Clinical trials: Deformity of Spine
Encephalopathy, Developmental Delay and Behavioral Changes
RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies
RCT for Intermittent versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies
- Conditions
- Encephalopathy, Developmental Delay and Behavioral Changes, Cord Tumor Compression or Instability, Cord Tethering or Malformation
- Trial name
- NCT00515359
- Testing
- Intermittent Propofol Sedation, Continuous Propofol Sedation
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Corewell Health West
Scoliosis
Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis
Scoliosis is a three-dimensional deformity affecting the orientation and position of the spine. Locally, the shape of the vertebra is also affected.
- Trial name
- NCT02434003
- Where
- 9 sites in United States, Canada and 4 more
- Volunteers
- 1,200 people
- Sponsor
- St. Justine's Hospital
Adolescent Idiopathic Scoliosis
Prospective Study of Motion Preservation Evaluation Below Fusions of the Spine in Adolescent Idiopathic Scoliosis
The purpose of this study is to evaluate the relationship of A) The distal fusion level B) The total length of fusion and the post-operative range of motion in the unfused vertebral segments below the fusion in patients with…
- Trial name
- POM (NCT01661998)
- Where
- 3 sites in United States
- Volunteers
- 273 people
- Sponsor
- Setting Scoliosis Straight Foundation
Early-Onset Scoliosis Deformity of Spine (Disorder), Idiopathic Scoliosis
Limited-efficacy Testing of Spring Distraction System (SDS) and Unilateral One-way Rod (MID-C) for Early Onset Scoliosis
The primary aim of this study is to investigate the limited efficacy of these innovative surgical solutions in treatment of Early Onset Scoliosis (EOS) in terms of maintaining reduction while maintaining spinal growth.
- Trial name
- UniPOWR (NCT04003233)
- Testing
- SDS, MID-C
- Where
- 2 sites in Netherlands
- Sponsor
- UMC Utrecht
Scoliosis, Kyphosis
Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study
This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side…
- Conditions
- Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
- Trial name
- NCT02998138
- Where
- 5 sites in United States
- Volunteers
- 880 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Total Hip Arthroplasty
In Patients With Hip Dysplasia, Mid-Term Lower Extremities and Spine After Hip Arthroplasty Natural Course
Patients with developmental hip dysplasia often present to the outpatient clinic in adulthood with hip pain due to progressive hip osteoarthritis.
- Trial name
- NCT06176612
- Testing
- total hip arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Bezmialem Vakif University
Spine Deformity
Perioperative Nutritional Status and Nutritional Support in Patients With Spinal Deformity
To investigate the nutritional status, nutritional support and postoperative complications of patients undergoing spinal orthopedic surgery during the perioperative period.
- Trial name
- NCT04968483
- Testing
- Data collection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Spine Deformity, Scoliosis
The Effect of Three-dimensional Exercise (Schroth Exercise) on Diaphragm Thickness in Adolescent Idiopathic Scoliosis Patients
Spinal deformity is common in childhood and adolescence, and can often present as scoliosis or increased thoracic kyphosis deformity with various etiologies.The diaphragm is the main respiratory muscle, and diaphragm contraction…
- Conditions
- Spine Deformity, Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence
- Trial name
- NCT06417944
- Testing
- Scoliosis study form, Scoliosis X-ray (orthorontgenogram), Pulmonary function test
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Spine Deformity, Idiopathic Scoliosis
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine deformity surgery across…
- Conditions
- Spine Deformity, Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis, Spondylolisthesis
- Trial name
- ASPIRE (NCT05071144)
- Where
- 10 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Spinal Deformity, Hemothorax Postoperative
Hemothorax Caused by Posterior Correction Surgery for Spinal Deformity
Owing to the development of instruments and surgical techniques, the number of spinal deformity correction surgeries has increased significantly.
