Clinical trials: Development Delay
Craniosynostosis, Sagittal, Scaphocephaly
Examination of Neuromotor Development of Cases Diagnosed with Scaphocephaly
It's an observational study. Purpose of the study: To evaluate the neuromotor development of scaphocephaly cases. 21 infants diagnosed with scaphocephaly aged 2-17 months were included.
- Conditions
- Craniosynostosis, Sagittal, Scaphocephaly, Developmental Delay
- Trial name
- NCT06294626
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Acıbadem Atunizade Hospital
Cerebral Palsy, Premature Birth
Early Movements as a Predictor of Future Developmental Delay
Cerebral Palsy (CP) is a major developmental problem. Major risk groups of CP, are preterm infants and multiple pregnancies. Previous studies using the General Movements methodology demonstrated early identification of CP, as…
- Trial name
- NCT00418808
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Iron Deficiency, Anemia of Prematurity
Neurodevelopment After Early Iron Supplementation
Background: Iron deficiency in early childhood may impair neurodevelopment. Aim: To examine whether early iron supplementation improved neurodevelopment in preterm infants.
- Conditions
- Iron Deficiency, Anemia of Prematurity, Neurodevelopmental Delay
- Trial name
- NCT00457990
- Testing
- Oral administration of ferrous sulphate
- Where
- Germany
- Volunteers
- 204 people
- Sponsor
- University of Ulm
Epilepsy, Cerebral Palsy
A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging
This is a pilot study to determine if a standard bolus dose and infusion of dexmedetomidine can significantly decrease the dose of propofol (infusion) required for accomplishing an MRI.
- Conditions
- Epilepsy, Cerebral Palsy, Developmental Delay
- Trial name
- NCT02633241
- Testing
- Dexmedetomidine bolus and high infusion-Propofol, Dexmedetomidine bolus and low infusion-Propofol, Dexmedetomidine bolus only - Propofol
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Joseph Cravero
CTNNB1 Gene Mutation
Genotype-phenotype Correlations in Children and Adults With CTNNB1 Mutation
The aim of this study is to explore and define the correlations between genotype and phenotype in patients with CTNNB1 mutations as well as monitor and survey the natural history of the CTNNB1 syndrome.
- Trial name
- Gen-Phe CTNNB1 (NCT04812119)
- Testing
- The Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F), The Autism Spectrum Quotient-Children's Version (AQ-Child), The Autism-Spectrum Quotient (AQ)-Adolescent Version (AQ-Adolescent)
- Where
- 3 sites in Australia, Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Autism, Developmental Delay Disorders
Project EARLY: Engagement, Assessment, Referral, & Linkage for Young Children
Emerging evidence demonstrates that Autism Spectrum Disorder (ASD) can be reliably diagnosed by age two, and that early identification and intervention can improve outcomes.
- Trial name
- NCT02359084
- Testing
- Family Navigation, Conventional Care Management
- Where
- 10 sites in United States
- Volunteers
- 340 people
- Sponsor
- Boston University
Neuropsychiatric Disorder, Neurological Disorder
Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
Background: Many psychiatric, behavioral, and developmental disorders are genetic. This means that they tend to run in families. Some begin in childhood, while others do not appear until adulthood.
- Conditions
- Neuropsychiatric Disorder, Neurological Disorder, Neurodevelopmental Disorder, Sleep
- Trial name
- NCT01778504
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- National Institute of Mental Health (NIMH)
Maternal Depression
Reducing Risk After an Adverse Pregnancy Outcome
This application to the Boston University Medical Center Institutional Review Board outlines a research plan devoted to identifying and managing maternal depression in Early Intervention (EI).
- Trial name
- NCT01182363
- Testing
- Project Solve Education
- Where
- 4 sites in United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Fluoride Poisoning, Hemoglobin
Using Eggshell Calcium to Mitigate Fluorosis in Ethiopia
Mothers and young children in rural Ethiopia lack sufficient nutrition, and a compounding factor is presence of high levels of fluoride (> 5-10 mg/day) affecting body functions.
