Clinical trials: Development, Child
Autism Spectrum Disorder (ASD
EEG As a Genetic Selection Lever in Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a growing public health concern, with genetic causes identified in about 20% of cases. While exome/genome sequencing is powerful, its cost and limited yield call for better patient selection.
- Trial name
- EAGLE (NCT07891065)
- Testing
- Collection of routine care data
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Motor Delay
Effects of Conventional Physical Therapy With and Without Cuevas Medek Exercises in Developmental Delay
There are several etiologies for developmental delay (DD). One of the main causes of developmental delay is cerebral palsy (CP), which has a variety of clinical characteristics brought on by damage to the developing brain.
- Trial name
- NCT06522451
- Testing
- conventional physical therapy, Conventional physical therapy along with cuevas medek exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Developmental Language Disorder, Language Impairment
The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children with Developmental Language Disorder
Of the 12 million children in the USA growing up bilingual, about 1 million experience Developmental Language Disorder (DLD), a disorder in language learning and use.
- Trial name
- NCT06085300
- Testing
- Sentence recast
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Houston
Language Impairment, Autism
Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language Impairment
This study will pilot a newly developed Syntactic-Semantic Visual Configuration Intervention (SSVCI) designed to help Urdu-speaking children with language impairment improve their ability to understand and produce phrases and…
- Conditions
- Language Impairment, Autism, Hearing Impaired Children, Down Syndrome
- Trial name
- SSVC-PILOT (NCT07786545)
- Testing
- Syntactic-Semantic Visual Configuration Intervention (SSVCI)
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Mental Health Issue, Stigma, Social
Implementing an Education- and Health System Task-shifting Approach for Child Mental Health Promotion in Uganda
This study will adapt a school version (mhGAP-IGs) of the World Health Organization´s (WHO) "Mental Health Gap Action Programme Intervention Guide" (mhGAP).
- Conditions
- Mental Health Issue, Stigma, Social, Child Development, Child Abuse
- Trial name
- TREAT (NCT06275672)
- Testing
- Adapted version of the mhGAP-IG
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Autism Spectrum Disorder
Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)
Despite strong consensus that early, specialized intervention for children with Autism Spectrum Disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05425277
- Testing
- Reciprocal Intervention Teaching (RIT), Daily Routines
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism, Autism Spectrum Disorder
Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions
This study is a 12-week randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in youth with Non-Verbal Learning Disorder, High-Functioning Autism Spectrum Disorder, and related…
- Conditions
- Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
- Trial name
- NCT03553875
- Testing
- Memantine Hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Social Communication Disorder
Safety and Efficacy of NDTx-03 in Children and Adolescents With ASD or SCD
The purpose of this study is to evaluate the safety of NDTx-03 used together with treatment as usual (TAU) and to determine whether NDTx-03 plus TAU is more effective than TAU alone in improving social situation recognition and…
- Trial name
- NCT07770867
- Testing
- NDTx-03, TAU
- Where
- 7 sites in South Korea
- Volunteers
- 156 people
- Sponsor
- Neudive Inc.
Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder (ASD)
Comparative Outcomes of VR and In-person Interventions for Preschool-aged Children With Autism Spectrum Disorder
The goal of this clinical trial is to learn whether a virtual reality (VR)-based social skills intervention works as well as an in-person group intervention for improving social skills in preschool children with autism spectrum…
- Trial name
- NCT07594171
- Testing
- Virtual Reality-Based Social Skills Group Intervention, In-Person Social Skills Group Intervention
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Cheng-Kung University Hospital
Normal Development
Therapeutic Effects of Arch Support Insoles on Children
Using double blind, randomized controlled design to study the short-term therapeutic effects of customized arch support insoles on children
- Trial name
- NCT03198299
- Testing
- MEI BIN insoles
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Short Stature, Growth Hormone Deficiency
The IGFBP-3 Stimulation Test: A New Tool for the Diagnosis of Growth Hormone Deficiency in Children.
