Clinical trials: Development Disorders
Marfan Syndrome
Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome
The purpose of this study is to evaluate if losartan limits aortic dilatation in patients with Marfan syndrome.
- Trial name
- MARFANSARTAN (NCT00763893)
- Testing
- Losartan
- Where
- France
- Volunteers
- 303 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
OPT-IN: Online Parent Training Intervention for Young Children Diagnosed With Autism Spectrum Disorder
The goal of this observer-blinded randomized controlled clinical trial is to determine the effectiveness of a fully-online, parent-mediated, video-based, self-directed intervention for young children with autism (12-60 months)…
- Trial name
- NCT06011707
- Testing
- OPT-IN, Psychoeducational control
- Volunteers
- 308 people
- Sponsor
- Elizabeth Kelley
Autism Spectrum Disorder
A Virtual Dental Office Experience for Children With Autism Spectrum Disorder
The objective of this study is to evaluate the effectiveness of virtual reality (360° video) compared to a social story for reducing pre-visit dental anxiety for children with autism spectrum disorder (ASD) improve the dental…
- Trial name
- NCT05196230
- Testing
- Control Condition (Social Story), Experimental Condition (360° Video)
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Effectiveness of a Parent-mediated Intervention With PACT on Children With ASD
Autism Spectrum Disorder (ASD) is a neuro-developmental disorders. There are different types of interventions. Among these interventions Early Start Denver Model (ESDM) and Preschool Autism Communication Therapy (PACT) have…
- Trial name
- IFPAD (NCT04244721)
- Testing
- Preschool Autism Communication Therapy (PACT), Treatment As Usual (TAU)
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Hôpital le Vinatier
Pediatric Growth Hormone Deficiency
Versartis Long-Term Safety Study of Somavaratan
Protocol 13VR3 is is a multi-center, open-label study assessing long-term somavaratan administration. Patients will be monitored for safety throughout their participation in the study.
- Trial name
- VISTA (NCT02068521)
- Testing
- somavaratan
- Volunteers
- 385 people
- Sponsor
- Versartis Inc.
Infertility and at High Risk of OHSS
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022241
- Testing
- triptorelin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chenshiling
Autism Spectrum Disorder
Treatment by Therapeutic Body Wraps in Children and Adolescents Suffering From Autism With Severe Injurious Behavior.
Severe injurious behaviors in children with autism spectrum disorder are challenging. First line treatment approaches include behavioral techniques but pharmacotherapy is frequently required despite frequent adverse effects in…
- Trial name
- PACKING (NCT03164746)
- Testing
- Dry sheet Therapeutic body wraps, WET sheet Therapeutic body wraps
- Where
- 13 sites in France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Lille
Klinefelter Syndrome, XXY Syndrome
Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome
The purpose of this study is to determine if testosterone replacement therapy leads to changes in psychological factors and/or motor skills in adolescent males with 47,XXY (also called Klinefelter syndrome).
- Trial name
- TestoXXY/KS (NCT01585831)
- Testing
- Testosterone gel 1%
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Colorado, Denver
Attention Deficit Disorder With Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
External Trigeminal Nerve Stimulation for Children With ASD + ADHD to Reduce Elevated Symptoms
The goal of this clinical trial is to learn if external trigeminal nerve stimulation (eTNS) works to treat ADHD symptoms in children on the autism spectrum (ASD).
- Trial name
- eTNS CARES (NCT07214545)
- Testing
- Trigeminal Nerve Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Osteogenesis Imperfecta
Post-market Observational Study on JTIN Telescopic Nail in Osteogenesis Imperfecta Pediatric Patients
This study has been planned as part of the Orthofix Srl post-market active surveillance plan for the collection of data on both the clinical performance and the safety profile of the JTIN.
- Trial name
- JTIN (NCT05612139)
- Testing
- JTIN implantation surgery
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Orthofix s.r.l.
Autism Spectrum Disorder, Speech
Thinking in Speech for Children With Autism
This study examines a cognitive therapy for autistic children, Thinking in Speech. Thinking in Speech helps children with autism independently cope with everyday events that cause stress, by developing their ability to use "inner…
- Trial name
- NCT05256095
- Testing
- Thinking in Speech
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
Preterm Infant
Development, ADL, Participation, and Quality of Life in Preterm Infants: Longitudinal Research
The three fundamental goals of early rehabilitation for preterm infant after leaving NICU are: optimizing function within each child's prognostic potential, preventing the development of secondary conditions that impact life-long…
- Trial name
- NCT06532695
- Testing
- No intervention will be provided.
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Visual Developmental Disorders
Tertiary Care for Visual Developmental Disorders in Pre-school Children
Visual development disorders are major public health problems among children especially in China. How to find an effective and economic way to manage the larger number of children in China remains exploring.
- Trial name
- NCT03251456
- Testing
- Tertiary care, Usual Care
- Where
- China
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Tuberous Sclerosis Complex
Studies in Patients With Tuberous Sclerosis Complex
This study is aimed to carry out a systematic study to examine the effects of genetic variants (genetic modifiers) other than TSC genes on phenotypic variability in familial TSC patients (affected parent, child and unaffected…
- Trial name
- NCT03276195
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Translational Genomics Research Institute
Very Low Birth Weight Baby, Premature Birth
Human-derived Human Milk Fortifiers (H2MF), Gut Microbiota and Oxidative Stress in Premature Infants
This is a randomized controlled trial of a human-derived human milk fortifier (H2MF) vs standard bovine-derived human milk fortifier (HMF) evaluating fecal microbiota and fecal and urinary biomarkers of oxidative stress in…
- Conditions
- Very Low Birth Weight Baby, Premature Birth, Microbial Colonization, Oxidative Stress
- Trial name
- NCT03214822
- Testing
- H2MF
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Osteogenesis Imperfecta
Dental Malocclusion and Craniofacial Development in OI
Osteogenesis imperfecta (OI) is a rare inherited disorder that causes bones to break easily. Individuals with osteogenesis imperfecta break bones often and may have other problems, including hearing loss and pain and difficulty…
- Trial name
- NCT02934451
- Where
- 3 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder
The Effect of Individualised Homoeopathic Treatment of Autism Spectrum Disorder in Children
The aim of this study is to determine the effect of individualised homoeopathic treatment of children with Autism Spectrum Disorder (ASD).This study is of descriptive case study design, with a structured interview and…
- Trial name
- NCT02363673
- Testing
- Individualised homoeopathic remedy in aqua distilla
- Where
- South Africa
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Virtual Buddy Movement Therapy for Psychomotor and Social Development in Pediatric Oncology Patients in Remission
Acute lymphoblastic leukemia is the most common type of cancer in children diagnosed between the ages of two and five. After cancer treatment, children suffer from fatigue and exhaustion, and thus a decrease in daily physical…
- Trial name
- NCT07522905
- Testing
- Virtual BUDDY-Movement Therapy
- Where
- Slovakia
- Volunteers
- 24 people
- Sponsor
- Comenius University
Autism, Asperger Syndrome
The Development of Autistic Children Based on Mothers´Response in Autism Behavior Checklist
The purpose of this study is to evaluate the process of development of autistic children, in a direct and indirect intervention context from mother´s response in Autism Behavior Checklist.
- Trial name
- NCT00725556
- Testing
- Speech Therapy
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Federal University of São Paulo
Autism Spectrum Disorder (ASD)
Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children Aged From 2 to Less Than 7 Years Old With Autism Spectrum Disorder.
The purpose of this study was to evaluate the efficacity and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.
- Trial name
- NCT03715153
- Testing
- BUMETANIDE (S95008) for week 0 - 26, Open-Label BUMETANIDE (S95008) for weeks 26 - 52
- Where
- 50 sites in United States, Australia and 10 more
- Volunteers
- 211 people
- Sponsor
- Institut de Recherches Internationales Servier
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