Clinical trials: Detection
Gonorrhea, Chlamydia
Adolescent Sexually Transmitted Infection Screening in the Emergency Department
Sexually transmitted infections (STIs) are highly prevalent among adolescents. Clinical practices related to screening, diagnosis, treatment, and prevention of STIs among adolescents are suboptimal.
- Trial name
- STI (NCT03715335)
- Testing
- Targeted STI Screening, Universally Offered STI Screening
- Where
- 5 sites in United States
- Volunteers
- 98,413 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
One Eye Blindness, Blind Left Eye
Multiplexing Prism Fitting for Field Expansion of Monocular Vision
The investigators are developing an assistive device, known as multiplexing prism that expands the field of view for individuals with acquired monocular vision (loss of an eye).
- Conditions
- One Eye Blindness, Blind Left Eye, Blind Right Eye
- Trial name
- NCT06027216
- Testing
- Multiplexing Prism
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Infiltration of Peripheral IV Therapy
Optical Detection of Intravenous Infiltration:A Pilot Study
This study will examine the use of the ivWatch Model 400 to monitor PIV sites in pediatric patients. Half the participants will be monitored by the device without infiltration notifications and the other half will be monitored by…
- Trial name
- NCT02553421
- Testing
- ivWatch Model 400
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- ivWatch, LLC
Dravet Syndrome
A Study to Assess the Usability of the Embrace Seizure Detection Watch in Children and Young Adults With Dravet Syndrome
This is an exploratory sub-study to ZX008-1503 [NCT02823145]. Subjects will be fitted with an Embrace seizure detection watch and seizures detected by the watch will be compared to those entered into an electronic seizure diary.
- Trial name
- NCT03299842
- Testing
- ZX008 (Fenfluramine Hydrochloride)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
Colorectal Neoplasms
Third Eye Retroscope Randomized Clinical Evaluation
The Third Eye® Retroscope® is a device that can be inserted through the instrument channel of a standard colonoscope to provide an additional, retrograde (or backward) view that reveals areas behind folds and flexures in the…
- Trial name
- TERRACE (NCT01044732)
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States, Belgium and 3 more
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Schizophrenia, Bipolar Disorder
Early Detection and Intervention for the Prevention of Psychosis
EDIPP is a multisite trial of early identification and intervention to prevent the onset of psychosis in adolescents and young adults, carried out at six sites across the United States.
- Conditions
- Schizophrenia, Bipolar Disorder, Depression, Psychotic Disorders
- Trial name
- EDIPP (NCT00531518)
- Testing
- aripiprazole; fluoxetine; bupropion; sertraline; lamotrigine, Psychoeducational multifamily group treatment, Supported employment and education
- Where
- 6 sites in United States
- Volunteers
- 292 people
- Sponsor
- MaineHealth
Psychosis, First Episode Psychosis
Feasibility of an Early Detection Program for Early Psychosis on a College Campus
The objective of the proposed study is to determine the feasibility of an Early Detection program that aims to: (i) identify college students at clinical high risk (CHR) of psychosis or with first episode psychosis (FEP), and…
- Conditions
- Psychosis, First Episode Psychosis, Clinical High Risk for Psychosis
- Trial name
- NCT03983421
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Musculoskeletal Infection, Acute Hematogenous Osteomyelitis
Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infections
The purpose of this study is to evaluate the use of a blood test: Karius® plasma-based next-generation sequencing test (Karius Test), to see if we can detect and measure the infection causing agent in children with…
- Conditions
- Musculoskeletal Infection, Acute Hematogenous Osteomyelitis, Septic Arthritis, Osteomyelitis
- Trial name
- KDG-002 (NCT03846804)
- Testing
- Karius Test
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Indiana University
Bipolar Disorder, Depression
Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder
This study will develop strategies for early detection and prevention of mood disorders and associated impairment in adolescent children of parents with bipolar disorder.
- Trial name
- NCT00338806
- Testing
- Interpersonal psychotherapy for prevention with adolescents, Educational clinical monitoring
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Lung Cancer
Testing of Computer Aided Detection Software for Riverain Medical Group
This is a clinical trial using retrospective data of two different software devices developed by Riverain Medical Group: Softview and OnGuard 5.0. The two studies will be run concurrently.
- Trial name
- NCT00906789
- Testing
- Software
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Elbow Injury, Elbow Fracture
Pocket Sized Ultrasound (PsUS) and Pediatric Elbow Fractures
The main purpose of this project is to investigate the accuracy of pocket-sized ultrasound (PsUS) in the diagnosis of pediatric elbow fractures.
- Trial name
- NCT05870345
- Testing
- Butterfly IQ
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Varicella
Detection and Characterisation of Varicella Zoster Virus From Dermal Lesions of Chickenpox-infected Patients
This study is conducted in order to collect clinical samples from patients who are diagnosed of having chickenpox infection. The results of this study will provide basic scientific information about chickenpox disease.
- Trial name
- NCT00127608
- Testing
- Collection of clinical samples
- Where
- Czechia
- Volunteers
- 36 people
- Sponsor
- GlaxoSmithKline
Dental Caries
Validation of Near-infrared Light Transillumination for Interproximal Enamel Caries Detection
The aim of this study is to validate a near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany) for interproximal enamel caries detection and compare it with the established diagnostic methods (visual…
- Trial name
- NCT02657538
- Testing
- Non invasive caries treatment, Invasive caries treatment, Near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Cluster Detection
CLUSTER Trial for Outbreak Detection and Response
Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection.
- Trial name
- CLUSTER (NCT04053075)
- Testing
- Routine cluster detection, Enhanced cluster detection
- Where
- 82 sites in United States
- Volunteers
- 2,905,455 people
- Sponsor
- Harvard Pilgrim Health Care
Concussion
Concussion Testing: A Novel Non-invasive Concussion Detection Device
The purpose of this study is to establish and evaluate a distinctive signal for concussion.
- Trial name
- NCT02370914
- Testing
- Nautilus NeuroWaveTM System, SCAT
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
COVID-19, COVID
Clinical Validation of the Aptitude Medical Systems Metrix COVID-19 Test
The Metrix COVID Test will be evaluated for use in Point-of-Care and Non-Laboratory settings in a home testing environment utilizing the clinical study design described herein.
- Trial name
- NCT06744660
- Testing
- Aptitude Medical Systems Metrix COVID Test
- Where
- United States
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- Aptitude Medical Systems
HIV, Sexually Transmitted Diseases
Mobile-Based Application "MyChoices"
This study is testing the acceptability and feasibility of MyChoices, a mobile application (app), to promote HIV testing and pre-exposure prophylaxis (PrEP) uptake among young men who have sex with men (YMSM).
- Conditions
- HIV, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
- Trial name
- NCT03179319
- Testing
- MyChoices
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Patent Ductus Arteriosus
Pocket Echocardiography System (PES) for Detection of PDA in Neonates
This is a single-center, feasibility study involving all neonates admitted to the neonatal intensive care unit with orders for a cardiac echo evaluation. Parents will be approached and provided a description of the study.
- Trial name
- NCT01790750
- Testing
- PES first, then FFES
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Hyperparathyroidism, Primary
18F-Fluorocholine for the Detection of Parathyroid Adenomas
The investigators are studying the ability of F18 labeled fluorocholine PET to localize parathyroid adenomas in patients with hyperparathyroidism prior to surgery.
- Trial name
- NCT03764007
- Testing
- 18F-Fluorocholine, Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Thomas Hope
Prostate Cancer Detection
Zinc/PSA Ratio as a Novel Biomarker for Prostate Cancer Detection
Although Prostate Specific Antigen (PSA) is a useful marker for early detection of the prostate cancer, its specivity is not sufficient.
- Trial name
- NCT02013180
- Where
- Turkey (Türkiye)
- Volunteers
- 480 people
- Sponsor
- Bagcilar Training and Research Hospital