Clinical trials: Desaturation
Low IQ, Disorder of Growth and Development
Growth and Intelligence Outcome in Children Who Developed Perioperative Desaturation
The most serious peri-operative respiratory event (PRE) in pediatric anesthesia is desaturation or hypoxemia which could lead to cardiovascular collapse or cardiac arrest.
- Trial name
- NCT01965093
- Testing
- perioperative desaturation, no perioperative desaturation
- Where
- Thailand
- Volunteers
- 104 people
- Sponsor
- Prince of Songkla University
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Desaturation
Effect of High Flow Nasal Cannula on Oxygenation During Urodynamic Study in Pediatric Population
To evaluate the effect of high flow nasal cannula for prevention of hypoxia during deep sedation in pediatric population
- Trial name
- NCT04152733
- Testing
- High flow nasal cannula
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Seoul National University Hospital
Airway Complication of Anesthesia, Peroperative Complication
Comparison of Video Laryngoscopy and Direct Laryngoscopy for Nasotracheal Intubation During Pediatric Dental Surgery
Background and Objective: Airway control is a condition that should be evaluated primarily in anesthesia practice in the pediatric age group.
- Conditions
- Airway Complication of Anesthesia, Peroperative Complication, Intraoperative Hypertension, Tachycardia, Sinus
- Trial name
- Laryngoscopy (NCT04677894)
- Testing
- Laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ordu University
Obstructive Sleep Apnea, Cleft Palate
Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate
The craniofacial abnormalities found in infants and children with cleft palate (CP) lead to increased risk of obstructive sleep apnoea (OSA).
- Trial name
- SLUMBRS2 (NCT04478201)
- Testing
- back sleep positioning, side sleep positioning
- Where
- 11 sites in United Kingdom
- Volunteers
- 244 people
- Sponsor
- Manchester University NHS Foundation Trust
Cerebral Hypoxia, Severe Traumatic Brain Injury
Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit.
Severe traumatic brain injury with a decrease in cerebral oximetry is associated with multiple impaired systemic microcirculations, more morbidities, and a higher mortality rate.
- Trial name
- NCT06306950
- Testing
- Near infrared spectroscopy neuromonitor to prevent cerebral desaturation
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Desaturation of Blood
Early Recognition of Hypoxia in Pediatric Patient Sedation
Early recognition of hypoxia through monitoring in sedation practices in pediatric patients
- Trial name
- NCT04622436
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Neonatal Disorder
Effects of Mother Position in Skin-to-skin Contact Newborn on Oxygen Saturation Levels.
The purpose of this study is to determine if the position of the mother in the first two hours after delivery, while she is in skin to skin contact with your child, influences the oxygen saturation and/or heart rate of the…
- Trial name
- NCT02585492
- Testing
- Head-of-bed elevated 15°, Head-of-bed elevated 45°
- Where
- 7 sites in Spain
- Volunteers
- 1,243 people, healthy volunteers welcome
- Sponsor
- Red Salud Materno Infantil y del Desarrollo
Hypoxemia, Hypoxia
Non Contact Measurement of Vital Signs
The purpose of this study is to test the accuracy of a web cam-based biomedical device developed at UVA (not FDA-approved) that is designed to measure heart rate, respiratory rate, and oxygen saturation without requiring any…
- Trial name
- NCT02287220
- Testing
- Non-Contact Oximetry
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Virginia
Neonatal Respiratory Failure, Tracheal Intubation Morbidity
Providing Oxygen During Intubation in the NICU Trial
Tracheal intubation in the NICU is frequently complicated by severe oxygen desaturation. Apneic oxygenation, a method of applying free flowing oxygen via nasal cannula to apneic patients undergoing intubation, prevents or delays…
- Trial name
- POINT (NCT05451953)
- Testing
- Apneic Oxygenation, Standard of Care
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Identification of Oxygen Desaturation in Patients Admitted Following Adenotonsillectomy'
Sleep apnea has become exceedingly recognized in children. The primary treatment for sleep apnea in children is surgery in the form of adenotonsillectomy.
- Trial name
- NCT06512285
- Testing
- Continuous Pulse Oximetry
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Baylor College of Medicine
Airway Management
Apneic Intubation Critically Ill Children
This study compares the actual standard of care of intubation in Swiss pediatric intensive care units vs the use of apneic oxygenation using either high flow or low flow oxygen to prevent hypoxemia and to prolong apnea time…
- Trial name
- Penguin (NCT04890288)
- Testing
- Interventional randomized controled trial (RCT) comparing two oxygenation methods to reduce desaturation during intubation vs standard of care.
- Where
- 7 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Fatty Acid Metabolism
Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo
We will test the following hypotheses: 1. The activity of the desaturating/elongating enzymes assessed by the in vivo conversion of deuterated a-linolenic and linoleic acids to DHA and AA, respectively, will be related to the…
- Trial name
- NCT00342303
- Where
- 2 sites in Chile
- Volunteers
- 110 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Anaphylaxis, Hypoxia
Virtual Reality-Based Simulation Versus High-Fidelity Simulation for Emergency Management Training in Medical Interns
This study is a two-arm parallel randomized controlled non-inferiority trial designed to compare the educational effectiveness of virtual reality (VR)-based simulation with high-fidelity simulation (HFS) for emergency management…
- Trial name
- NCT07584863
- Testing
- Virtual Reality-Based Emergency Simulation, High-Fidelity Simulation
- Where
- South Korea
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Apnea, Bradycardia
microEEG for Neonatal Apnea, Bradycardia and Desaturation
The study utilizes microEEG (a novel miniaturized, FDA approved EEG device) to prospectively investigate the cerebral electrical activity of infants with Apnea, Bradycardia and Desaturation events.
- Conditions
- Apnea, Bradycardia, Premature Birth, Seizures
- Trial name
- NCT02436616
- Testing
- microEEG
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Bio-Signal Group Corp.
Respiratory Distress Syndrome, Intubation; Difficult or Failed
Nasal Intermittent Positive Pressure Ventilation During Neonatal Intubation
The study aims to determine whether the use of nasal intermittent positive pressure ventilation (NIPPV) during neonatal endotracheal intubation increases the rate of successful intubation without physiological instability during…
- Conditions
- Respiratory Distress Syndrome, Intubation; Difficult or Failed, Newborn Morbidity, Desaturation of Blood
- Trial name
- NCT06549283
- Testing
- Nasal intermittent positive pressure ventilation (NIPPV) via binasal cannula during neonatal intubation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Muğla Sıtkı Koçman University
Congenital Disorders, Cerebral Desaturation
International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery
The goal of this observational study is to determine the incidence of perioperative cerebral desaturation in neonates undergoing surgery for congenital malformations. The main questions it aims to answer are: 1.
- Conditions
- Congenital Disorders, Cerebral Desaturation, Neonatal Surgery
- Trial name
- NCT05673499
- Testing
- NIRS/EEG monitoring
- Where
- 15 sites in United States, Australia and 5 more
- Volunteers
- 900 people
- Sponsor
- Children's Hospital of Philadelphia