This project is designed to answer the question: Is there an acute IGFBP-3 response in normal children? Our specific hypothesis states that under the influence of growth hormone secretagogues, intact IGFBP-3 molecule will undergo…
- Trial name
- NCT00235599
- Testing
- IGFBP-3 Stimulation Test
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Unilateral Cerebral Palsy
Wereables for Upper Limb Functionality in Hemiparesis
The project is configured as a national interventional study that aims to determine the effectiveness of an intervention strategy using wearable technology, tailored to improve function (WeFun-wearable), on the spontaneous use of…
- Trial name
- WeFun (NCT06872736)
- Testing
- WeFun-wearable activated, WeFun-wearable desactivated
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidade da Coruña
Music Exposure
Testing the Effects of Music on Short and Long Term Psychological Outcomes and Step Counts in Children
The goal of this clinical trial is to investigate whether asynchronous music can improve outcomes of an 8-week long sport based youth development program.
- Trial name
- NCT07358871
- Testing
- Music in Sport Based Youth Development, No Music Exposure
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autistic Spectrum Disorder, Vestibular Disorder
the Effect of Vestibular Rehabilitation in Autistic Children
This study was conducted to clarify the effect of vestibular education for autistic children on "sensory profile" and "postrotary nystagmus".
- Conditions
- Autistic Spectrum Disorder, Vestibular Disorder, Sensory Integration Disorder
- Trial name
- NCT03957044
- Testing
- The education of sensory integration with vestibular education
- Volunteers
- 22 people
- Sponsor
- Istinye University
Chronic Lung Disease
Study to Assess the Immune Reactivity of the Liquid and Lyophilized Formulations of Palivizumab (MEDI-493, Synagis)
The purpose of this study is to measure the rate of anti-palivizumab antibodies (also referred to as immune reactivity or immunogenicity) in subjects receiving either the liquid or lyophilized formulation of palivizumab.
- Trial name
- NCT00233064
- Testing
- Lyophilized Palivizumab, Liquid Palivizumab
- Where
- 54 sites in United States
- Volunteers
- 417 people
- Sponsor
- MedImmune LLC
Autism
The Effects of Video Modeling of Audiological Testing on Pediatric Patient Compliance
The purpose of the current study is to determine if pre-exposure through video modeling will enhance testing compliance in a population of children who are receiving a diagnostic evaluation for Autism.
- Trial name
- NCT03002363
- Testing
- Video Modeling Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism Spectrum Disorder
Therapeutic Impacts of Theta Burst Stimulation Over Bilateral Posterior Superior Temporal Sulcus in Autism Spectrum Disorder
The investigator would like to investigate the impact of intermittent theta burst stimulation over bilateral posterior superior temporal sulcus in autism spectrum disorder
- Trial name
- NCT05578209
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Developmental Disability
Occupational Performance Coaching With Parents of Young Children With Developmental Disability
Participation in community activities allows children to meet friends, learns new skills, fosters independence, and paves the foundation for lifelong health.
- Trial name
- NCT04796909
- Testing
- Occupational Performance coaching, Parent consultation
- Where
- 3 sites in Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder
Autologous BMMNCs Combined With Educational Intervention for ASD
The purpose of this study is to evaluate the safety and effectiveness of autologous bone marrow mononuclear cell infusion combined with educational intervention for children with autism spectrum disorder (ASD).
- Trial name
- NCT05307536
- Testing
- Autologous BMMNCs transplantation and educational intervention, Educational intervention
- Where
- Vietnam
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Autism Spectrum Disorder
Hyperthermia and the Amelioration of Autism Symptoms
The febrile hypothesis of Autism Spectrum Disorder (ASD) stems from the observation that clinical symptoms improve during fever.
- Trial name
- NCT01784744
- Testing
- Hydroworx Pool at 98 degrees Fahrenheit, Hydroworx Pool at 102 degrees Fahrenheit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Montefiore Medical Center
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