Clinical trials: Dementia Prevention
Diabetes, Alzheimer Disease
The Diabetes Prevention Program Outcomes Study AD/ADRD Project
The DPPOS AD/ADRD project will address the overarching question: What are the determinants and the nature of cognitive impairment among persons with pre-diabetes (PreD) and type 2 diabetes (T2D), who are a high-risk group for…
- Conditions
- Diabetes, Alzheimer Disease, Dementia, Vascular, Dementia
- Trial name
- DPPOS-4 (NCT05704309)
- Where
- 27 sites in United States
- Volunteers
- 1,976 people, healthy volunteers welcome
- Sponsor
- Marinella Temprosa
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dementia, Pain
Aggression Prevention Training for Caregivers of Persons With Dementia (APT)
This study will evaluate whether a home-based targeted education and skill training (Aggression Prevention Training or APT) will reduce aggression in persons with dementia (PWD) and pain/pain-related features more than usual care…
- Conditions
- Dementia, Pain, Alzheimer's Disease, Aggression
- Trial name
- APT (NCT02380703)
- Testing
- Aggression Prevention Training (APT), Enhanced Usual Primary Care (EU-PC)
- Volunteers
- 239 people
- Sponsor
- Baylor College of Medicine
Aggression
Multi-Site Evaluation of Second Step
This study is a large-scale, randomized longitudinal evaluation of Second Step: Student Success Through Prevention (Second Step - SSTP), a middle school intervention (Committee for Children, 2008), which targets the shared…
- Trial name
- SSTP (NCT01792167)
- Testing
- Second Step Curriculum
- Where
- United States
- Volunteers
- 4,089 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Dementia Prevention
e-Learning About Cognitive Impairment and Dementia Prevention
In this proposal, the investigators plan to study the effectiveness of our web-based intervention on dementia prevention knowledge, intentions, and behaviour change.
- Trial name
- NCT05383118
- Testing
- Education Intervention, Education Control
- Where
- Canada
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- McMaster University
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Aggression
NIH R01 Friend to Friend With Coaching
This study examines the effectiveness of the Friend to Friend (F2F) program when conducted by teachers and counselors with active coaching from the research team.
- Trial name
- NCT04164472
- Testing
- Friend to Friend (F2F) with Coaching
- Where
- United States
- Volunteers
- 5,250 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
PTSD, Depression
Violence Prevention for Adolescent Girls With Prior Maltreatment
The purpose of the study is to adapt and test an evidence-based trauma treatment program for adolescent girls with histories of child maltreatment.
- Conditions
- PTSD, Depression, Aggression, Victimization
- Trial name
- GAIN (NCT02765048)
- Testing
- GAIN Program
- Where
- 3 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Accidental Falls
The HIP-HOP Flooring Study: Helping Injury Prevention in Hospitalised Older People
In hospitals, older people can fall and hurt themselves. The investigators want to see if a new type of flooring can help stop people hurting themselves as badly, if they accidentally fall.
- Trial name
- NCT00817869
- Testing
- New flooring
- Where
- 8 sites in United Kingdom
- Volunteers
- 571 people
- Sponsor
- University of Portsmouth
Alzheimer Disease or Associated Disorder, Mild to Moderately Severe Dementia
Effectiveness of Care Management in Alzheimer Patients
Context: The French Alzheimer plan 2008-2012 includes the implementation of "disease managers" or social workers, from the onset of the disease, for every patient with a diagnosis of Alzheimer disease or associated disorder.
- Trial name
- AIDALZ (NCT01081743)
- Testing
- Intervention of the social worker
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Institut de Sante Publique, d'Epidemiologie et de Developpement
Violence, Adolescent
Addressing Root Causes for Gun Violence Prevention (ARC-GVP)
The goal of this study is to help build the evidence base for a locally-relevant youth firearm violence prevention program in Washington D.C., a city experiencing disparities in youth firearm violence outcomes.
- Conditions
- Violence, Adolescent, Firearm Injury, Aggression
- Trial name
- NCT05887973
- Testing
- The T.R.I.G.G.E.R Project
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Fighting Behavior, Aggression
Community-Based Violence Prevention for High-Risk Youth
Study Aims: 1) Assess the receptiveness of youth and families to injury prevention interventions initiated from the emergency department; 2) In a sample of high risk youth presenting to the ED with interpersonal assault injuries…
- Trial name
- NCT00444197
- Testing
- Mentoring and violence prevention curriculum with parental monitoring
- Where
- 2 sites in United States
- Volunteers
- 198 people
- Sponsor
- Johns Hopkins University
Dementia Prevention
Dementia Prevention Internet-Based Intervention: Randomized Controlled Trial and Knowledge Translation
In this proposal, the investigators plan to study the effectiveness of a web-based intervention on dementia prevention knowledge, intentions, and behaviour change related to dementia risk.
- Trial name
- NCT06911047
- Testing
- Education Intervention, Education Control
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Dementia
A Comprehensive Fall Prevention System for Memory Care: Final Feasibility and Randomized Controlled Study
This study tests novel technology using computer vision and remote clinical review to reduce falls for residents with dementia in assisted living communities.
- Trial name
- NCT04478149
- Testing
- SafelyYou, Control
- Volunteers
- 300 people
- Sponsor
- SafelyYou
Psychomotor Agitation
Does Intraoperative Clonidine Reduce Post Operative Agitation in Children?
Clonidine is widely used off-label in children for several indications. Clonidine is used for treatment and/or prevention of postoperative agitation in children anaesthetised with Sevoflurane.
- Trial name
- NCT02361476
- Testing
- Clonidine
- Where
- 3 sites in Denmark
- Volunteers
- 379 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Agitation, Child
Effects of Preoperative Using of Eye Patches on Prevention of Emergence Agitation After Cataract Surgery
This study is a single-center, prospective, randomized, controlled trial. To investigate if preoperative using of eye patch will decrease emergence agitation, and to provide a better method of decreasing emergence agitation to…
- Conditions
- Agitation, Child, Anesthesia
- Trial name
- NCT02590744
- Testing
- eye patch, non-eye patch
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xiaoliang Gan
Suicide, Aggression
Social Ecology and the Prevention of Suicide and Aggression in African American Youth
The purpose of this study is to examine the efficacy of a culturally-grounded, school-based suicide and aggression preventive intervention for African American adolescents (Adapted-Coping with Stress Course [A-CWS]).
- Trial name
- NCT03954457
- Testing
- A-CWS, Standard Care Control
- Where
- United States
- Volunteers
- 939 people, healthy volunteers welcome
- Sponsor
- DePaul University
Agitation
Nalbuphine Versus Dexmedetomidine for Prevention of Emergence Agitation in Pediatrics
the investigators hypothesized that Nalbuphine may be alternative pharmacological agent for prevention of emergence agitation in pediatrics who will be scheduled for elective lower abdominal surgical procedures (inguinal hernia…
- Trial name
- NCT05273671
- Testing
- Nalbuphine, Dexmedetomidine, normal Saline
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Alexandria University
Aggression
Healthy Brains & Behavior: Understanding and Treating Youth Aggression
Understanding the joint neurobiological and social bases to aggression is critical to future attempts to tackle this major public health problem.
- Trial name
- HBB (NCT00842439)
- Testing
- CBI, NUT
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dating Violence
The Effect of an Intervention Based on Implicit Theories of Personality on the Prevention of Adolescent Dating Violence
This study evaluates the efficacy of an intervention based on the Implicit Theories of Personality (ITP) to prevent dating violence in Spanish adolescents.
- Trial name
- NCT03583645
- Testing
- Incremental theory of personality, Educational Intervention
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- University of Deusto