- Trial name
- NCT05579834
- Testing
- posterior correction surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Gazi University
Central Core Disease, Centronuclear Myopathy
Molecular and Genetic Studies of Congenital Myopathies
In the Congenital Myopathy Research Program at Boston Children's Hospital and Harvard Medical School, the researchers are studying the congenital myopathies (neuromuscular diseases present from birth), including central core…
- Conditions
- Central Core Disease, Centronuclear Myopathy, Congenital Fiber Type Disproportion, Multiminicore Disease
- Trial name
- NCT00272883
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- Boston Children's Hospital
Scoliosis Idiopathic Adolescent, Chest Deformities
Sagittal Spine Balance in Patients With Chest Wall Deformity
Does the funnel deformity affects the sagittal balance of the spine? This question is a result of a Principal Investigator's novel observation, that in some cases restoring the correct balance reduce the distance between the…
- Trial name
- NCT07070609
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Pomeranian Medical University Szczecin
Adolescent Idiopathic Scoliosis (AIS)
Clinical and Biological Parameters in Adolescent Idiopathic Scoliosis
This single-center, observational, cross-sectional study aims to investigate the association between fecal calprotectin levels and clinical characteristics in adolescents with idiopathic scoliosis.
- Trial name
- NCT07900126
- Volunteers
- 83 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Postural Kyphosis, Spine
Reliability of PHAS in Postural Hyperkyphosis
This observational, cross-sectional study aims to evaluate the reliability of the Postural Habits and Awareness Scale (PHAS) in patients with postural hyperkyphosis.
- Conditions
- Postural Kyphosis, Spine, Assessment, Self
- Trial name
- NCT06907901
- Testing
- PHAS Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul University - Cerrahpasa
Scoliosis, Spine Deformity
Post-Hoc Cost-Utility Analysis of Ultrasound-Guided Erector Spinae Plane (ESP) Block Versus Total Intravenous Anesthesia (TIVA) in Posterior Scoliosis Correction Surgery: Evidence From the Egyptian EQ-5D-5L Value Set
Posterior scoliosis correction surgery is associated with sever postoperative pain that necessitate high perioperative opioid doses to alleviate pain .
- Trial name
- NCT07470567
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Bank Hospital
Paralytic Scoliosis, Pelvic Obliquity
Posterior Minimally Invasive Surgery for Treating Paralytic Scoliosis With Pelvic Obliquity in Children Following Spinal Cord Injury
This randomized controlled trial compares posterior minimally invasive correction surgery with conventional posterior spinal fusion for children with paralytic scoliosis and severe pelvic obliquity following spinal cord injury.
- Conditions
- Paralytic Scoliosis, Pelvic Obliquity, Spinal Cord Injury, Neuromuscular Scoliosis
- Trial name
- NCT07594574
- Testing
- Posterior Minimally Invasive Correction Surgery, Conventional Posterior Spinal Fusion
- Where
- China
- Volunteers
- 39 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis (AIS)
Real-World Effectiveness of Conservative Treatment in Idiopathic Scoliosis
This retrospective observational study aims to assess the real-world effectiveness of conservative treatment (bracing and specific exercises) in patients with idiopathic scoliosis treated with an Evidence-Based Personalised…
- Conditions
- Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis (AIS), Juvenile Idiopathic Scoliosis
- Trial name
- NCT07873554
- Testing
- Brace, Specific exercises (SEAS)
- Where
- Italy
- Volunteers
- 30,000 people
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Spinal Deformity
AI-Powered Scoliosis Auto-Analysis System Multicenter Development and Validations
The investigators aim to use artificial intelligence (AI) to help clinicians in diagnosing and assessing spinal deformities.
- Trial name
- NCT05146193
- Testing
- Nude back photo
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Scoliosis, Juvenile Idiopathic Arthritis
Spine Deformities in Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA)is the most common chronic rheumatic disease in childhood. While JIA usually affects the ankle and knee joints, it can also affect hip, cervical spine and shoulder involvement.
- Conditions
- Scoliosis, Juvenile Idiopathic Arthritis, Awareness
- Trial name
- Scoliosis (NCT04664231)
- Where
- Turkey (Türkiye)
- Volunteers
- 257 people
- Sponsor
- Biruni University
Adult Spinal Deformity
Influence of Sagittal Imbalance of the Spine on Gait Pattern in Adult Spinal Deformity
This study intends to investigate the changes in gait pattern in adult spinal deformity (ASD) patients with sagittal imbalance. It will investigate the gait kinematics in patients who have a mismatch of their spinopelvic…
- Trial name
- NCT03304405
- Testing
- Gait Analysis
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- The University of Hong Kong