- Conditions
- Fluoride Poisoning, Hemoglobin, Underweight, Stunting
- Trial name
- NCT03355222
- Testing
- Promotion of chicken eggs
- Where
- Ethiopia
- Volunteers
- 270 people
- Sponsor
- University of Saskatchewan
Child Development, Child Development Disorder
The Indonesian Version of Ages and Stages Questionnaire III Accuracy Compared to Bayley Scales of Infant Development III
This study aimed to evaluate the concurrent validity information of the 24-, 30-, and 36-month Indonesian ASQ-3 with the Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) in Indonesian children.
- Conditions
- Child Development, Child Development Disorder, Development Delay, Developmental Delay
- Trial name
- NCT05408351
- Where
- Indonesia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
The Ability to Delay Gratification
Development, Attention, and Inhibition Study
The goal of this clinical trial is to test the associations of young children's early life experiences with delaying behaviors and links with later life outcomes.
- Trial name
- DAISY (NCT06605001)
- Testing
- Delay of Gratification
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Klinefelter Syndrome, Trisomy X
The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy
This study is designed to research the natural history of neurodevelopment, health and early hormonal function in infants with XXY/Klinefelter syndrome, XYY, XXX and other sex chromosome variations in an effort to identify early…
- Conditions
- Klinefelter Syndrome, Trisomy X, XYY Syndrome, XXXY and XXXXY Syndrome
- Trial name
- NCT03396562
- Testing
- Assessments of Development and Growth
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Delayed Visual Maturation
Delayed Visual Maturation: Outcome and Predictive Factors
The objectives of the study are to describe the developmental outcome in a population of children with delayed visual maturation.
- Trial name
- DVM (NCT04251338)
- Where
- Belgium
- Volunteers
- 71 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Language Delay, Language Development Disorders
Vocabulary Intervention for Late Talkers
Most studies regarding word learning have focused on understanding when and how infants learn words. At 24 months, typically developing infants know between 200 and 300 words and add new words to their vocabularies at a rapid…
- Trial name
- NCT03379818
- Testing
- Shape training intervention, Specific word training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham
Obesity, Blood Pressure
Upstate New York Infant Development Screening Program
The goal of the Upstate KIDS Study is to track the growth, development and long-term health of children given the increasing use of infertility treatment, occurrence of maternal obesity and pregnancy complications, and rising…
- Conditions
- Obesity, Blood Pressure, Motor Delay, Developmental Delay
- Trial name
- Upstate KIDS (NCT03106493)
- Testing
- None (observational)
- Volunteers
- 6,171 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Vitamin B 12 Deficiency
Cobalamin Status in Young Children With Developmental Delay
During fetal life and infancy, an adequate cobalamin status is important for normal growth and central nervous system development.
- Trial name
- NCT00710138
- Testing
- Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Infants With or at Risk/Concern for Developmental Delay
Otteroo Case Series
Rationale. The Otteroo is a floatie which supports an infant or young child with their head above and their body in water. Researchers are proposing that the Otteroo may be a good "tool" to facilitate exploring the ability to…
- Trial name
- NCT03502265
- Testing
- Otteroo
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Southern California
Child Language, Language Delay
Talk With Me Baby: Leveraging Well-Child Care to Enhance the Early Home Language Environment
Language-rich interactions with a parent or caregiver can serve as a protective factor for young children, by supporting their language development and other positive long-term outcomes, but existing interventions have not had…
- Conditions
- Child Language, Language Delay, Developmental Milestones
- Trial name
- TWMB (NCT07132411)
- Testing
- Patients in Talk With Me Baby Clinics, Patients in Care-As-Usual Clinics
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Kansas Medical Center
Younger Sibling of Child With Autism Spectrum Disorder, Signs of Developmental Delay
Effects of a Short-term Parent Mediated Social Training on Developmental Trajectories in Infants
This study is being done to examine the feasibility and impact of the Infant Achievements caregiver coaching treatment on caregiver child-engagement strategies used during play with their infant.
- Conditions
- Younger Sibling of Child With Autism Spectrum Disorder, Signs of Developmental Delay, Signs of Communication Delay, Signs of Social Delay
- Trial name
- IA (NCT03404505)
- Testing
- Infant Achievements, Caregiver Education (CE)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.