Clinical trials: Deep Sedation
Pediatric Sedation
Lullaby vs White Noise vs Silence in Pediatric MRI Sedation
This prospective randomized study aims to evaluate the effects of three auditory conditions-lullaby music, white noise, and silent headphone use-on sedation depth, anesthetic drug requirements, and recovery outcomes in children…
- Trial name
- CALMMRI (NCT07325331)
- Testing
- Silent Headphone, White Noise, Lullaby Music
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Moderate, Deep Sedation
Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children
There is a wide variation of published IV ketamine dosing regimens used for procedural sedation in children in the Emergency Department (ED).
- Trial name
- NCT02519595
- Testing
- Ketamine IV 1mg/kg, Ketamine IV 1.5mg/kg, Ketamine IV 2mg/kg
- Volunteers
- 182 people
- Sponsor
- Children's Hospital of Michigan
Emergence Delirium in Pediatric Anesthesia
The Effect of Dormicum-Ketamine Versus Dexmedetomidine on Emergence Delirium During Deep Sedation in Paediatric Burn Patients
The aim of this study is to compare the effects of dormicum-ketamine versus dexmedetomidine on postoperative emergence delirium in pediatric patients undergoing deep sedation for burn-related procedures
- Trial name
- NCT07519863
- Testing
- Midazolam + Ketamine, Dexmedetomidine (DEX)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Respiration, Artificial, Critical Illness
Adjunctive Clonidine in the Sedation of Mechanically Ventilated Children
Almost all critically ill children who are mechanically ventilated require sedation and analgesia. Providing effective sedation for children in the PICU requires careful balancing of the need for sedation with the adverse effects…
- Conditions
- Respiration, Artificial, Critical Illness, Conscious Sedation, Deep Sedation
- Trial name
- NAPS Pilot (NCT00959062)
- Testing
- clonidine
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Hamilton Health Sciences Corporation
Oxygen Administration During Deep Sedation
Nasopharyngeal Versus Nasal Cannula Oxygen Supplementation in Surgery Patients
The investigators plan to conduct a randomized, controlled trial comparing nasopharyngeal oxygen supplementation to traditional nasal cannula in patients undergoing oral surgery under moderate sedation.
- Trial name
- NCT02219464
- Testing
- Nasopharyngeal catheter, Nasal Cannula, Oxygen Supplementation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University
Anesthesia, Surgery
Frontal Electroencephalography of Neonatal Patients Under Sedation With Opioids and General Anesthesia With Propofol.
Frequently, neonates hospitalized in neonatology units require anesthesia for surgery. The drugs used for this purpose are opioids and other anesthetics, such as propofol.
- Conditions
- Anesthesia, Surgery, Neonate, Depth of Anesthesia
- Trial name
- NCT04904965
- Testing
- Propofol Group 1, Propofol Group 2, Propofol Group 3
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Deep Sedation
Comparison of Oxygenation Methods in Sedation
Abstract Backgrounds and objectives: Dental treatments, especially in children who can not be cooperated, may require deep sedation due to intense anxiety and fear.
- Trial name
- NCT03893877
- Testing
- nasal cannula, nasal mask
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cerebral Palsy
Sevoflurane and Propofol for Botulinum Toxin Injection
The investigators would like to compare clinical features (onset, duration, emergence time), efficacy of deep sedation (successful completion of procedure), safety (adverse events) and caregiver's satisfaction for sedation when…
- Trial name
- NCT05505123
- Testing
- Sevoflurane, Propofol
- Where
- South Korea
- Sponsor
- Yeungnam University College of Medicine
Laryngoscopy, Child
Correlation Between Sedation Depth Monitoring and Reflexes During Intravenous Anesthesia With Dexmedetomidine and Remifentanil in Children Undergoing Direct Laryngoscopy for Surgical Procedures
This study evaluates the correlation between sedation depth monitoring obtained by NeuroSENSE ® NS 701 Monitor and reflexes during intravenous anesthesia in children undergoing direct laryngoscopy for surgical procedures.
- Conditions
- Laryngoscopy, Child, Monitoring
- Trial name
- NCT03426579
- Testing
- NeuroSENSE ®in children
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Antwerp
Respiratory Morbidity
Dexmedetomidine Sedation in Children With Respiratory Morbidities
This study aimed to determine the feasibility of dexmedetomidine in children with respiratory morbidities who required deep sedation for magnetic resonance imaging (MRI) scans.
