Clinical trials: Development, Child
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Asperger Syndrome, Autism
Evaluation of the French Version of Screening Questionnaires for Autism and Asperger Syndrome: AQ, EQ and SQ
Autism is considered as an invading disorder of the development. Asperger Syndrome (AS) is a particular form of autism and is difficult to diagnose.
- Trial name
- NCT00505830
- Testing
- questionnaires
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Groupe Francais d'Epidemiologie Psychiatrique
Autism Spectrum Disorder
Prevalence and Healthcare Consumption of ASD Patients Using French Medico-administrative Data
Autism Spectrum Disorder (ASD) is one of the neurodevelopmental disorders described in the DSM5 (American Psychiatric Association, 2013).
- Trial name
- ECO-TSA (NCT06409728)
- Where
- 2 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Developmental Disability, Child Autism
The Effect of Group Exercise in Children With Special Needs
Thirty children with special needs were included in the study. Participants engaged in group exercises twice a week for four weeks, including warm-up and cool-down periods, with the goal of improving balance.
- Trial name
- NCT06353867
- Testing
- Group Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Gedik University
Autism Spectrum Disorder
Computer-based Social Skills Training for Autism Spectrum Disorder
The primary objective of this study is to evaluate changes in subject performance on social skills assessments after engaging in a gaze-controlled video game that leverages ABA principles of learning, in comparison to an…
- Trial name
- NCT03672344
- Testing
- Lookware TM, Lookware TM Control Module
- Where
- 11 sites in United States
- Volunteers
- 54 people
- Sponsor
- BioStream Technologies, LLC
Dravet Syndrome
Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies
This is a multicenter, prospective, 2-year observational study in infants and children with developmental and epileptic encephalopathies (DEEs). The DEE currently being investigated is SCN1A-positive Dravet Syndrome.
- Trial name
- ENVISION (NCT04537832)
- Testing
- No Intervention
- Where
- 16 sites in United States, Australia and 2 more
- Volunteers
- 58 people
- Sponsor
- Encoded Therapeutics
Central Auditory Processing Disorder
Virtual Reality Game to Enhance Auditory Processing in Children With Cochlear Implants
This study aimed to design and evaluate the effectiveness of a virtual reality-based restaurant simulation game to improve central auditory processing skills in children with bilateral cochlear implants.
- Trial name
- NCT06788184
- Testing
- Virtual Reality (VR) Game for Auditory Processing, Traditional Auditory Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul Aydın University
Healthy, Family Research
Pediatric Parenting Support in Flint
Public health disasters have disproportionate impacts on low income communities, through pathways that add to those of poverty and associated stressors, and act over extended periods.
- Trial name
- NCT03945552
- Testing
- Video Interaction Project
- Where
- 2 sites in United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Craniosynostosis, Bleeding
Tranexamic Acid for Craniofacial Surgery
This is a randomized, blinded, prospective study that will investigate the potential benefit of tranexamic acid to reduce the intraoperative bleeding and blood transfusions in pediatric patients undergoing craniofacial surgeries.
- Trial name
- NCT00722436
- Testing
- Tranexamic acid, saline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics (NeuroToP - a COPANA Follow up)
Fundamental aspects of both neurological and reproductive function are established in fetal life, and there is a present increased awareness of the potential effects of fetal exposures on neurodevelopmental and reproductive…
- Conditions
- Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction, Developmental Disability, Adhd
- Trial name
- NeuroToP (NCT07316387)
- Where
- Denmark
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autistic Disorder
Treatment of Autism in Children and Adolescents
This study is designed to determine the effectiveness of risperidone, a drug treatment for the interfering symptoms of Autistic Disorder in children and adolescents between the ages of 5 and 17.
