Clinical trials: Developing Countries
Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology
Trial of the Youth Readiness Intervention
The research will first examine data obtained from YRI participants to investigate effects of the group sessions on psychosocial and functioning outcomes in youth.
- Conditions
- Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology, Social Problems/Psychology, Stress, Psychological
- Trial name
- YRI (NCT01684488)
- Testing
- YRI, EducAid educational programming
- Where
- Sierra Leone
- Volunteers
- 443 people
- Sponsor
- Boston College
Nutritional Status
Impact of Exclusive Breast-Feeding in Guinea Bissau
Exclusive breastfeeding is promoted by the World Health Organization (WHO) with the aim of improving infant health. The specific objective of the study was to examine the effect of exclusive breast-feeding on morbidity and…
- Trial name
- NCT00131625
- Testing
- Health education according to WHO recommendations
- Where
- Guinea-Bissau
- Volunteers
- 1,500 people
- Sponsor
- Bandim Health Project
Hemophilia
Musculoskeletal Function in Hemophilia
Hemophilia, which results from deficiency of factor VIII or IX, is a common hereditary X-linked bleeding disorder affecting up to 10/100,000 population. About 60-70% of them have severe disease (factor level <1%).
- Trial name
- NCT00324493
- Where
- 10 sites in Argentina, Brazil and 7 more
- Volunteers
- 250 people
- Sponsor
- Christian Medical College, Vellore, India
Sexual Abstinence, Condom Use
CyberSenga: Internet-based HIV Prevention in Uganda
The investigators propose to design and test an Internet-based HIV prevention program for adolescents in Uganda.
- Trial name
- NCT00906178
- Testing
- CyberSenga
- Where
- Uganda
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Sepsis, Infection
Paediatric Rapid Sepsis Trigger (PRST) Tool
Sepsis is the leading cause of death and disability in children, every hour of delay in treatment is associated with greater organ damage and ultimately death.
- Trial name
- PRST (NCT04304235)
- Testing
- Pediatric Rapid Sepsis Trigger (PRST) tool, Emergency Triage and Treatment (ETAT) guidelines
- Where
- 3 sites in Kenya, Uganda
- Volunteers
- 18,693 people
- Sponsor
- University of British Columbia
Mental Disorder, Depressive Disorder
Reducing Stigma Among Healthcare Providers (RESHAPE-cRCT)
A growing number of trials have demonstrated treatment effectiveness for mental illness by non-specialist providers, such as primary care providers, in low-resource settings.
- Conditions
- Mental Disorder, Depressive Disorder, Anxiety Disorder, Alcohol Use Disorder
- Trial name
- RESHAPE-cRCT (NCT04282915)
- Testing
- Reducing Stigma among Healthcare Providers (RESHAPE), mental health Gap Action Programme
- Where
- Nepal
- Volunteers
- 8,705 people, healthy volunteers welcome
- Sponsor
- George Washington University
Quality Improvement
Evaluation of the Implementation of a Quality Improvement Program Through Morbidity and Mortality Reviews
Morbidity and mortality reviews represent an opportunity to discuss adverse events and healthcare issues. Aim is to report the first experience of implementing a standardized procedure of morbidity and mortality reviews, and…
- Trial name
- NCT05286411
- Where
- Morocco
- Volunteers
- 13 people
- Sponsor
- Moroccan Society of Surgery
Diarrhea, Pneumonia
64N Nutraceutical for the Prevention of Childhood Diarrhea and Pneumonia in Low Resource Settings
The purpose of this study is to compare the occurrence of childhood diarrheal disease and pneumonia in subjects under the age of 5 years in low resource settings who have received prophylactic 64N nutraceutical (64N)as a neonate…
- Trial name
- NCT02231047
- Testing
- 64N Nutraceutical, No 64N Nutraceutical
- Where
- Guatemala
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- H2O Health and Agriculture LLC
Hypothermia
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part III
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604434
- Testing
- Incubator-torso bag, Incubator-no plastic bag
- Where
- Zambia
- Sponsor
- University of Alabama at Birmingham
Infections, Meningococcal, Meningitis, Meningococcic
Fractional Dose Tetravalent A, C, Y, W135 Meningococcal Polysaccharide Vaccine
Hypothesis: Lower doses of each A/C/Y/W135 component of the meningococcal polysaccharide vaccine could confer a similar functional immunogenic response as the dose of 50 μg currently being used, and subsequently be equally…
- Trial name
- NCT00271479
- Testing
- A, C, Y, W135 meningococcal polysaccharide vaccine
- Where
- 2 sites in Norway, Uganda
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Epicentre
Malnutrition, Infection
Effectiveness of Supplementary Feeding During Infection Among Moderately Malnourished Children
The purpose of this study is to determine whether an outpatient-based strategy of short-term, ready to use supplementary food (RUSF) among moderately malnourished children with acute infections achieves greater improvement in…
- Trial name
- MODMAL (NCT00890695)
- Testing
- Ready to use supplementary food (RUSF)
- Where
- 2 sites in Kenya
- Volunteers
- 64 people
- Sponsor
- University of Oxford
HIV Infections, Pregnancy
Nevirapine Plus Zidovudine to Prevent Perinatal HIV in Thailand
The purpose of this study was to assess the efficacy of a single dose of the drug nevirapine (NVP) given to pregnant women at onset of labor and to their infant 48-72 hours after birth in addition to standard oral zidovudine (ZDV…
- Trial name
- NCT00398684
- Testing
- Single dose nevirapine to the mother and to the child
- Where
- Thailand
- Volunteers
- 1,792 people
- Sponsor
- Institut de Recherche pour le Developpement
Hypothermia, Immature Newborn
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part I
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604317
- Testing
- Resuscitation-torso plastic bag, Resuscitation-partial-head plastic bag
- Where
- Zambia
- Volunteers
- 182 people
- Sponsor
- University of Alabama at Birmingham
Surgical Procedures, Operative, Artificial Intelligence (AI)
Artificial Intelligence for Surgical Care in War-Torn Sudan: Feasibility, Barriers, and Ethical Perspectives
This study is designed to examine how artificial intelligence (AI) could be applied to support surgical care in Sudan during the ongoing armed conflict.
- Conditions
- Surgical Procedures, Operative, Artificial Intelligence (AI), War Injury, Wounds and Injuries
- Trial name
- NCT07149012
- Testing
- Artificial Intelligence Awareness and Feasibility Assessment
- Where
- Sudan
- Volunteers
- 185 people
- Sponsor
- Sudan Medical Specialization Board
Major Surgery
Postoperative Complications in Major Surgery
The primary objective of this study is to develop and validate a multivariable risk prediction model for 30-day major postoperative complications and mortality in patients undergoing major surgery across participating…
- Trial name
- SURGCOM (NCT07621198)
- Testing
- Patients with postoperative complications
- Where
- Colombia
- Volunteers
- 364 people
- Sponsor
- Hospital Departamental de Villavicencio
Tuberculosis
Should Low Birth Weight Infants Be Vaccinated With BCG Vaccine at Birth in Developing Countries?
The World Health Organization (WHO) currently recommends BCG vaccination at birth in developing countries. Pre-term infants should be vaccinated when they reach the chronological age of 40 weeks.
- Trial name
- NCT00146302
- Testing
- Bacille Calmette Guerin (BCG)
- Where
- Guinea-Bissau
- Volunteers
- 2,320 people
- Sponsor
- Bandim Health Project
Upper Extremity Defects
Reconstruction of Hand and Upper Extremities Defects by Thin Random Pedicle Abdominal Flaps, Still a Valid Option in Developing Countries: A Cross Sectional Study
Traumatic defects of the soft tissues of the hand and upper extremities are common and may be challenging to the reconstructive surgeon.
- Trial name
- NCT04007497
- Where
- Jordan
- Volunteers
- 34 people
- Sponsor
- University of Jordan
Acute Gastroenteritis
Lactose-free Milk in Infants With Acute Diarrhea in a Developing Country
The purpose of this study is to determine whether lactose-free milk will shorten the diarrhea duration and decrease its severity in formula-fed infants presenting to the Emergency Department (ED) or pediatric clinics with acute…
- Trial name
- NCT02246010
- Testing
- Lactose- free milk
- Where
- Lebanon
- Volunteers
- 6 people
- Sponsor
- American University of Beirut Medical Center
Infant, Newborn, Diseases, Sepsis
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
The purpose of this study is to evaluate whether use of the disinfectant chlorhexidine administered to the birth canal during labour and newborn at delivery can protect a woman and her baby from bacterial infections after birth.
- Conditions
- Infant, Newborn, Diseases, Sepsis, Puerperal Infection
- Trial name
- NCT00136370
- Testing
- Chlorhexidine, Birth canal wipe, sterile water external genital wipe
- Where
- South Africa
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention