States, Chile and 4 more
- Volunteers
- 241 people
- Sponsor
- Ipsen
Cerebral Palsy, Hemiplegia
Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy
A randomized control trial of bimanual training. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement therapy in children with…
- Conditions
- Cerebral Palsy, Hemiplegia, Children, Pediatric
- Trial name
- NCT00305006
- Testing
- Constraint-Induced Movement Therapy (CIMT), Hand-Arm Bimanual Intensive Therapy (HABIT)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Teachers College, Columbia University
To Determine Efficacy of the Headpod, Cerebral Palsy
Measuring Head Control Change With 2D Video Analysis After Utilization of Headpod in Children With Poor Head Control
Inclusion Criteria: children ages 2 to 14 years with poor head control and non progressive diagnoses. Exclusion criteria: significant change of status i.e. prolonged hospitalization, surgery; inability to tolerate using Headpod.
- Trial name
- headpod (NCT02764775)
- Testing
- Headpod
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Texas Woman's University
Cerebral Palsy, Exercise Therapy
RCT on Interactive Computer Play on Trunk Control in CP
Objectives: This proposal is to investigate the effect of a 6-week training programme using an Interactive computer play (ICP) on the trunk control, balance and gross motor function in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy, Exercise Therapy, Postural Balance
- Trial name
- NCT02975804
- Testing
- Tymo
- Where
- Hong Kong
- Volunteers
- 18 people
- Sponsor
- The Hong Kong Polytechnic University
Cerebral Palsy, Neuromuscular Scoliosis
Seating System for Scoliosis in Non-ambulatory Children With Cerebral Palsy: A Pilot Randomized Controlled Trial
The effect of a modular seating system on coronal and sagittal balance of the spine and pelvic obliquity in children with non-ambulatory (Gross Motor Function Classification System Level IV-V) and scoliosis The hypothesis in our…
- Trial name
- NCT03862625
- Testing
- a modular adaptive seating system, home exercise program for scoliosis
- Volunteers
- 30 people
- Sponsor
- Merve Damla Korkmaz
Cerebral Palsy
Contralaterally Controlled FES for Hand Opening in Hemiplegic Cerebral Palsy
This is a pilot randomized controlled trial of an intervention to improve arm function in children ages 6 to 17 with cerebral palsy and upper limb hemiparesis.
- Trial name
- NCT02925455
- Testing
- Contralaterally-controlled functional electrical stimulation, Hand therapy video games
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- MetroHealth Medical Center
Vegetative State, Minimally Conscious State
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- tDCS in DOC (NCT01673126)
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University of Liege
Pediatric Stroke, Cerebral Palsy
Repetitive TMS and Occupational Therapy in Children and Young Adults With Chronic Hemiparesis
The purpose of this study is to determine whether Repetitive Transcranial Magnetic Stimulation (rTMS) can augment occupational therapy in improving motor function in children (10 years of age or older) and young adults (< 21…
- Conditions
- Pediatric Stroke, Cerebral Palsy, Chronic Hemiparesis
- Trial name
- NCT02057276
- Testing
- Repetitive Transcranial Magnetic Stimulation, Occupational Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cerebral Palsy
Allogenic Umbilical Cord Blood and Erythropoietin Combination Therapy for Cerebral Palsy
This randomized control study is aimed to determine efficacy of umbilical cord blood and erythropoietin combination therapy for children with cerebral palsy.
- Trial name
- NCT01193660
- Testing
- Umbilical Cord Blood Infusion, Erythropoietin Injection, Active Rehabilitation
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Sung Kwang Medical Foundation
Cerebral Palsy, Postural; Defect
The Effect of Dynamic Elastomeric Fabric Orthosis (DEFO) on Sitting Balance and Gross Manuel Dexterity in Cerebral Palsy
To evaluate the effects and feasibility of lycra based compression garment called Stabilizing Pressure Input Orthosis (SPIO) vest on posture and balance during sitting and gross manuel dexterity, parent satisfaction with the…
- Trial name
- NCT03191552
- Testing
- SPIO, conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Marmara University
Cerebral Palsy
Quantifying Patient-Specific Changes in Neuromuscular Control in Cerebral Palsy
Impaired neuromuscular control hinders movement for individuals with cerebral palsy and other neurological disorders. In this research, the investigators are developing new tools to quantify impaired neuromuscular control in…
- Trial name
- NCT02699554
- Testing
- Single-event multilevel surgery
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Washington
Injury of Duodenum, Pancreatic Injury
Damage Control for Duodenal and Combined Duodenal-Pancreatic Injuries
The management of significant duodenal injuries and combined duodenal-pancreatic injuries continues to be challenging and controversial, and several techniques have been advocated over the years.
- Trial name
- NCT00937118
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Oregon Health and Science University
Autism Spectrum Disorder, Cerebral Palsy
READYorNot[TM] Brain-Based Disabilities Trial
The purpose of this study is to find out if there is a benefit to using the MyREADY Transition[TM] BBD App for brain-based disabilities, compared to not using it.
- Conditions
- Autism Spectrum Disorder, Cerebral Palsy, Epilepsy, Fetal Alcohol Spectrum Disorders
- Trial name
- NCT03852550
- Testing
- e-health application
- Where
- 9 sites in Canada
- Volunteers
- 52 people
- Sponsor
- McMaster University
Cerebral Palsy, CP
A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children With Cerebral Palsy
The purpose of this study is to determine the efficacy of a single intravenous infusion of autologous umbilical cord blood (UCB) for the treatment of pediatric patients with spastic cerebral palsy.
- Conditions
- Cerebral Palsy, CP, Spastic Cerebral Palsy
- Trial name
- NCT01147653
- Testing
- Autologous UCB Reinfusion
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Joanne Kurtzberg, MD
Cerebral Palsy
Intelligent and Adaptive Control Applied to Powered Walkers
The research is towards an advanced control and computer learning strategy that will intelligently drive a powered walker for people with walking disabilities.
- Trial name
- NCT05465239
- Testing
- SurePace Powered Walker User
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Barron Associates, Inc.
Spastic Cerebral Palsy
Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
The purpose of this proposal is to improve the investigators' current Selective Dorsal Rhizotomy (SDR) analgesia protocol by eliminating or minimizing the use of fentanyl in the post-operative period.
- Trial name
- NCT00955877
- Testing
- Extended-release Epidural morphine (EREM) 80, Extended-release Epidural Morphine (EREM) 120, Control: Saline
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Cerebral Palsy, Dyskinetic
A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Dyskinesia in Cerebral Palsy in Children and Adolescents
CP (cerebral palsy) refers to a group of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination.
- Trial name
- RECLAIM-DCP (NCT03813238)
- Testing
- TEV-50717
- Where
- 70 sites in United States, Belgium and 10 more
- Volunteers
- 63 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.