- Trial name
- NCT00005014
- Testing
- Risperidone
- Where
- 5 sites in United States
- Volunteers
- 101 people
- Sponsor
- National Institute of Mental Health (NIMH)
HIV, HIV-uninfected Children
A Cross Sectional Evaluation of the Development in Children Age 4 to 7 Infected or Exposed to HIV From the ANRS 12140 Cohort (Pediacam)
This study aims to perform a comprehensive neuro-cognitive evaluation of the 4-7 year old children from the Pediacam cohort (ANRS 12140 /12225, NCT02043418).
- Conditions
- HIV, HIV-uninfected Children, Children Exposed to HIV
- Trial name
- PediacamDEV (NCT02570334)
- Testing
- HIV-infected children initiated antiretroviral treatment within the first 7 months of life
- Where
- 3 sites in Cameroon
- Volunteers
- 400 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Developmental Disability
Developing and Examine the Efficacy of the Family-Centered Multi-Sensory Environment Intervention on Parent's Empowerment and Children's Engagement (MSE-PEACE) in Children With Developmental Disabilities and Their Parents: A Mixed Methods Study
The goal of this clinical trial is to learn whether a family-centered multi-sensory environment (MSE-PEACE) can help children with developmental disabilities and support their parents.
- Trial name
- MSE-PEACE (NCT07118293)
- Testing
- MSE-PEACE
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Very Low Birth Weight Infants
Efficacy of Multiple Strain Probiotics Reduces the Neurobehavioral Disorder in Premature Very Low Birth Weight Infants
The management protocols, clinical practices, equipment, infrastructure, and key personnel in NICU are unchanged during the study period.
- Trial name
- NCT03858816
- Testing
- Mixture probiotics
- Where
- Taiwan
- Sponsor
- China Medical University Hospital
Post Partum Depression
Adaptation and Pilot Testing of Web and Mobile Interface for the VID-KIDS Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stress (depression, addiction, intimate partner violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of…
- Trial name
- VID-KIDS (NCT04818047)
- Testing
- VID-KIDS Intervention Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Malnutrition, Child, Development, Child
Grandi Byen: Test of an Integrated Parenting and Nutrition Intervention
The premise of this trial is that a combined nutrition (eggs) and parenting behavior intervention (responsive parenting combined with the reinforcement of animal source foods and improved WASH) will synergistically result in…
- Conditions
- Malnutrition, Child, Development, Child, Parenting
- Trial name
- NCT04785352
- Testing
- Nutrition Intervention, Grandi Byen
- Where
- Haiti
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Child Development
Enhancing And Supporting Early Development to Better Children's Lives (EASEL) Trial
In The Lancet's series on advancing early childhood development, provision of high-quality early childhood care and education was listed as one of the main factors that can maximize children's potential to succeed in later life…
- Trial name
- EASEL (NCT05445947)
- Testing
- The EASEL (Enhancing And Supporting Early Development to Better Children's Lives) Approach
- Where
- 4 sites in Singapore
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Growth Hormone Deficiency
Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone Deficiency
To evaluate the safety and efficacy of PEG Somatropin Injection (Jintrolong®) in the treatment of short stature due to endogenous growth hormone deficiency (GHD) in the broad of population of children.
- Trial name
- NCT02908958
- Testing
- PEG-somatropin
- Where
- 22 sites in China
- Volunteers
- 900 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Developmental Delay, Disruptive Behavior
Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program
The Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program is a study funded by the National Institutes of Health to explore behavior and developmental problems among young children aging out…
- Trial name
- ACCESS (NCT03260816)
- Testing
- Internet-delivered Parent-Child Interaction Therapy (I-PCIT), Referrals as Usual (RAU)
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Florida International University
Lifestyle Modification
KeySteps@JC Phase Two Study
This proposed 'KeySteps Phase Two Study' is a 5-year study, which aims to investigate the effectiveness and sustainability of a Community Child Health Model with different services related to healthy lifestyle programmes and…
- Trial name
- NCT06113042
- Testing
- Health talks, learning packs, Lifestyle modification programme, School healthy environment evaluation
- Where
- Hong Kong
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
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