Clinical trials: Deformity of Spine
Fibrinogen, Spine Deformity
Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery
EFISS is a prospective, randomized, placebo-controlled trial testing the feasibility, safety and efficacy of prophylactic administration of fibrinogen in paediatric spinal surgery.
- Conditions
- Fibrinogen, Spine Deformity, Coagulopathy, Consumption, Bleeding
- Trial name
- EFISS (NCT05391412)
- Testing
- Fibrinogen Concentrate Human
- Where
- Czechia
- Volunteers
- 32 people
- Sponsor
- Brno University Hospital
Sacroiliitis, Sacroiliac; Fusion
Evaluation of the iFuse Bedrock Technique in Association With Posterior Lumbosacral Fusion With Iliac Fixation.
The purpose of this study is to describe the impact of the iFuse Bedrock technique to decrease post-operative pains in patients who underwent multilevel posterior lumbosacral fusion.
- Conditions
- Sacroiliitis, Sacroiliac; Fusion, Lumbosacral; Fusion, Spine Deformity
- Trial name
- NCT05276024
- Testing
- iFuse Bedrock technique
- Where
- 2 sites in France
- Volunteers
- 48 people
- Sponsor
- Polyclinique Bordeaux Nord Aquitaine
Early-Onset Scoliosis Deformity of Spine
Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals
A hospital-based cluster stratified randomization control study will be conducted to investigate spinal growth in Early Onset Scoliosis patients between 5 and 9 years of age.
- Trial name
- MCGR (NCT04058561)
- Testing
- MAGEC® Spinal Bracing And Distraction System
- Where
- 20 sites in United States, Canada and 2 more
- Volunteers
- 210 people
- Sponsor
- Pediatric Spine Foundation
Spinal Muscular Atrophy, Spine Deformity
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects with spinal muscular atrophy (SMA).
- Conditions
- Spinal Muscular Atrophy, Spine Deformity, Scoliosis
- Trial name
- PIERRE (NCT05866419)
- Testing
- ThecaFlex DRx System
- Where
- 21 sites in United States, Germany and 3 more
- Volunteers
- 90 people
- Sponsor
- Alcyone Therapeutics, Inc
Spine Deformity, Idiopathic Scoliosis
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine deformity surgery across…
- Conditions
- Spine Deformity, Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis, Spondylolisthesis
- Trial name
- ASPIRE (NCT05071144)
- Where
- 10 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Spine Deformity, Bone Graft; Complications
ABM/P-15 Bone Graft vs Traditional Bone Graft in Adult Spinal Deformity Surgery
The purpose of this prospective trial is to investigate ABM/P-15 bone graft versus traditional bone graft in patients undergoing surgery for Adult Spinal Deformity (ASD) in order to provide better clinical results through faster…
- Conditions
- Spine Deformity, Bone Graft; Complications, Adverse Events
- Trial name
- NCT05038527
- Testing
- ABM/P-15 bone graft
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spine Deformity, Adult Scoliosis
The Effect of Peloidotherapy in Young Adults Undergoing Physical Therapy Scoliosis Specific Exercises (PSSE)
Scoliosis is a musculoskeletal disorder defined by a three-dimensional spinal deformity that can result in substantial clinical and functional limitations, particularly during adolescence and young adulthood.
- Conditions
- Spine Deformity, Adult Scoliosis, Peloidotherapy
- Trial name
- NCT07459400
- Testing
- Adult Scoliosis Study Form, Scoliosis graphy, Visuel Aanalog Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Spine Degeneration, Spine Spondylosis Thoracic
Clariance ErYs Registry
International, prospective, single arm, multicenter and observational Post-Market Clinical Follow-up (PMCF). The overall objective of this study is to collect preoperative, intraoperative and postoperative (at 9 weeks, 6 months…
- Conditions
- Spine Degeneration, Spine Spondylosis Thoracic, Spinal Deformity, Spinal Tumor
- Trial name
- ErYs (NCT05170815)
- Testing
- Spine surgery
- Where
- France
- Volunteers
- 760 people
- Sponsor
- Clariance
Scoliosis, Spine Deformity
Post-Hoc Cost-Utility Analysis of Ultrasound-Guided Erector Spinae Plane (ESP) Block Versus Total Intravenous Anesthesia (TIVA) in Posterior Scoliosis Correction Surgery: Evidence From the Egyptian EQ-5D-5L Value Set
Posterior scoliosis correction surgery is associated with sever postoperative pain that necessitate high perioperative opioid doses to alleviate pain .
