Clinical trials: Defibrillators
Defibrillators, Implantable, Cardiac Arrest
Electrical Safety of Implantable Cardioverter Defibrillators
Patients at risk of developing life-threatening heart rhythms may require the implantation of a small device called a cardioverter-defibrillator (ICD), which constantly monitors the heart rhythm and delivers an electrical shock…
- Trial name
- NCT03271619
- Testing
- Surface current measurement
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Sudden Cardiac Death, Sudden Cardiac Arrest
Low QRS Voltages in Young Healthy Individuals and Athletes
There is some limited evidence that reduced size of electrical complexes/traces of the heart on the electrocardiogram (ECG) may be associated with scarring in the heart muscle, which may predispose to serious life-threatening…
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Sudden Cardiac Death Due to Cardiac Arrhythmia, Arrhythmogenic Right Ventricular Cardiomyopathy
- Trial name
- NCT05799833
- Testing
- Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pacemaker, Defibrillators, Implantable
Complications Following Pacemaker or Implantable Defibrillator Cardioverter (ICD) Implantation in Denmark
This study examines possible risk factors with regard to complications following pacemaker or implantable defibrillator cardioverter (ICD) implantation.
- Trial name
- NCT01138670
- Where
- Denmark
- Volunteers
- 5,500 people
- Sponsor
- University of Aarhus
Depression, Anxiety
The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study
The introduction of pacemakers and implantable cardioverter-defibrillators (ICDs) has substantially changed the medical and surgical management of patients with cardiac rhythm disease.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- IDEAS (NCT01040988)
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Boston Children's Hospital
Heart Failure
Deutsches Device Qualitätsregister
It is the aim of this register to document the development of therapies by implantation of Cardioverter/Defibrillators (ICDs) and/or Cardiac Resynchronization therapy (CRT)-Systems.
- Trial name
- NCT01173783
- Where
- 7 sites in Germany
- Volunteers
- 4,008 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Out-Of-Hospital Cardiac Arrest
AED-delivery Using Drones in Out-of-hospital Cardiac Arrest
Time to defibrillation is the most important predictor of survival in cardiac arrest. Traditional emergency medical system response is often to slow.
- Trial name
- NCT04415398
- Testing
- Automated flying Drone carrying an Automated external defibrillator (AED)
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Patients With an Implanted S-ICD Who Continue to Exercise Regularly
Safety of Sports for Patients With a Subcutaneous Implantable Cardioverter Defibrillator
A multicenter observational study designed specifically to collect data on the safety of sport activities in patients with implanted S-ICD systems.
- Trial name
- SPORT-SICD (NCT05754138)
- Testing
- Sport SICD
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Eli Sprecher, MD
Cardiopulmonary Resuscitation
Optimization of Quality in Cardiopulmonary Resuscitation Through Monitor-defibrillator With Feedback System
AIM: To verify the effect of a feedback system on optimizing quality during CPR on mannequins. Hypothesis: The quality of CPR performed by healthcare professionals through a defibrillator monitor with a feedback system is higher…
- Trial name
- NCT04357548
- Testing
- FEEDBACK
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Pediatrics, Defibrillators, Implantable
Precise Measurement of Pediatric Defibrillation Thresholds
Patients who receive an implantable cardioverter-defibrillator (ICD) usually undergo testing at the end of the ICD procedure to measure the amount of energy able to successfully defibrillate the heart (defibrillation threshold…
- Trial name
- NCT01043562
- Testing
- Defibrillator threshold testing, Observation of post-shock intrinsic cardiac rhythm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Boston Children's Hospital
Pediatric Residents
Time to Defibrillation Using Automated External Defibrillators by Pediatric Residents in Simulated Cardiac Arrests
Automated external defibrillators have improved survival for adult in hospital cardiac arrest. Automated external defibrillators are approved for children aged 1 year and older for out of hospital cardiac arrests.
- Trial name
- NCT00640354
- Testing
- Automated external defibrillator, Manual defibrillator
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baylor College of Medicine
Performing Bioimpedance Analysis
BIA and Cardiac Implantable Electronic Devices
There are an increase number of patients with cardiac implantable electronic devices (CIEDs) such as pacemakers (PM) and implantable cardioverter-defibrillators (ICDs) worldwide.
- Trial name
- NCT03045822
- Testing
- Bioimpedance analysis
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Respiration, Artificial
Feasibility of Ventilation Detection Via Standard Defibrillator Pads in Mechanically Ventilated Pediatric Patients
This study is a prospective, observational case series of a convenience sample of mechanically ventilated pediatric patients in the Pediatric ICU, Progressive Care Unit and Operating Room at the Children's Hospital of…
- Trial name
- Vent Detection (NCT00628875)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Hospital of Philadelphia
Atrial Fibrillation, Defibrillators
Double Sequential External Defibrillation in Patients With Atrial Fibrillation Refractory to DC Cardioversion
Atrial fibrillation (AF) is a common cardiac arrhythmia that leads to increased risk of heart failure, hospitalization, thromboembolic events, and death.
- Conditions
- Atrial Fibrillation, Defibrillators, Persistent Atrial Fibrillation
- Trial name
- NCT03827915
- Testing
- Double sequential external defibrillation
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Arrhythmia, Cardiac
Japanese Lead Extraction Registry
Japanese Lead Extraction (J-LEX) Registry is an observational nationwide registry, performed by Japanese Heart Rhythm Society, collaborated with the National Cerebral and Cardiovascular Center.
- Trial name
- J-LEX (NCT04345627)
- Where
- Japan
- Volunteers
- 5,000 people
- Sponsor
- National Cerebral and Cardiovascular Center, Japan
Heart Failure, Ventricular Dysfunction
Austrian Wearable Cardioverter Defibrillator Registry
Background: The wearable cardioverter defibrillator (WCD) is an established treatment option for patients at high risk for ventricular tachycardia / ventricular fibrillation (VT/VF), either in whom this risk may only be…
- Conditions
- Heart Failure, Ventricular Dysfunction, Sudden Death, Sudden Cardiac Arrest
- Trial name
- NCT02816047
- Testing
- Registry
- Where
- Austria
- Volunteers
- 450 people
- Sponsor
- Medical University of Graz
Heart Block, Bradycardia
iPod and Other MP3 Players on ICDs and Pacemakers in Children
Unlike phones, which are commonly held to the ear, music is now available via portable MP3 players and they can be held almost anywhere.
- Conditions
- Heart Block, Bradycardia, Tachycardia, Arrhythmia
- Trial name
- NCT00542854
- Testing
- MP3
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Implantable Defibrillator User
Investigation of the Audible ICD Alert Tone
Ability of ICD patients to hear the audible ICD alert is being assessed.
- Trial name
- NCT06388382
- Testing
- Alert tone demonstration
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Universitätsklinikum Köln
HCM - Hypertrophic Cardiomyopathy, S-ICD System (implantable Defibrillator)
An Observational Study of Subcutaneous Implantable Cardioverter Defibrillator in Patients with Hypertrophic Cardiomyopathy At High Risk of Sudden Cardiac Death
1. To observe the failure rate of S-ICD screening in HCM patients at high risk of SCD. 2. To observe the incidence of IAS in HCM patients with S-ICD implantation and explore the related factors of IAS.
- Trial name
- NCT06604169
- Where
- China
- Volunteers
- 589 people
- Sponsor
- China National Center for Cardiovascular Diseases
Lead Extraction Procedures
Pacemaker and Defibrillator Lead Extraction Registry
Implanted cardiac devices are commonly used to treat a wide variety of heart diseases, including arrhythmias, cardiac resynchronization in select heart failure patients, and life threatening heart rhythms.
- Trial name
- NCT03847025
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Sudden Cardiac Arrest
HeartStart FRx Defibrillator Event Registry
This post market clinical follow-up study is a multi-center, non-randomized, unblinded, observational registry of the performance of the FRx Automated external defibrillator (AED) used in conjunction with electrodes with or…
- Trial name
- NCT04250857
- Testing
- HeartStart FRX
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Heartstream US LLC