Clinical trials: Decayed Teeth
Dental Caries in Children
Different Methods for Reducing Buccal Infiltration Local Anesthesia Injection Pain
Local anesthetic injection is considered one of the most annoying dental procedures. The use of topical anesthesia is considered a routine procedure in the dental clinic especially for children.
- Trial name
- NCT06290531
- Testing
- Buzzy device (cold and vibration), Buzzy device (vibration only), precooling
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carious and Non-carious Lesions of the Teeth
Comparative Evaluation of Dental Disease Prevention Programs
Relevance. The dental health of the Chapaevsk children's population and the risk factors for dental caries and periodontal disease were well studied in 1995-2009.
- Trial name
- NCT05767281
- Testing
- prevention program
- Where
- Russia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Samara State Medical University
Dental Caries
Development and Validation of a Multi-Mineral Fluoride Mouthrinse
The primary goals of this project are to determine the anticaries benefits of a prototype multi-mineral mouthrinse containing 225 ppm fluoride and 30 ppm of a Ca through the remineralization of enamel white-spots (non-cavitated…
- Trial name
- NCT00642252
- Testing
- Fluoride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana Nanotech, LLC
Dental Caries in Children
Evaluation of Two Different Types of Zirconia Crowns Used in Carious Primary Anterior Teeth
Evaluation of two different types of zirconia crowns ( Kinder Krown , Nusmile crown) used in carious primary anterior teeth
- Trial name
- NCT05121584
- Testing
- Placement of an anterior crown restoration as a final restoration
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Arig Samir Abdelmonem Shawky
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries, Pulpotomy
BiodentineTM Versus Formocresol Pulpotomy Technique in Primary Molars
The objective of this clinical study was to prospectively compare the clinical and radiographic success rates of BiodentineTM pulpotomies versus formocresol pulpotomies in children vital primary molars.
- Trial name
- NCT03779698
- Testing
- BiodentineTM, Formocresol
- Where
- Saudi Arabia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Early Childhood Caries (ECC), Dental Caries Prevention
Evaluating the Effect of Xylitol Wipes on Cariogenic Bacteria in Infants and Toddlers
This clinical study evaluates whether cleaning infants' and toddlers' teeth and gums with xylitol-containing wipes can help reduce oral bacteria associated with early childhood caries.
- Conditions
- Early Childhood Caries (ECC), Dental Caries Prevention, Oral Bacterial Colonization, Pediatric Oral Health
- Trial name
- NCT07245433
- Testing
- Xylitol Dental Wipes
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Caries
Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings
The study aims to develop a questionnaire that can be used to help uncover a child's risk of developing dental caries (also known as tooth decay or a cavity).
- Trial name
- NCT01707797
- Where
- 3 sites in United States
- Volunteers
- 1,326 people, healthy volunteers welcome
- Sponsor
- University of Michigan
White Spot Lesion
P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions
Background: Great efforts have been undertaken for dental caries prevention. Among the recent remineralizing materials, Nano silver fluoride varnish products which are based on nanotechnology have been proposed for "repairing"…
- Trial name
- NCT04929509
- Testing
- self-assembling peptide, nanosilver fluoride varnish, sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Caries, Periodontal Diseases
Third Molar: Caries, Periodontal Desease and Quality of Life
Caries and periodontal disease are chronic diseases of the oral cavity. The incidence of caries and periodontal disease can vary depending on the position of the third molar, The aim of this study was to verify possible…
- Trial name
- NCT06081816
- Testing
- carie
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dental Caries
An in Vitro Evaluation of Antimicrobial Photodynamic Therapy on Deciduous Carious Dentin
Despite of the decline of dental caries, this disease is still common in polarized groups affecting children. Therefore, the aim of this randomized blind in vivo study was to compare the antimicrobial effect of two antimicrobial…
- Trial name
- NCT02479958
- Testing
- Rubber dam isolation, Tooth drying, Dentin wash with chlorhexidine 2%
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement
The objective of this randomized clinical trial is to evaluate the survival of restoration with high viscosity glass ionomer cement (HVGIC) with pre-etching with polyacrilic acid compared with no pre-etching in order to treat…
- Trial name
- CEPECO4 (NCT03785769)
- Testing
- HVGIC restoration with pre-etching, HVGIC restoration with non pre-etching
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
PreTerm Birth
Prevalence of Dental Caries in Preterm Birth Children Aged 2-5 Years in Primary Dentition
The purpose of the study is to determine the prevalence of dental caries in preterm birth children aged 2-5 years in primary dentition.
- Trial name
- NCT02999061
- Where
- Egypt
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Diabetes Mellitus, Sarcoidosis
Salivary Proteins in Disease and Health
This study will examine saliva samples from healthy volunteers and patients with various diseases to learn more about how disease affects the mouth and salivary glands.
- Conditions
- Diabetes Mellitus, Sarcoidosis, Dental Caries, Sjorgren's Syndrome
- Trial name
- NCT00100204
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dental Caries
Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children
The primary objective of this trial is to investigate the effect of a symbiotic lozenge on dental caries in young children.
- Trial name
- PiP-C (NCT03928587)
- Testing
- 2 billion CFU in total of the two strains Lactobacillus paracasei subsp. paracasei and Lactobacillus rhamnosus and arginine.
- Where
- Denmark
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Dental Caries in Children
Impact of Oral Health Program on Al-Lith Children's KAP
Dental caries remains a significant global public health issue, particularly affecting children's health, development, and well-being, with inadequate knowledge, attitudes, and practices around oral health exacerbating these…
- Trial name
- NCT07009015
- Testing
- The oral health education intervention program
- Where
- Malaysia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Dental Caries
Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction
This study compared four mouth rinses/chews for their ability to reduce Streptococcus Mutans after usage. The four that were compared were chlorhexidine gluconate (0.12%), sodium fluoride (0.05%), paraffin wax chewing gum (sugar…
- Trial name
- NCT02598778
- Testing
- Chlorhexidine gluconate (0.12%), Sodium Fluoride (0.05%), Paraffin wax chewing gum (sugar-free)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Dental Caries
On Probiotic, Dental Caries, and Orthodontic Patients
To investigate the short term effect of probiotic oil on plaque acidogenicity among orthodontic patients. Shortage on testing the effect of probiotic on Orthodontic patients can be seen on litterateurs making a gap of whether is…
- Trial name
- NCT04593017
- Testing
- Active Probiotic
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Dental Caries, Dental Fluorosis
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes
Fluoride toothpaste has been associated not only with declining dental caries prevalence but also with an increase in dental fluorosis.
- Trial name
- NCT01589991
- Testing
- Toothpaste
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil