Clinical trials: Deprivation
Epilepsy
Activating Effects of Sleep Deprivation on Synchronized MEG-EEG Recordings of Epilepsy Patients With Non-Diagnostic EEG
This study will evaluate how the state of being completely deprived of sleep has an effect on recordings of magnetoencephalography (MEG) and electroencephalography (EEG), in relation to how alert someone is and how sleepy someone…
- Trial name
- NCT00071370
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Apgar; 0-3 at 1 Minute, Metabolic Acidosis
Autologous Stem Cells in Newborns With Oxygen Deprivation
The purpose of this study is to determine whether the plasticity of autologous intravenous application of cord blood stem cells would improve the clinical course of asphyxiated newborns.
- Conditions
- Apgar; 0-3 at 1 Minute, Metabolic Acidosis, Hypoxia, Brain, Multiple Organ Failure
- Trial name
- NCT01506258
- Testing
- Application of Stem Cells, Observation
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Sleep Deprivation
The Effects of Night Call on Intellectual Performance
The purpose of the current proposal will be to examine the clinical performance of both physicians in training as well as experienced faculty in pre and post call situations.
- Trial name
- NCT02697266
- Testing
- No intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Haleh Saadat
Fibrolamellar Carcinoma, Fibrolamellar Liver Cancer
Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)
There is no effective standard treatment for fibrolamellar liver cancer that cannot be removed by surgery. The investigators want to find out what effects, good and/or bad, 3 drugs called letrozole, leuprolide and everolimus will…
- Trial name
- NCT01642186
- Testing
- everolimus, letrozole plus leuprolide, combination of everolimus, letrozole and leuprolide
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Depressive Disorder, Major, Bipolar Depression
Triple Chronotherapy in Adolescents
Study Purpose This study is a randomized controlled trial examining the effectiveness of TCT in the acute treatment of depression and suicidality in adolescents compared to usual treatment care, which includes individual and…
- Conditions
- Depressive Disorder, Major, Bipolar Depression, Suicidal Ideation
- Trial name
- TCT-RCT (NCT03679962)
- Testing
- Triple Chronotherapy, Treatment as Usual
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Billings Clinic
Osteoporosis
Changes in Bone Mineral Density and Fracture Risk in Patients Receiving Androgen Deprivation Therapy for Prostate Cancer
The aim of this study is to determine the long term effects of two types of hormonal treatment for advanced prostate cancer (LHRH agonists and the antiandrogen bicalutamide)on the bone mineral density of patients.
- Trial name
- NCT00536653
- Testing
- Bicalutamide and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate) and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate)
- Where
- United Kingdom
- Volunteers
- 618 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Social Deprivation
Social Deprivation and Postoperative Mortality
Socioeconomic factors are associated with differences in health outcomes, but their impact on surgical patients is still not well understood, especially in low- and middle-income countries.
- Trial name
- NCT07621211
- Where
- 7 sites in Brazil
- Volunteers
- 45,000 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Prostate Cancer
Changes in Brown Adipose Tissue Activity In Men Receiving Androgen Deprivation Therapy for Prostate Cancer
Androgen deprivation therapy (ADT) is considered standard of care for prostate cancer. However, changes in the patients metabolism are usually seen as a result of hormone therapy.
- Trial name
- NCT01226888
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Prostate Adenocarcinoma
Supportive Therapy in Androgen Deprivation Clinic in Improving Health Outcomes and Managing Side Effects in Patients With Prostate Cancer
This pilot partially-randomized phase II trial studies how well Supportive Therapy in Androgen Deprivation (STAND) clinic works in improving health outcomes and managing side effects in patients with prostate cancer.
- Trial name
- NCT02168062
- Testing
- Behavioral Dietary Intervention, Counseling, Educational Intervention
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Osteoporosis
Frequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate Cancer
The aim of this study is to determine if 3 monthly infusions of zoledronic acid, given over one year, improves the bone mineral density in osteoporotic patients undergoing androgen deprivation therapy for prostate cancer
- Trial name
- NCT00520052
- Testing
- zoledronic acid
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Diabetes Insipidus, Primary Polydipsia
Use of Copeptin in Diabetes Insipidus
Prospective evaluation of the novel biomarker copeptin in the differential diagnosis of diabetes insipidus against the standard diagnostic test methods.
- Trial name
- NCT01940614
- Testing
- Water deprivation test, Hypertonic saline infusion
- Where
- Switzerland
- Volunteers
- 156 people
- Sponsor
- University Hospital, Basel, Switzerland
Sleep Deprivation
The Function of Biphasic Sleep in Infants
This study is designed to investigate developmental changes in naps and nap function on memory from 9 to 15 months of age. Memory is measured by a task in which the experimenter interacts with a toy and the measure of memory is…
- Trial name
- NCT06399939
- Testing
- Nap, Wake
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Food Deprivation, Obesity, Childhood
Improving Participation in Universal School Meals (USM)
The purpose of this study is to assess the impact of an implementation strategy on participation in Universal School Meals (USM).
- Trial name
- NCT06579079
- Testing
- Implementation Mapping, Waitlist Comparison - Implementation Mapping
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Temple University
Tissue Oxygenation
Tissue Oxygen Deprivation as Detected With Raman in Association With Umbilical Artery Catheters
Umbilical artery catheters (UACs) are associated with significant morbidity in preterm neonates however are necessary for the management of this high risk population.
- Trial name
- NCT04038203
- Testing
- Resonance Raman Spectroscopy (RPS)
- Where
- United States
- Sponsor
- University of Florida
Sleep, Sleep Disturbance
Sleep Promotion Program Primary Care
Investigators developed a brief, scalable, behavioral Sleep Promotion Program (SPP) for adolescents with short sleep duration and sleep-wake irregularity, which relies on two individual sessions and smart phone technology to…
- Conditions
- Sleep, Sleep Disturbance, Insufficient Sleep
- Trial name
- SPP PC (NCT06240325)
- Testing
- SPP, Sleep Psychoeducation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Type 1, Diabetes
Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes
What are the effects of transient insulin deprivation on brain structure, blood flow, mitochondrial function, and cognitive function in T1DM patients? What are the effects of transient insulin deprivation on circulating exosomes…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes, Diabetes Complications
- Trial name
- NCT03392441
- Testing
- Insulin Deprivation in Type 1 Diabetic Patients
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prostate Cancer, Hormone Sensitive Prostate Cancer
Evaluation of Clinical Outcomes of Chemotherapy or Androgen-receptor Targeting Agent (Alone or Combined) or Radiotherapy on Primary Tumor in Addition to Androgen Deprivation Therapy in HOrmone-Sensitive Metastatic Prostate Cancer Patients
The aim of this observational study is to evaluate the clinical outcomes of treatment with docetaxel, ARTA (alone or in combination) or with radiotherapy on the primary tumor for mCSPC, in an unselected population, in clinical…
- Conditions
- Prostate Cancer, Hormone Sensitive Prostate Cancer, Metastatic Tumor
- Trial name
- ECHOS (NCT06473259)
- Testing
- Docetaxel, Apalutamide Oral Tablet, Enzalutamide Oral Tablet
- Where
- 3 sites in Italy
- Volunteers
- 3,000 people
- Sponsor
- Santa Chiara Hospital
Insufficient Sleep Syndrome, Inadequate Sleep Hygiene
Impact of Beds for Kids Program on Child Sleep
The primary objective of this study is to evaluate the impact of provision of a child bed through the Beds for Kids program on objectively measured child sleep, and on daily child behavioral functioning and caregiver functioning…
- Conditions
- Insufficient Sleep Syndrome, Inadequate Sleep Hygiene, Child Behavior Problems, Emotional Stress
- Trial name
- NCT03392844
- Testing
- Beds for Kids program
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Premature Infant, Patent Ductus Arteriosus
Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.
The proposed research evaluates tissue oxygenation (StO2) as measured by resonance raman spectroscopy (RRS) in premature infants with and without patent ductus arteriosus (PDA).
- Conditions
- Premature Infant, Patent Ductus Arteriosus, Hemodynamic Instability
- Trial name
- NCT03277768
- Testing
- Resonance Raman Spectroscopy (RRS)
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Florida
Insufficient Sleep, Hypertension
Sleep Promotion and Pediatric Hypertension
Determine the effectiveness and feasibility of a mobile health sleep extension approach in the pediatric nephrology setting, to increase sleep duration and reduce systolic and diastolic blood pressure.
- Trial name
- NCT06642246
- Testing
- Intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia