Clinical trials: Development, Child
Autism Spectrum Disorder, Autism
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost…
- Conditions
- Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders
- Trial name
- LUNA-A (NCT06537128)
- Testing
- LUNA-Adolescent, Treatment as Usual
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder
Vestibulo-Ocular Reflex for Balance and Stimming in Autism Spectrum Disorder
Autism spectrum disorder is a neurodevelopmental disorder that encompasses a number of disorders specifically affecting social skills, Communication and present with Rapid repetitive behaviors.
- Trial name
- NCT06340139
- Testing
- conventional treatment, experimental treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
A Placebo-controlled Trial of Folinic Acid in Children With ASD
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and the presence of restricted or repetitive behaviors.
- Trial name
- AFAT (NCT07642661)
- Testing
- Folinic Acid
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Prof. Adi Aran
Spinal Muscular Atrophy, Assessment, Self
Development of a Space Exploration Assessment for Children With Spinal Muscular Atrophy
The aim of this randomized study is to develop a new motor assessment of space exploration in a 2D environment with upper limbs for children with spinal muscular atrophy 1 and 2 from 3 until 16 years old.
- Trial name
- ExplorASI (NCT03223051)
- Testing
- Motor assessment
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Tuberculosis, Diagnostics
Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)
Every year there are an estimated 230,000 childhood deaths from TB. There is an urgent need for novel tests for TB diagnosis in children under 15 years.
- Conditions
- Tuberculosis, Diagnostics, Global Health
- Trial name
- NCT05989802
- Testing
- Oral swab molecular testing, Automated Cough Sound Analysis, Automated Lung Sound Analysis
- Where
- 3 sites in Mozambique, South Africa and 1 more
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With Autism Spectrum Disorder
Study ITI-007-035 is a Phase 1b, multicenter, open-label study to evaluate the safety, tolerability, and PK of lumateperone for pediatric patients with Autism Spectrum Disorder.
- Trial name
- NCT06557902
- Testing
- Lumateperone 10.5 mg capsule, Lumateperone 21 mg capsule, Lumateperone 5 mg ODT
- Where
- 7 sites in United States
- Volunteers
- 33 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Autism Spectrum Disorder
Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)
Despite strong consensus that early, specialized intervention for children with Autism Spectrum Disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05425277
- Testing
- Reciprocal Intervention Teaching (RIT), Daily Routines
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Washington
Child Development
The Effect of a New Infant Formula on Growth and Cognition in Healthy Term Infants
This study is a multicenter, double-blind, randomized, controlled, parallel-designed, prospective trial and is intended to evaluate the nutritive effects of two staged study formulas on growth and cognitive outcomes.
- Trial name
- NCT04508257
- Testing
- Oral feeding of Investigational Formula (Stage 1&2), Oral feeding of Control formula (Stage 1&2), Breast feeding
- Where
- 3 sites in China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Autism
Joint Attention Intervention and Young Children With Autism
The purpose of this study is to investigate the effectiveness of an intervention aimed to increase joint attention in 2-4 year old children with autism. The study will be conducted in mainstream preschools in Norway.
- Trial name
- NCT00378157
- Testing
- Joint attention intervention
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Ullevaal University Hospital
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders
This study will examine the effectiveness of riluzole for treating Obsessive-Compulsive Disorder in Youth, Including those with Autism Spectrum Disorders.
- Conditions
- Obsessive-Compulsive Disorder, Autism Spectrum Disorder, Autism, Asperger Disorder
- Trial name
- NCT00251303
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Mental Health (NIMH)
Executive Function, School Readiness
Playful Physical Activity Program and Executive Function in Preschool Children
This randomized controlled trial evaluates the effects of an 8-week cognitively enriched playful physical activity program on executive functions and school readiness in preschool children.
- Trial name
- NCT07488286
- Testing
- Playful Physical Activities, Standard Physical Education Group
- Where
- Tunisia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Monira Aldhahi
Autism, Intellectual Disability
Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Trial name
- NCT02914951
- Testing
- Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Developmental Disabilities, Sleep Disorders
Use of an Educational Story to Prepare Children With Developmental Disabilities for Sleep Study
The investigators hypothesize that use of an educational story with pictures illustrating overnight sleep study procedure (also called polysomnography or PSG)accompanied by simple narrative will be a cost-effective, readily…
- Conditions
- Developmental Disabilities, Sleep Disorders, Polysomnography, Preparation for Medical Procedure
- Trial name
- NCT02132273
- Testing
- Educational Story
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jennifer Accardo
Autism Spectrum Disorder (ASD)
Double-blind Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders
The main objective of this exploratory 8 week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT01395953
- Testing
- Buspirone
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Down Syndrome
Effects of Play Based Therapy on Attention Level of Children With Down Syndrome
The aim of the study is to examine the attention level of children with down syndrome receiving play based therapy as compared to children receiving child centered play therapy.
- Trial name
- NCT06893666
- Testing
- Play based therapy, Child centered play therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Preliminary Effects of the CO-OP Approach in Children With Autism Spectrum Disorder
Autism spectrum disorder may affect children's participation in daily occupations through difficulties related to motor planning, problem-solving, attention, behavioral regulation, and sensory processing.
- Trial name
- NCT07717853
- Testing
- Cognitive Orientation to Daily Occupational Performance Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Atlas University
Bottle Feeding, Dental Caries in Children
Controlling ECC and Terminating Bottle-feeding Habits Among Toddlers Using a Modified Oral Care Package
This study will evaluate the effectiveness of oral health promotion in the prevention of ECC (early childhood caries) in bottle-fed children.
- Trial name
- NCT04440137
- Testing
- Bottle-feeding cessation program
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Autism Spectrum Disorder
Group Based Parent Training for Children With Autism and Disruptive Behaviors
The goal of the study is to providing parents of children diagnosed with autism spectrum disorders (ASD) and disruptive behaviors essential skills to manage their children's behaviors using an evidence based parent training…
- Trial name
- NCT04097457
- Testing
- "Parent training for disruptive behaviors" manual (Bearss, Johnson, Handen, Butter, Lecavalier, Smith & Scahill, 2018)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hebrew University of Jerusalem
Silver Russell Syndrome, Prader-Willi Syndrome
Aromatase Inhibitor in Bone Maturation, Children With Silver Russell or Prader-Willi Syndrome
There is currently no drug with pediatric marketing authorization capable of limiting the advance in bone maturation of children with aggressive adrenarche.
- Trial name
- ANASILPRA (NCT01520467)
- Testing
- Anastrozole
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Genetic Diseases, Metabolic Diseases
Genetic and Metabolic Disease in Children
This is a prospective, non-randomized, non-blinded observational study. The overarching goal is to discover new disease-associated genes in children, while establishing a specific focus on disorders where molecular…
- Trial name
- NCT02650622
- Testing
- Skin Biopsy
- Where
- United States
- Volunteers
- 1,550 people
- Sponsor
- University of Texas Southwestern Medical Center
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