- Trial name
- NCT07470567
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Bank Hospital
Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
Casting vs Bracing for Idiopathic Early-Onset Scoliosis
Comparison of casting and bracing for the treatment of idiopathic early onset scoliosis
- Trial name
- CVBT (NCT04500041)
- Testing
- Casting, Bracing
- Where
- 26 sites in United States, Italy and 1 more
- Volunteers
- 71 people
- Sponsor
- University of Iowa
Neuromuscular Scoliosis, Spine Deformity
Mini-invasive Spine Surgery for Neuromuscolar Scoliosis
Neuromuscular scoliosis (SNM) are deformities related to the impairment of normal function of the central nervous system (CNS) and/or peripheral nervous system (PNS) resulting in alterations to the of the functional unit…
- Conditions
- Neuromuscular Scoliosis, Spine Deformity, Surgery, Vertebral Fusion
- Trial name
- MISNM (NCT06367933)
- Testing
- mini-invasive spine surgery
- Where
- Italy
- Volunteers
- 1 people
- Sponsor
- Istituto Ortopedico Rizzoli
Spine Deformity, Kyphosis
The Effect of Three-Dimensional Exercises ( Schroth Method ) on Trunk Muscle Endurance, Sleep Quality, and Quality of Life in Adolescents With Hyperkyphosis
Adolescence is a critical period for spinal growth, and progression of thoracic hyperkyphosis may lead to pain, weak trunk muscles, sleep disturbances, and reduced quality of life.
- Conditions
- Spine Deformity, Kyphosis, Adolescent, Sleep Quality
- Trial name
- NCT07261358
- Testing
- Kyphosis Study Form, Scoliosis X-ray (Orthoroentgenogram), Inclinometer Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Spinal Fusion, Deformity of Spine
Pelvic Fixation and Fusion During Multilevel Spinal Surgery
PAULA aims to collect data on the safety, performance, and effectiveness of iFuse Bedrock Granite (GRANITE) in patients who have spinal fusion surgery with pelvic fixation/ fusion.
- Trial name
- PAULA (NCT05640908)
- Testing
- iFuse Bedrock Granite Implant System
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- SI-BONE, Inc.
Scoliosis, Spine Deformity
Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis
Idiopathic scoliosis of developmental age (AIS) is the most vertebral deformity in the adolescent population, with a prevalence of 1-3%.
- Conditions
- Scoliosis, Spine Deformity, Adolescent Idiopathic Scoliosis
- Trial name
- BS23 (NCT06396286)
- Testing
- single rod
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Disorder, Kyphosis Deformity of Thoracic Spine
Reliability of the Smartphone Inclinometer App and Flexicurve
The presedent study evaluates intra-rater and inter-rater reliability of the Smartphone inclinometer app and the flexicurve, on the thoracic kyphosis
- Trial name
- Sİ-FC (NCT05295550)
- Testing
- Realibility
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Hyperkyphosis, Spine Deformity
Ultrasonographic Measurement of Diaphragmatic Thickness in Adolescents With Thoracal Hyperkyphosis
Spinal deformity is common in childhood and adolescence. Any spinal deformity, especially one that affects the thoracic spine, can affect lung function.The diaphragm is the main respiratory muscle, and diaphragm contraction is…
- Conditions
- Hyperkyphosis, Spine Deformity, Diaphragm Issues
- Trial name
- NCT06418334
- Testing
- Thoracal hyperkyphosis study form, Scoliosis graphy, Pulmonary function test
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Adult Scoliosis, Spine Deformity
Perioperative Morbidity in Adult Scoliotic Surgery: Analysis of a Series From Brest (MOSCA-B)
Scoliosis surgery is an invasive procedure essential for alleviating significant pain and improving the physical, psychological, aesthetic, professional, and social well-being of patients.
- Conditions
- Adult Scoliosis, Spine Deformity, Neurosurgery
- Trial name
- MOSCA-B (NCT06815861)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Brest
Spine Deformity, Idiopathic Scoliosis
Implementation of Momentum SpineTM: a New 3D Imaging Software for Idiopathic Scoliosis
Brief Summary The goal of this clinical trial is to evaluate the implementation of Momentum Spine™, a new 3D imaging software designed to improve the monitoring and management of idiopathic scoliosis in children aged 8-14 years.
- Trial name
- NCT06777992
- Testing
- Home topographic scans
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Spine Deformity, Scoliosis
The Effect of Three-dimensional Exercise (Schroth Exercise) on Diaphragm Thickness in Adolescent Idiopathic Scoliosis Patients
Spinal deformity is common in childhood and adolescence, and can often present as scoliosis or increased thoracic kyphosis deformity with various etiologies.The diaphragm is the main respiratory muscle, and diaphragm contraction…
- Conditions
- Spine Deformity, Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence
- Trial name
- NCT06417944
- Testing
- Scoliosis study form, Scoliosis X-ray (orthorontgenogram), Pulmonary function test
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Spine, Spine Deformity
Evaluating and Establishing the Relationship in the Five Critical X-ray Time Points in Spinal Deformity Realignment
To establish the relationship in the five critical X-ray time points during multilevel posterior column osteotomies (MPCO) spinal deformity realignment in patients with adult spinal deformity and to follow the participants…
- Trial name
- NCT05154825
- Testing
- Imaging-Observational
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego