Clinical trials: Development
Developmental Language Disorder and Language Impairment, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder and Language Impairment, Specific Language Impairment, Language Development
- Trial name
- NCT07048392
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Skill Development of Staff, Clinical Practice
Peripheral Venous Access Management by Radiologic Technologists in Radiodiagnostic Procedure
The goal of this interventional study is to evaluate the impact of a structured training program on the ability of Radiologic Technologists (RTs) to safely and effectively perform peripheral venous access (PVA) placement for…
- Conditions
- Skill Development of Staff, Clinical Practice, Patient Satisfaction
- Trial name
- TSRM_01 (NCT07411430)
- Testing
- Structured Peripheral Venous Access Training Program
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Parent-Child Relations, Parenting
CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood
Disparities in health begin in early childhood. Early life experiences influence brain development and have significant implications on future health and developmental outcomes.
- Conditions
- Parent-Child Relations, Parenting, Child Development, Child Behavior
- Trial name
- NCT03641092
- Testing
- CenteringParenting Intervention, Routine Well Child Care
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Child Development, Child Language
The Pittsburgh Study Early Childhood
The Early Childhood Collaborative of The Pittsburgh Study is a community-partnered, county-wide implementation of programs for children and families from birth through formal school entry to address real-world challenges that…
- Conditions
- Child Development, Child Language, Child Behavior Problem, Parenting
- Trial name
- TPS-ECC (NCT05444205)
- Testing
- Text4Baby or Bright by Text Referral, Nurture Program Warm Referral, Video Interaction Project
- Where
- 5 sites in United States
- Volunteers
- 2,546 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Socioemotional Development, Physical Activity
Newenkantun: a Play-based Program to Promote Socioemotional Learning in Early Childhood Education in Chile.
What is this study about? This study will test a program called "Newenkantun" (which refers to a hand-strength game in Mapuche culture) designed to help young children develop important social and emotional skills through play…
- Conditions
- Socioemotional Development, Physical Activity, Sleep, Motor Skills
- Trial name
- Newenkantun (NCT07871929)
- Testing
- Teacher Professional Development, Parent/guardian support, Play-Based Activities and Environmental Modifications
- Where
- 2 sites in Chile
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Child Development
Effects of Five Stones Pebble Game on In-Hand Manipulation and Hand Writing Skills of School-going Children
This randomized controlled trial will be conducted on 26 school-going children (aged 8-12 years) from The City School and Classic School System, randomly assigned to a traditional play group or an unstructured gameplay group…
- Trial name
- NCT07872293
- Testing
- Five Stones Pebble Game, Unstructured Play Group
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Preterm Birth, Very Preterm Infant
NICU-to-Home Dyadic Support for Very Preterm Infants and Families
This feasibility study will evaluate delivery of the Supporting Play Exploration and Early Development Intervention after neonatal intensive care unit discharge for very preterm infants and their families.
- Conditions
- Preterm Birth, Very Preterm Infant, Infant Development, Neonatal Intensive Care Unit
- Trial name
- MN-SPEEDI (NCT07820462)
- Testing
- Homebased SPEEDI, Telehealth SPEEDI
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Reproductive Physiological Processes, Pediatrics
Reproductive Axis Maturation in the Early Post-Menarchal Years
Background: Most adult women with irregular periods of unknown cause report symptoms dating back to early adolescence. This study aims to learn how girls' periods change in the 2 years after their first period.
- Conditions
- Reproductive Physiological Processes, Pediatrics, Adolescent Health, Adolescent Development
- Trial name
- NCT03986021
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Autism Disorder, Language Development Disorders
Rural Autistic Individuals - Supporting Expression
This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are…
- Conditions
- Autism Disorder, Language Development Disorders, ADHD, Typical Development
- Trial name
- RAISE (NCT07054866)
- Testing
- Speech-Gesture combinations
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montana State University
Vitamin D 25-Hydroxylase Deficiency, Undernutrition
Impact of Trout Fish, Cow Milk With Egg, Vitamin D Supplementation, and Dietary Education on Vitamin D Status, Undernutrition, and Neurocognitive Outcomes Among School Children in Pakistan: An Open-label Individually Randomized Controlled Trial
Vitamin D deficiency and undernutrition are major public health concerns globally, particularly among children in low-resource and high-altitude settings.
- Conditions
- Vitamin D 25-Hydroxylase Deficiency, Undernutrition, Neurocognitive Development
- Trial name
- NCT07864662
- Testing
- Vitamin D supplement 4000 IU weekly, 200 grams of cooked trout fish, 250 milliliters of whole cow milk + whole egg
- Where
- Pakistan
- Volunteers
- 304 people
- Sponsor
- Aga Khan University
Motor Delay, Infant Development
Wearable Sensor Toolkit for Infant Motor Development
The purpose of this study is to develop and test a fully automated, wireless sensor-based toolkit for infants that can capture early indicators (0-3 months) of motor deficits during activities of daily life and track motor…
- Conditions
- Motor Delay, Infant Development, Motor Development of Premature Infants, Motor Coordination or Function; Developmental Disorder
- Trial name
- NCT07866495
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Heat Stress, Physiological Stress
Efficacy of Electric Fans in Children During Heat Waves
Extreme heat exposure is an escalating global public health concern, with climate change driving increases in the frequency, duration, and intensity of heat events.
- Conditions
- Heat Stress, Physiological Stress, Child Development
- Trial name
- NCT07864103
- Testing
- Simulated exposure to indoor overheating without fans, Simulated exposure to indoor overheating with fans
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Disorders of Sex Development (DSD), Pediatric and Adolescent Cancers of the Genital Tract
Data Collection Study of Pediatric and Adolescent Gynecology Conditions
Background: Gynecologic conditions are those that are related to the reproductive system. They can be reproductive gland disorders or reproductive system tumors. They can also be inborn anomalies of the reproductive tract.
- Conditions
- Disorders of Sex Development (DSD), Pediatric and Adolescent Cancers of the Genital Tract, Reproductive Endocrine Conditions in Puberty, Structural Gynecologic Conditions Including Vulvar and Vaginal Conditions
- Trial name
- NCT04717349
- Where
- United States
- Volunteers
- 11,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Motor Development
Motor Development of Normal Children
The goal of this type of study: observational study is to compare motor development between urban and rural regions in pre-school age children.
- Trial name
- NCT05948176
- Testing
- The Bruininks-Oseretsky Test of Motor Proficiency, Second Edition
- Where
- 2 sites in Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cairo University
Developmental Language Disorder
The Effect of Prior Learning on Treatment of Morpheme Errors
This is a small-scale treatment study designed to determine which teaching methods result in the best learning. Treatment focuses on helping children with a developmental language disorder learn parts of grammar.
- Trial name
- NCT05953077
- Testing
- Conversational recasting
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arizona
Healthy Volunteers, Child Development
Play-Based Motor Training in Children Aged 7-10 Years
This randomized controlled study evaluated the effects of an 8-week structured play-based motor training program on motor competence in children (boys and girls) aged 7-10 years.
- Trial name
- PBMT-DC (NCT07771959)
- Testing
- Structured Play-Based Motor Training Program, Usual Physical Education
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Child Development
The Influence of Maternal Age, Employment Status, and Parenthood Status on Children's Cognitive Development
Research and theory tend to agree when suggesting that certain activities done by mothers have both immediate and delayed consequences for children's mental development in the first years of life.
- Trial name
- NCT00361829
- Where
- 4 sites in United States, Brazil and 2 more
- Volunteers
- 2,355 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Guideline Development
Wording Approaches to Convey the Strength of Recommendations in Health Guidelines
Recommendations from health organizations rest on a scale. On this scale, some recommendations can be "stronger" than others. This "strength" should be easily understood by everyone, including members in the public and healthcare…
- Trial name
- (SOR) (NCT07854548)
- Testing
- GRADE approach ("recommends" and "suggest"), New approach ("strongly recommends" and "conditionally recommends"), Alternate approach ("should" and "may")
- Where
- Canada
- Volunteers
- 741 people, healthy volunteers welcome
- Sponsor
- McMaster University
Turner Syndrome, Short Stature Homeobox Gene Mutation
Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders
This basket trial will enroll prepubertal children and adolescents with clinically diagnosed and genetically confirmed (if applicable) TS, SHOX-D, SGA, or ISS between ages of ≥2 and <18 years with open growth plates.
- Conditions
- Turner Syndrome, Short Stature Homeobox Gene Mutation, Idiopathic Short Stature, Small for Gestational Age at Delivery
- Trial name
- NCT07221851
- Testing
- Lonapegsomatropin [SKYTROFA®], Somatropin Pen Injector
- Where
- 51 sites in United States, France and 5 more
- Volunteers
- 186 people
- Sponsor
- Ascendis Pharma A/S
Child Development
Effects of Animal Fun Program in Children With DCD.
This randomized clinical trial investigates the effects of animal fun program on motor skills in children with developmental coordination disorder.
- Trial name
- NCT07244055
- Testing
- animal fun program, control group
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University