Clinical trials: Desaturation
Postoperative Acute Kidney Injury
Intraoperative Renal Desaturation and Postoperative Acute Kidney Injury
The aim of this study is to investigate the changes in renal regional oxygen saturation (rSO2) monitored by near-infrared spectroscopy (NIRS) and its relationship with the occurrence of postoperative AKI.
- Trial name
- NCT04967105
- Testing
- Near-infrared spectroscopy
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Chinese PLA General Hospital
Obstructive Sleep Apnea, Cleft Palate
Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate
The craniofacial abnormalities found in infants and children with cleft palate (CP) lead to increased risk of obstructive sleep apnoea (OSA).
- Trial name
- SLUMBRS2 (NCT04478201)
- Testing
- back sleep positioning, side sleep positioning
- Where
- 11 sites in United Kingdom
- Volunteers
- 244 people
- Sponsor
- Manchester University NHS Foundation Trust
Pulmonary Vascular Disease, Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Exercise Performance on Ambient Air vs. Low-Flow Liquid Oxygen Therapy in Pulmonary Vascular Disease (PVD)
The investigators aim to study the effect of liquid oxygen therapy (4l/min, nasal) )in Swiss residents with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary…
- Conditions
- Pulmonary Vascular Disease, Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Pulmonary Arterial Hypertension (PAH)
- Trial name
- NCT07777445
- Testing
- 6-minute walk distance (6MWD) test on ambient conditions, 6-minute walk distance (6MWD) test with supplemental oxygen (LOX)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Silvia Ulrich Somaini
Hypotension, Hypoxemia
Predictors of Clinically Relevant Hypotension and Hypoxemia During Propofol-Based Diagnostic Gastrointestinal Endoscopy
This prospective observational cohort study will evaluate the incidence and independent predictors of clinically relevant hypotension and hypoxemia during propofol-based diagnostic gastrointestinal endoscopy in adult patients at…
- Trial name
- PRO-GI SAFE (NCT07613073)
- Testing
- Propofol, Diagnostic gastrointestinal endoscopy
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- Bach Mai Hospital
Delirium, Thoracic Surgery
Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients
This study will assess the incidence and risk factors for post-operative delirium in patients undergoing thoracotomy. Specifically, the study will assess if there is any relationship between an intra-operative decrease in brain…
- Trial name
- NCT03165539
- Testing
- Cerebral oxygen saturation monitoring
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Stroke
High Flow Oxygen Therapy and Acute Ischemic Stroke
Hypoxemia is common in acute ischemic stroke and associated with neurological deterioration and mortality. However, the benefit of oxygen therapy is controversial.
- Trial name
- NCT03402594
- Testing
- High flow oxygen, Low flow oxygen
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Intersticial Lung Disease
Can High-Flow Oxygen Therapy Improve Oxygenation During Exercise in ILD Patients?
Objectives: 1.- To compare the level of oxygenation achieved during muscular training with conventional oxygen systems (nasal cannulas) versus nasal High-flow oxygen therapy.
- Trial name
- NCT03287713
- Testing
- oxygen therapy
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Medical Complication
Postoperative Opioid and Respiratory Depression in Opioid Naive and Chronic Opioid Patients
Aim: To describe the duration of desaturation and bradypnea in postoperative opioid-naïve and chronic opioid patients. Patients: 691 patients included from two previous WARD (Wireless Assessment of Respiratory and circulatory…
- Trial name
- NCT06227208
- Testing
- Continuous vital sign monitoring
- Where
- 2 sites in Denmark
- Volunteers
- 691 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cerebral Ischemia
Reversing Cerebral Oxygen Desaturations Greater That 10% of Baseline Values Using NIRS in the ICU
Study objectives: The main objective of this study is to determine the feasibility of implementing measures in the intensive care unit (ICU), based on a physiological algorithm, to reverse decreases in cerebral oxygen saturation…
- Trial name
- NIRS-ICU (NCT01875055)
- Testing
- NIRS and Algorithm, NIRS derived cerebral oximetry
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Manitoba
Sleep Disordered Breathing, Nocturnal Oxygen Desaturation
Determination of the Predictors of Nocturnal Desaturation in Postpartum Women
The primary aim of the study is to evaluate the effect of the method of delivery (vaginal delivery vs. cesarean section) on oxygen saturation in the first postpartum night.
