Clinical trials: Development Delay
Inguinal Hernia, Developmental Delay Disorders
Feasibility Study for PANDAS
We have been asked to participate in the Pediatric Anesthesia NeuroDevelopmental Assessment Study (PANDAS), which is a study to compare neurocognitive functions in sibling pairs: one of whom had exposure to anesthesia during…
- Trial name
- NCT00754897
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Children's Hospital of Philadelphia
Autism, Development Delay
Use of Virtual Reality Game Playing During Venipuncture
To evaluate the impact of using virtual reality, VR, game playing on successful completion and reduction of distress and pain in pediatric venipuncture, and to increase adherence in obtaining the desired blood volume.
- Conditions
- Autism, Development Delay, Typical Development
- Trial name
- NCT03518346
- Testing
- Virtual Reality, Standard of Care
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, Davis
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder
Mental And Speech Developmental Delay Autism Spectrum-Type Behavioral Disorder
FAMILY SYSTEM CITADEL 2060.METHODOLOGY "VOICE OF SLEEP MAMABEE 2026-2085 Systemic work with brain neurons through training modules at the border of sleep in clinical, psychological and strategic logic.
- Conditions
- Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder, Nervous System Disorder, Neurological Disorder
- Trial name
- NCT07670000
- Testing
- Audio fairy tales
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Natalia Poluektova
Development, Child, Adolescent Behavior
Developmental Intervention for Infants of Adolescent Mothers
This is a randomized control trial to evaluate a simple language intervention curriculum that utilizes LENA recordings, linguistic feedback and text-message review of content to improve language environments and outcomes for…
- Conditions
- Development, Child, Adolescent Behavior, Language Development, Language Delay
- Trial name
- NCT03547492
- Testing
- Teaching Talking, LENA recordings-language, LENA recordings-motor
- Volunteers
- 108 people
- Sponsor
- Women and Infants Hospital of Rhode Island
MNRI, Development Delay
Effects of MNRI Therapy on Fine Motor Skills in Children With Developmental Delays.
Developmental delay refers to a child's failure to achieve age-appropriate developmental milestones and may affect multiple developmental domains.
- Trial name
- NCT07764926
- Testing
- MNRI, Conventional Physiotherapy without MNRI
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Language Delay
pBFS Guided aiTBS Over Language Network for ASD Child
The aim of this trial is to evaluate the efficacy and safety of precision neuromodulation in improving language ability in children with autism spectrum disorder (ASD) who also have language development delay.
- Trial name
- NCT06950437
- Testing
- active iTBS, speech therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Changping Tianhe Research Institute of Brain Science
Developmental Delay
Early Intervention Therapy for Children With Delayed Development: Enabling Access in India's Rural Communities
This study is a cohort longitudinal design, also known as within subject repeated measures' design to measure the impact of an early identification and intervention program being implemented by Amar Seva Sangam (ASSA), an Indian…
- Trial name
- NCT03202966
- Testing
- Rehabilitation therapy
- Where
- 2 sites in India
- Volunteers
- 1,050 people
- Sponsor
- Amar Seva Sangam
Speech and Language Disorder, Speech Therapy
Providing Speech Therapy Awareness in Private Schools
There has been limited research in the area of speech and language therapy awareness in Pakistan. The study aims to assess the efficacy of providing speech therapy awareness in private schools through a pre-post model.
- Conditions
- Speech and Language Disorder, Speech Therapy, Speech Delay, Swallowing Disorder
- Trial name
- NCT04505696
- Testing
- Speech-Language Pathology Presentation
- Where
- Pakistan
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cerebral Palsy, Chewing Problem
Chewing Performance Level and Gross Motor Function in Children With Cerebral Palsy
The purpose of this study is to determine the association between gross motor function and chewing performance level in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy, Chewing Problem, Gross Motor Development Delay
- Trial name
- NCT02984735
- Testing
- Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Hacettepe University
Autism, Autistic Disorder
Early Characteristics of Autism
This study will identify factors that distinguish children with autism from children with developmental delay and those with normal development and study the efficacy of intensive behavioral therapy in children with autism.
- Trial name
- NCT00090415
- Testing
- Intensive behavioral therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Washington
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Cerebral Palsy Children, Children With Traumatic Brain Injury
Cerebrolysin Neural Repair Therapy in Children With Traumatic Brain Injury and Cerebral Palsy
Cerebral palsy (CP) is the most frequent cause of motor handicap among children. The economic burden of CP in USA includes $1.18 billion in direct medical costs, $1.05 billion in direct non-medical costs, and an additional $9.24…
- Conditions
- Cerebral Palsy Children, Children With Traumatic Brain Injury, Mental Handicap, Delayed Speech Development
- Trial name
- NCT02116348
- Testing
- Cerebrolysin (Nerve growth factor)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Gross Motor Development Delay
Video-based Assessment of Preschool Children's Gross Motor Development
Artificial intelligence (AI) is currently one of the global focal points for industrial development, with its applications in healthcare steadily increasing, such as in disease prediction, image diagnosis, and drug development.
- Trial name
- NCT07054437
- Testing
- Gross Motor Development Screening Tool
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Chang Gung Memorial Hospital
Mental Health Wellness 1, Parent-Child Relations
BRIGHT Coaching Program for Families
Children with, or at elevated risk for, brain-based developmental disabilities can experience lifelong consequences and challenges throughout their development.
- Conditions
- Mental Health Wellness 1, Parent-Child Relations, Child Developmental Delay, Parenting
- Trial name
- NCT03880383
- Testing
- Coaching, Online parent education, Online peer support
- Where
- 4 sites in Canada
- Volunteers
- 306 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cognitive Disorder, Metabolic Disease
Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency
Background: Creatine transporter deficiency (CTD) is a genetic disorder that mainly affects the brain in males. CTD causes intellectual disability that can be mild to severe.
- Conditions
- Cognitive Disorder, Metabolic Disease, Autism Spectrum Disorder
- Trial name
- NCT05600946
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Neuro Developmental Delay, Sensory Disorders
Aquatic Therapy Versus Sensory Room Intervention for Sensory-Motor Function in Children With Sensory Processing Disorder
This randomized clinical trial compares the effects of aquatic therapy and conventional sensory room intervention on adaptive neural responses and sensory-motor praxis in children with Monochannel Sensory Processing Disorder.
- Trial name
- AQUA vs SRI Tr (NCT07646951)
- Testing
- Aquatic Therapy
- Volunteers
- 60 people
- Sponsor
- MTI University
Movement Disorders in Children, Neuro Developmental Delay
Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD)
This observational patient registry aims to describe the clinical phenotypes and genetic findings of Vietnamese children with movement disorders of unknown etiology.
- Conditions
- Movement Disorders in Children, Neuro Developmental Delay, Neurogenetic Disorders
- Trial name
- VPeMD (NCT07695610)
- Testing
- Whole-Exome Sequencing
- Where
- 2 sites in Vietnam
- Volunteers
- 50 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Iron Deficiency, Neonatal Hyperbilirubinemia
Early Versus Delayed Cord Clamping at Term: Outcomes in Swedish Infants
Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth.
- Trial name
- NCT01245296
- Testing
- Timing of clamping the umbilical cord
- Where
- Sweden
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Uppsala University