- Trial name
- NCT02555605
- Testing
- Dexmedetomidine
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Universitair Ziekenhuis Brussel
Sedation
Sedation MRI - Propofol Versus Propofol-Ketamin in Children
Children < 10 years of age often need deep sedation or anaesthesia to allow elective diagnostic magnetic resonance imaging; standard routine protocols are 1.
- Trial name
- NCT01519154
- Testing
- Propofol, Ketamine-Propofol
- Where
- Switzerland
- Volunteers
- 347 people
- Sponsor
- Achim Schmitz
Analgesia, Deep Sedation
Implementation and Evaluation of a Pediatric Nurse-driven Sedation Protocol in a PICU
Management of analgesia and sedation is an integral component of the medical care of a critically-ill child. Its role is to assure comfort and safety to a patient undergoing painful cares and technical procedures; it can also be…
- Trial name
- SEDATIDE (NCT02829710)
- Testing
- Nurse-driven sedation protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Mental Retardation
Accurate Controlled Dental Sedation
The aim of this study is to evaluate benefits of the method of dental sedation using Target controlled infusion (TCI) combined with Bispectral index (BIS) monitoring in patients with Mental Retardation and challenging behavior.
- Trial name
- ACDS (NCT00963898)
- Testing
- Target controlled infusion(TCI), Bispectral index(BIS)
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Okayama University
Traumatic Brain Injury, Computed Tomography
Evaluation of Pediatric Procedural Sedation With Rectal Chloral Hydrate or Intranasal Midazolam
Thousands of children receive sedation for diagnostic and therapeutic interventions annually, and this number is expected to increase. Children are at higher risk for sedation-related complications than adults.
- Conditions
- Traumatic Brain Injury, Computed Tomography, Procedural Sedation
- Trial name
- NCT01402596
- Testing
- Midazolam, Chloral Hydrate
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Cerebral Palsy
The Effect of Bispectral Index Monitoring on Recovery From Deep Sedation
The purpose of this study was to compare BIS (bispectral index) monitoring and clinical sedation scale assessment on the recovery time and propofol usage from deep propofol sedation in children with cerebral palsy who received…
- Trial name
- NCT04190082
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Yeungnam University College of Medicine
Cerebral Palsy
Optimal Dose of Propofol for Induction of Deep Sedation for Brain MRI Scanning in Children With Cerebral Palsy
The children with CP has been shown different drug responses from the normal population of children and it may related with a various oral medications such as baclofen, tizanidine, diazepam, dantrolene, or anticonvulsant drugs.
- Trial name
- NCT01244113
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Procedural Sedation
EEG Spectral Pattern of Deep Sedation-induced Airway Adverse Effects
To investigate the associations bewteen the sedation level and the airway adverse effects by using the EEG, Airmod breath sound monitor and the capnography.
- Trial name
- NCT05595798
- Testing
- Airmod breathing sound monitoring
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Palliative Care, Deep Sedations
Prevalence of Deep Sedation in Terminal Palliative Phase
This nation-wide, multicentric, prospective and cross-sectional study aims to estimate the prevalence of deep sedations (i.e. with a -4 or -5 score at the Richmond scale at the induction time) for patients in terminal phase and…
- Trial name
- PREVAL-S2P (NCT04333719)
- Testing
- Type of sedations
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Bordeaux
Adrenal Insufficiency
Cortisol Response to Moderate and Deep Sedation in Children
Currently, it is unknown whether sedation itself induces a rise in serum cortisol levels or if cortisol levels rise under only the most invasive of procedures, regardless of the type of anesthetic agent used.
- Trial name
- NCT01265966
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Tripler Army Medical Center
Pediatric Sedation
Evaluation of the Efficacy of Oxygen Therapy and Clinical Feasibility of High Flow Nasal Cannula During Moderate and Deep Sedation in Pediatric Patients
The investigators evaluate the efficacy and safety of routine administration of oxygen during moderate or deep sedation in pediatric patients.
- Trial name
- NCT04852432
- Testing
- high flow nasal cannula, nasal prong
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Seoul National University Hospital