- Conditions
- Sleep Disordered Breathing, Nocturnal Oxygen Desaturation, Upper Airway Edema
- Trial name
- NCT02330055
- Testing
- Forty-five degrees elevated upper body position, non-elevated upper body position, Noninvasive wrist pulse oximeter (WristOx Model 3150)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Massachusetts General Hospital
IPF, Pulmonary Fibrosis
The Effectiveness of Pulmonary Rehabilitation on Saturation in Patients With Idiopathic Pulmonary Fibrosis
The aim of this study is to evaluate the effects of a pulmonary rehabilitation (PR) program on health outcomes and the distance-saturation product in patients with IPF, by comparing two distinct groups: those who experience…
- Trial name
- NCT07031362
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Volunteers
- 50 people
- Sponsor
- Izmir Katip Celebi University
Desaturation of Blood, Obesity
High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal (GI) endoscopy with the patient under deep sedation.
- Conditions
- Desaturation of Blood, Obesity, Colonoscopy, Sleep Apnea
- Trial name
- NCT03148262
- Testing
- The Comfort Flo system, The Salter nasal cannula
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Texas Southwestern Medical Center
Conscious Sedation, Bronchoscopy
Incidence and Nature of Respiratory Impairment in Consecutive Patients Undergoing Bronchoscopy Under Conscious Sedation: A Pilot Study
This study aims to characterize airflow patterns during bronchoscopy under conscious sedation, and determine the incidence of obstructive and central respiratory events.
- Trial name
- NCT03886454
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Tufts Medical Center
Shoulder Arthoscopy, Beach Chair Position
Effect of Compression Stockings on Cerebral Desaturation Events in Obese Patients Undergoing Shoulder Arthroscopy in the Beach Chair
The study compares the effect of thigh high compression stockings on cerebral desaturation events in patients undergoing shoulder arthroscopy in the beach chair position with a BMI greater than or equal to 30.
- Conditions
- Shoulder Arthoscopy, Beach Chair Position, Cerebral Desaturation Events, Obese
- Trial name
- NCT03996668
- Testing
- Thigh High Compression Stockings
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Loyola University
Testing Accuracy, Device Performance
Controlled Oxygen Desaturation Study of the Neonatal Wireless Transmission System
This study aims to test the oxygen saturation component of the newly developed NeWTS monitoring system and compare readings from NeWTS to a traditional wired clinical monitor.
- Trial name
- NeWTS-DS (NCT07813091)
- Testing
- Neonatal Wireless Transmission System
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kathryn Beardsall
Thoracic Surgery, Cognitive Dysfunction
Cerebral Desaturation and Postoperative Dysfunction After Thoracic Surgery
The purpose of this study prospective observational study is to determine cognitive dysfunction incidence after thoracic surgery.
- Trial name
- NCT03805880
- Testing
- cerebral desaturation monitoring and cognitive examination
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
COPD, Exercise
Evolution of Pulsed Oxygen Saturation During Interval Training Compared to Continuous Training in COPD Patients
A problem often observed during exercise training is oxygen desaturation exclusively during exercise in some patients. In the case of exercise-induced desaturation, it may be suggested to train these patients in interval training…
- Conditions
- COPD, Exercise, Pulmonary Rehabilitation, Desaturation of Blood
- Trial name
- NCT05825638
- Testing
- Continuous training session, Interval training session
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Groupe Hospitalier du Havre
Cerebral Desaturation
Observational Study on the Clinical Impact of Desaturation During Liver Surgery
The purpose of this study is to determine the clinical impact of cerebral and systemic desaturation during liver transplantation and resection on post-operative complications.
- Trial name
- NCT01458262
- Testing
- systemic and cerebral oxymetry
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Hypoxia, Pulse Oximetry
SpO2 Difference Between Fingers of the Hand During Sequential Desaturation and Step Resaturation
The aim of the project is to experimentally compare the fingers of the hand in terms of measured concentrations of peripheral blood oxygen saturation (SpO2) in healthy humans during gradual desaturation in the range of 60-100%…
- Conditions
- Hypoxia, Pulse Oximetry, SpO2
- Trial name
- StatDynSpO2 (NCT05681637)
- Testing
- Breathing mixtures of O2 and N2 and monitoring SpO2 on each finger
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork