Clinical trials: Dental Pulp Exposure
Irreversible Pulpitis (Toothache)
Laser Assisted Pulpotomy Versus MTA Pulpotomy in Permanent Teeth With Irreversible Pulpitis
This study compares two methods used during full pulpotomy, a treatment for teeth with deep tooth decay that has exposed the dental pulp.
- Trial name
- NCT07761962
- Testing
- Diode laser full pulpotomy, Sodium hypochlorite pulpotomy
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Molar Hypomineralization
Pulpotomy in Hypominerlized Permanent Molars.
The first permanent molars in children can sometimes develop a condition called molar-incisor hypomineralization (MIH), which affects the strength and quality of the tooth structure.
- Trial name
- NCT07756216
- Testing
- Step wise pulpotomy
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulpotomy
Assessment of Pulpotomy Procedure Using NeoMTA Plus in Permanent Teeth With Carious Exposure
Many deep carious teeth are treated unnecessarily by root canal therapy, while with using current techniques and advances in compatible dental materials in addition to better understanding of biological response of the dental…
- Trial name
- PULPOTOMY (NCT03522051)
- Testing
- calcium silicate based material,
- Where
- Jordan
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Carious Exposure of Pulp
New Vital Pulpotomy Medications in Primary Molars
Evaluate clinically and radiographically the effect of biodentine and hyaluronic acid (HA) versus formocresol (FC) as pulpotomy medications in primary molars.
- Trial name
- NCT05937100
- Testing
- Formocresol, Biodentine, Hyaluronic acid gel
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulp Exposure, Dental
Pulpotomy Technique Preserving Vitality of Traumatized Anterior Permanent Immature Teeth
Aim of the study: To compare the clinical and radiographic outcomes of mineral trioxide aggregate (MTA) and Biodentine as vital pulp therapy materials (pulpotomy) preserving the vitality of traumatized immature anterior permanent…
- Trial name
- NCT03838068
- Testing
- Biodentine, mineral trioxide aggregate, cervical pulpotomy
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Gihan M Abuelniel ,PhD
Dental Caries Extending Into Dentin
Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth
The sample will be, at least, 90 primary molars, randomly distributed into three groups: Group 1: IPC; Group 2: SE; Group 3: SCR.
- Trial name
- Caries_removal (NCT03650647)
- Testing
- Carious dentin removal
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq
Caries, Dental
Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy
The aim of this randomized controlled trial is to compare partial pulpotomy treatments with Biodentine®, calcium hydroxide (CH) and Mineral Trioxide Aggregate (MTA) in cariously exposed asymptomatic young permanent teeth…
- Trial name
- NCT03426046
- Testing
- Partial Pulpotomy, Pulp Capping Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali
Traumatic Pulp Exposure in Children
Clinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant Teeth
The aim of the study is to evaluate clinical and radiographic effect of nano propolis and nano curcumin as direct pulp capping agents in young permanent teeth. .
- Trial name
- NCT06029023
- Testing
- MTA Cement, propolis nano particle, curcumin nanoparticles
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Caries, Dental Pulp Exposure
Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Background: Dental caries is considered an oral health problem worldwide. In Chile the last national epidemiological study (2007) showed a national prevalence of dental caries in children 6 years (70.3%) and 12 (62.5%).
- Trial name
- NCT02492841
- Testing
- Mineral trioxide aggregate, Calcium hydroxide, Biodentine
- Where
- Chile
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Dental Pulp Exposure
Human Pulpal Response After Pulp Capping With Four Different Agents
Application of four different pulp capping methods on human sound premolars after intentional exposure of the buccal pulp horn through a class one occlusal cavity.
- Trial name
- NCT01468480
- Testing
- Pro Root MTA, Pro Root MTA- single visit, MultiCal
- Where
- Iran
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Carious Exposure of Pulp
Evaluation of MTA Versus Biodentine as Pulpotomy Agents in Immature First Permanent Molars
Aim of the study: To compare the clinical and radiographic outcomes of mineral trioxide aggregate (MTA) and Biodentine as vital pulp therapy materials (pulpotomy) of cariously exposed vital immature mandibular first permanent…
- Trial name
- NCT03838094
- Testing
- Biodentine, MTA
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gihan M Abuelniel ,PhD
Deep Caries
Direct Pulp Capping Compared to Partial Pulpotomy in Carious Pulp Exposures
This a prospective randomized clinical trial that compare vital pulp therapy procedures in permanent teeth with carious pulp exposure.
- Trial name
- Pulp cap (NCT06495242)
- Testing
- Direct pulp capping and partial pulpotomy
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Carious Exposure of Pulp
A Comparative Clinical and Radiographic Study of Collagen Based Pulpotomy Versus Biodentine Pulpotomy in Children With Cariously Exposed Vital Primary Molars
Pulpotomy of vital primary molars is indicated when caries removal results in pulp exposure. Treatment approaches consist of devitalization using formocresol, preservation using ferric sulfate and regeneration of the remaining…
- Trial name
- NCT05479877
- Testing
- sterile medicated collagen particles, Biofil-AB ,Eucare Pharmaceuticals Pvt. Ltd, Chennai, India, Biodentine (Septodont, Saint-Maur-des-Fossés, France)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Vital Pulp Therapy
Diagnostic Biomarkers to Correlate Molecular Changes and Inflammatory Cascade in the Dental Pulp.
This study aimed to evaluate the molecular changes that occur within the pulp tissue during inflammation and its correlation with vital pulp therapy with its different treatment modalities (Direct pulp capping, Partial Pulpotomy…
- Trial name
- NCT05464797
- Testing
- Pulp therapy, Cytokines level in pulpal blood.
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Carious Exposure of Pulp, Irreversible Pulpitis
Comparative Study of the Outcome of Partial and Full Pulpotomy in Irreversible Pulpits
This study aims at comparing the outcome of partial pulpotomy and full pulpotomy in the management of carious pulp exposures in permanent teeth with a clinical diagnosis of irreversible pulpits.
- Conditions
- Carious Exposure of Pulp, Irreversible Pulpitis, Pulpotomy
- Trial name
- NCT05279820
- Testing
- Partial pulpotomy, Full Pulpotomy
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pulp Exposure, Dental
Biodentine Vital Pulpotomy in Immature Molars
This study aimed to evaluate the clinical and radiographic success of pulpotomy in cariously exposed vital immature first permanent molars using calcium hydroxide and calcium silicate-based material (Biodentine ™).
- Trial name
- NCT04989036
- Testing
- pulpotomy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Pulp Exposure
Pulp Capping With Two Different Agents
The purpose of this study is to determine if MTA or calcium hydroxide are more effective as pulp capping agents
- Trial name
- MTA (NCT00812877)
- Testing
- Mineral Trioxide Aggregate, Calcium Hydroxide
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Carious Teeth
Outcome of Full Pulpotomy Using Calcium Silicate Based Materials
Permanent teeth with carious pulp exposure and indicated for full pulpotomy will be treated using three different materials using aseptic technique and will be subsequently followed up clinically and radiographically at 6 months…
- Trial name
- pulpotomy (NCT04345263)
- Testing
- MTA pulpotomy
- Where
- 2 sites in Jordan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology