Clinical trials: Development Delay
Refractive Errors, Amblyopia
Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines
Pediatric eye patients receive infrared photoscreener screening and skiascopy as a part of routine examination to compare ability to detect amblyopia risk factors.
- Conditions
- Refractive Errors, Amblyopia, Strabismus, Development Delay
- Trial name
- 2WINbus (NCT03668067)
- Testing
- 2WIN photoscreener
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Alaska Blind Child Discovery
Gross Motor Development Delay
The Effects of Playful Pathways
The purpose of this study is to evaluate infants ages 0-6 months of age before and after an 8 week developmental and educational "caregiver and baby" interactive program as well as 3 month following the conclusion of the program.
- Trial name
- NCT06139549
- Testing
- Gross motor development group session
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Down Syndrome, Gross Motor Development Delay
Investigating Trunk Control in Young Children With Down Syndrome
Overall, the purpose of this dissertation research is to investigate trunk control in young children with DS. This will be done in three studies: 1.
- Trial name
- NCT03544840
- Testing
- Physical Therapy Home Program
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Texas Woman's University
Development Delay
Effects of Adapted Physical Activities on Visual Motor Integration in Children With Developmental Delay
Developmental delay occurs when a child does not achieve developmental milestones in comparison to peers of the same age range. Children and adolescents with developmental delay often experience participation restrictions.
- Trial name
- NCT05969808
- Testing
- baseline therapy and conventional therapy, baseline treatment and adaptive physical activity
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Obesity, Genetic Disorder
Brain-Derived Neurotrophic Factor in Obesity and Brain Function
Background: Prader-Willi syndrome (PWS) and MC4R genetic mutations are two conditions that can cause problems with appetite regulation. People with PWS often have behavior and thinking problems.
- Conditions
- Obesity, Genetic Disorder, Mental Retardation, Developmental Delay
- Trial name
- NCT01517048
- Where
- 2 sites in United States, Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Speech, Language Developmental Delay From Hearing Loss
Comparative Effects of Play Based Therapy and Functional Communication Training in Speech-language Delayed Children
The purpose of this study is to compare the play based therapy and functional communication training in speech-language delayed children 2-6 years old.
- Trial name
- NCT05749315
- Testing
- Play Based Therapy, Functional Communication Training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sehat Medical Complex
Developmental Delay
Early Intervention in Children at Risk of Developmental Delay
Although it is stated in the literature that development should be considered as a whole and sensory, cognitive and motor outcomes are interrelated, it is seen that interventions for sensory and cognitive skills are not included…
- Trial name
- NCT06052410
- Testing
- Early Intervention, Home Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Developmental Disabilities
The Investigation of Children With Developmental Delay and Children's Rehabilitation Common Case
Children with developmental disabilities and children's rehabilitation common case investigation: Long-term follow-up study.
- Trial name
- NCT02686931
- Where
- Taiwan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Intellectual Disability, Cerebral Palsy
Oral Health Promotion Among Preschool Children With Special Needs
Establishing good oral health-related habit is challenging among younger children, especially for preschool children with special needs, as they have physical, mental, sensory, behavioural, emotional, and chronic medical…
- Conditions
- Intellectual Disability, Cerebral Palsy, Developmental Disorders, Developmental Delay
- Trial name
- NCT03522337
- Testing
- Visual pedagogy (social stories), Conventional leaflets
- Where
- China
- Volunteers
- 306 people
- Sponsor
- The University of Hong Kong
Groin Injury
Comparison of the Effect of Copenhagen Adduction Exercises Performed at Different Load-intensity
The aim of our study is to compare the effects of the Copenhagen adduction exercise, performed at different loading intensities, on hip muscle strength development, performance, flexibility, and delayed onset muscle soreness.
- Trial name
- NCT06104722
- Testing
- High-intensity Copenhagen adduction exercise, Low-intensity Copenhagen adduction exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorder, Moderate Language Delay
Direct Instruction Language for Learning in Autism Spectrum Disorder
The purpose of this study is to test whether Direct Instruction - Language for Learning (DI-LL) is an effective way to teach language skills to children with autism spectrum disorder (ASD) and moderate language delay.
- Trial name
- DILLASD (NCT02483910)
- Testing
- Direct Instruction-Language for Learning (DI-LL) via telehealth (e.g., Zoom or WebEx), Standard of care delivered via telehealth (e.g., Zoom or WebEx)
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Emory University
Gestational Diabetes Mellitus in Pregnancy, Cognitive Impairment
Gestational Diabetes Mother-infant Cohort
The bi-directional dynamic cohort study is to learn about the effects of prenatal exposure to high blood glucose levels and postnatal nurturing environment factors on delayed language development in children.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Cognitive Impairment, Cohort Study
- Trial name
- NCT06021691
- Testing
- Acquired nurturing environment
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gansu Provincial Maternal and Child Health Care Hospital
Intellectual Disabilities, Speech Delay
Pivotal Response Treatment for Individuals With Intellectual Disabilities
The investigators will assess the efficacy of Pivotal Response Treatment (PRT) in the treatment of communication deficits in children with intellectual disabilities.
- Conditions
- Intellectual Disabilities, Speech Delay, Language Disorder
- Trial name
- NCT01988623
- Testing
- Pivotal Response Treatment (PRT)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Stanford University
Developmental Delay, Preschool Children
Effects of Fairytales on Preschool Children With Attention Deficit Hyperactivity Disorder
Under traditional rehabilitation programs, investigate the additional effects of individualized fairytales on preschool children with Attention Deficit Hyperactivity Disorder with developmental delays.
- Conditions
- Developmental Delay, Preschool Children, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT05502536
- Testing
- Traditional rehabilitation programs with Individualized fairytales class
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University
Developmental Disabilities, Language Development Disorders
Preventing Learning Problems in Young Children: A Public Health and Physician-Based Outreach
This study will evaluate a program to prevent learning problems in children. The program is an inexpensive public health outreach program designed for families living in poverty and is administered through pediatricians' offices…
- Trial name
- NCT00110292
- Testing
- Age-specific parenting newsletters and developmental toys, Parent-completed Ages & Stages Questionnaires, Clinic-based distribution of children's books
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Intellectual Disability, Developmental Delay
Establishing the Clinical Utility of First StepDx PLUS and NextStepDx PLUS Study
The study uses a randomized controlled study design of pediatric neurologists and developmental pediatricians and front-line (primary care) pediatricians to determine if use of FirstStepDx PLUS and Next StepDx PLUS are associated…
- Trial name
- NCT02414438
- Testing
- FirstStepDX PLUS and NextStepDX PLUS Webinar, FirstStepDX PLUS and NextStepDX PLUS Test Results
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Developmental Language Disorder, Language Delay
Using Neuroimaging and Behavioral Assessments to Understand Late Talking
Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder.
- Conditions
- Developmental Language Disorder, Language Delay, Language Development
- Trial name
- NCT06156865
- Testing
- Intervention to address late talking
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Motor Delay, Neurodevelopmental Disorders
Wearable Sensors and Video Recordings to Monitor Motor Development
The objective of this study is to develop an automated, precise, quantitative assay for detecting atypical motor behavior and development in infants using data from wearable sensors and video recordings.
- Conditions
- Motor Delay, Neurodevelopmental Disorders, Developmental Disability
- Trial name
- NCT03770832
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Shirley Ryan AbilityLab
Angelman Syndrome, Nervous System Diseases
Dietary Supplements for the Treatment of Angelman Syndrome
Angelman syndrome (AS) is a complex genetic disorder that affects the nervous system. The purpose of this study is to determine the effectiveness of certain dietary supplements in treating the symptoms of AS.
- Trial name
- NCT00348933
- Testing
- Betaine, Creatine, Metafolin
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Diego